Human CD117/c-kit Antibody | R&D Systems MAB332-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD117/c-kit Antibody

catalog :

MAB332-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

47233

reactivity :

human

application :

western blot, ELISA, neutralization, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Rønnov Jessen L, Kim J, Goldhammer N, Klitgaard M, Smicius M, Bechmann M, et al. Desensitization of human breast progenitors by a transient exposure to pregnancy levels of estrogen. Sci Rep. 2021;11:17232 pubmed publisher
Wu W, Wang C, Chen H, Zhou J, Zhang J, Gao L, et al. House dust mite allergens mediate the activation of câ€‘kit in dendritic cells via Tollâ€‘like receptor 2. Mol Med Rep. 2015;12:5307-13 pubmed publisher
Miyahara K, Nouso K, Morimoto Y, Takeuchi Y, Hagihara H, Kuwaki K, et al. Pro-angiogenic cytokines for prediction of outcomes in patients with advanced hepatocellular carcinoma. Br J Cancer. 2013;109:2072-8 pubmed publisher
Pan J, Quintas Cardama A, Kantarjian H, Akin C, Manshouri T, Lamb P, et al. EXEL-0862, a novel tyrosine kinase inhibitor, induces apoptosis in vitro and ex vivo in human mast cells expressing the KIT D816V mutation. Blood. 2007;109:315-22 pubmed
Ameredes B, Calhoun W. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle. J Allergy Clin Immunol. 2005;116:65-72 pubmed

product information

master code :

MAB332

SKU :

MAB332-100

product name :

Human CD117/c-kit Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CD117/c-kit Antibody from R&D Systems is a mouse monoclonal antibody to CD117/c-kit. This antibody reacts with human. The Human CD117/c-kit Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,Simple Western,Neutralization,ELISA Capture (Matched Antibody Pair),CyTOF-ready.

target :

CD117/c-kit

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

47233

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CD117/c-kit, Gln26-Thr520, Accession # P10721

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CD117/c-kit in ELISAs and Western blots. In sandwich immunoassays and Western blots, no cross-reactivity with recombinant mouse CD117 is observed.

gene symbol :

KIT

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by SCF/c-kit Ligand and Neutralization by Human CD117/c-kit Antibody.

accessionNumbers :

P10721

applications :

Flow Cytometry,Immunoprecipitation,Western Blot,Simple Western,Neutralization,ELISA Capture (Matched Antibody Pair),CyTOF-ready

USD :

489 USD

alt names :

CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, KIT, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCF R, SCFR, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage