Human CTLA-4 Antibody | R&D Systems MAB325-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CTLA-4 Antibody

catalog :

MAB325-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

48815

reactivity :

human

application :

western blot, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 3

Reference
Motavalli R, Hosseini M, Soltani Zangbar M, Karimi A, Sadeghi M, Dolati S, et al. Evaluation of the immune checkpoint factors in idiopathic membranous nephropathy. Mol Cell Probes. 2023;69:101914 pubmed publisher
Argüello R, Albareda M, Alvarez M, Bertocchi G, Armenti A, Vigliano C, et al. Inhibitory receptors are expressed by Trypanosoma cruzi-specific effector T cells and in hearts of subjects with chronic Chagas disease. PLoS ONE. 2012;7:e35966 pubmed publisher
Srinivasan M, Eri R, Zunt S, Summerlin D, Brand D, Blum J. Suppression of immune responses in collagen-induced arthritis by a rationally designed CD80-binding peptide agent. Arthritis Rheum. 2007;56:498-508 pubmed

product information

master code :

MAB325

SKU :

MAB325-100

product name :

Human CTLA-4 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CTLA-4 Antibody from R&D Systems is a mouse monoclonal antibody to CTLA-4. This antibody reacts with human. The Human CTLA-4 Antibody has been validated for the following applications: Binding Assay,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin.

target :

CTLA-4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

48815

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human CTLA-4, Ala37-Phe162 (Thr174Ala), Accession # Q6GR94

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CTLA-4 in direct ELISAs and Western blots. Shows approximately 10% cross-reactivity with recombinant mouse CTLA-4 and no cross-reactivity with recombinant human (rh) CD28 or rhICOS.

gene symbol :

CTLA4

accessionNumbers :

Q6GR94

applications :

Binding Assay,Western Blot,Neutralization,Functional Assay,Immunohistochemistry-Paraffin

USD :

459 USD

alt names :

CD, CD152, CD152 antigen, CD152IDDM12, CD28, celiac disease 3, CELIAC3, CTLA4, CTLA-4, cytotoxic T-lymphocyte antigen 4, cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4, cytotoxic T-lymphocyte-associated protein 4, cytotoxic T-lymphocyte-associated serine esterase-4, GRD4, GSE, ICOS, ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage