Human M-CSF R/CD115 Antibody | R&D Systems MAB3291-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human M-CSF R/CD115 Antibody

catalog :

MAB3291-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

61701

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; 1:500; loading ...	Emre C, Do K, Jun B, Hjorth E, Alcalde S, Kautzmann M, et al. Age-related changes in brain phospholipids and bioactive lipids in the APP knock-in mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2021;9:116 pubmed publisher
	Dorion M, Casas D, Shlaifer I, Yaqubi M, Fleming P, Karpilovsky N, et al. An adapted protocol to derive microglia from stem cells and its application in the study of CSF1R-related disorders. Mol Neurodegener. 2024;19:31 pubmed publisher
	Tkach M, Thalmensi J, Timperi E, Guéguen P, Nevo N, Grisard E, et al. Extracellular vesicles from triple negative breast cancer promote pro-inflammatory macrophages associated with better clinical outcome. Proc Natl Acad Sci U S A. 2022;119:e2107394119 pubmed publisher
	Gao X, Jia G, Guttman A, DePianto D, Morshead K, Sun K, et al. Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis. Cell Rep Med. 2020;1:100140 pubmed publisher
	Woo H, Lee S, Stoffer J, Rush D, Chambers S. Phenotype of vigilin expressing breast cancer cells binding to the 69 nt 3'UTR element in CSF-1R mRNA. Transl Oncol. 2019;12:106-115 pubmed publisher
	Wang B, Ma Z, Wang M, Sun X, Tang Y, Li M, et al. IL-34 Upregulated Th17 Production through Increased IL-6 Expression by Rheumatoid Fibroblast-Like Synoviocytes. Mediators Inflamm. 2017;2017:1567120 pubmed publisher
	Zwicker S, Bureik D, Bosma M, Martinez G, Almer S, Boström E. Receptor-Type Protein-Tyrosine Phosphatase ? and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1. PLoS ONE. 2016;11:e0167324 pubmed publisher
	Pignatelli J, Goswami S, Jones J, Rohan T, Pieri E, Chen X, et al. Invasive breast carcinoma cells from patients exhibit MenaINV- and macrophage-dependent transendothelial migration. Sci Signal. 2014;7:ra112 pubmed publisher
	Patsialou A, Wang Y, Pignatelli J, Chen X, Entenberg D, Oktay M, et al. Autocrine CSF1R signaling mediates switching between invasion and proliferation downstream of TGF? in claudin-low breast tumor cells. Oncogene. 2015;34:2721-31 pubmed publisher
	Forgèt M, Voorhees J, Cole S, Dakhlallah D, Patterson I, Gross A, et al. Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer. PLoS ONE. 2014;9:e98623 pubmed publisher
	Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, et al. Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma. Nat Med. 2010;16:571-9, 1p following 579 pubmed publisher

product information

master code :

MAB3291

SKU :

MAB3291-100

product name :

Human M-CSF R/CD115 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human M-CSF R/CD115 Antibody from R&D Systems is a mouse monoclonal antibody to M-CSFR/CD115. This antibody reacts with human,mouse. The Human M-CSF R/CD115 Antibody has been validated for the following applications: Neutralization,Western Blot,Bioassay,Immunoprecipitation,Functional Assay,Immunocytochemistry,Immunohistochemistry.

target :

M-CSF R/CD115

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

61701

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human M-CSF R/CD115, Ile20-Glu512 (Pro54Ala), Accession # P07333.2

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human M-CSF R/CD115 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) GM-CSF R alpha or rhGM-CSF R▀ is observed.

gene symbol :

CSF1R

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Human M-CSF R/CD115 antibody by Western Blot.

accessionNumbers :

P07333.2

applications :

Western Blot,Bioassay,Immunoprecipitation,Neutralization,Functional Assay,Immunocytochemistry,Immunohistochemistry

USD :

489 USD

alt names :

CD115, CD115 antigen, C-FMS, colony stimulating factor 1 receptor, CSF1R, CSF-1-R, CSFR, EC 2.7.10.1, FMS proto-oncogene, FMSFIM2, macrophage colony stimulating factor I receptor, macrophage colony-stimulating factor 1 receptor, McDonough feline sarcoma viral (v-fms) oncogene homolog, MCSFR, M-CSFR, Proto-oncogene c-Fms

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage