product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Mouse/Rat TRAF-2 Antibody
catalog :
MAB3277
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
324522
reactivity :
human, mouse, rat
application :
western blot, immunocytochemistry
more info or order :
citations: 6
Published Application/Species/Sample/DilutionReference
  • western blot; human
Jin H, Jin X, Lee J. Zinc-finger protein 91 plays a key role in LIGHT-induced activation of non-canonical NF-?B pathway. Biochem Biophys Res Commun. 2010;400:581-6 pubmed publisher
  • western blot; human
Kolliputi N, Waxman A. IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am J Respir Cell Mol Biol. 2009;40:314-24 pubmed publisher
  • western blot; mouse
Pobezinskaya Y, Kim Y, Choksi S, Morgan M, Li T, Liu C, et al. The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors. Nat Immunol. 2008;9:1047-54 pubmed publisher
De Luca A, Faienza F, Fulci C, Nicolai E, Calligari P, Palumbo C, et al. Molecular and cellular evidence of a direct interaction between the TRAF2 C-terminal domain and ganglioside GM1. Int J Biochem Cell Biol. 2024;167:106508 pubmed publisher
Frankish J, Mukherjee D, Romano E, Billian Frey K, Schr xf6 der M, Heinonen K, et al. The CD40 agonist HERA-CD40L results in enhanced activation of antigen presenting cells, promoting an anti-tumor effect alone and in combination with radiotherapy. Front Immunol. 2023;14:1160116 pubmed publisher
Fang D, He K, Wang N, Sang Z, Qiu X, Xu G, et al. NEDD4 ubiquitinates TRAF3 to promote CD40-mediated AKT activation. Nat Commun. 2014;5:4513 pubmed publisher
product information
master code :
MAB3277
SKU :
MAB3277
product name :
Human/Mouse/Rat TRAF-2 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Mouse/Rat TRAF-2 Antibody from R&D Systems is a mouse monoclonal antibody to TRAF-2. This antibody reacts with human,mouse,rat. The Human/Mouse/Rat TRAF-2 Antibody has been validated for the following applications: Western Blot,Functional Assay,Immunocytochemistry,Knockout Validated.
target :
TRAF-2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
324522
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human TRAF-2, Met1-Leu501, Accession # Q12933
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human, mouse, and rat TRAF-2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human TRAF-1, -3, -4, -5, or -6 is observed.
gene symbol :
TRAF2
Antibody validation :
Knockout/Knockdown
top caption :
Detection of Human/Mouse/Rat TRAF-2 antibody by Western Blot.
accessionNumbers :
Q12933
applications :
Western Blot,Functional Assay,Immunocytochemistry,Knockout Validated
USD :
439 USD
alt names :
E3 ubiquitin-protein ligase TRAF2, EC 6.3.2.-, MGC:45012, TNF receptor-associated factor 2, TRAF2, TRAP3, TRAP3TRAP, tumor necrosis factor type 2 receptor associated protein 3, Tumor necrosis factor type 2 receptor-associated protein 3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.