Human/Mouse FGF-8 Antibody | R&D Systems MAB323-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse FGF-8 Antibody

catalog :

MAB323-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

47109

reactivity :

human, mouse, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 9

Reference
Nowialis P, Lopušná K, Opavska J, Haney S, Abraham A, Sheng P, et al. Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nat Commun. 2019;10:4374 pubmed publisher
Bae J, Clarke J, Rashid H, ADHAMI M, McCullough K, Scott J, et al. Specificity Protein 7 Is Required for Proliferation and Differentiation of Ameloblasts and Odontoblasts. J Bone Miner Res. 2018;33:1126-1140 pubmed publisher
Chan W, Price D, Pratt T. FGF8 morphogen gradients are differentially regulated by heparan sulphotransferases Hs2st and Hs6st1 in the developing brain. Biol Open. 2017;6:1933-1942 pubmed publisher
Bluemn E, Coleman I, Lucas J, Coleman R, Hernández López S, Tharakan R, et al. Androgen Receptor Pathway-Independent Prostate Cancer Is Sustained through FGF Signaling. Cancer Cell. 2017;32:474-489.e6 pubmed publisher
Fresco V, Kern C, Mohammadi M, Twal W. Fibulin-1 Binds to Fibroblast Growth Factor 8 with High Affinity: EFFECTS ON EMBRYO SURVIVAL. J Biol Chem. 2016;291:18730-9 pubmed publisher
Yang S, Yang M, Herrlinger S, Liang C, Lai F, Chen J. MiR-302/367 regulate neural progenitor proliferation, differentiation timing, and survival in neurulation. Dev Biol. 2015;408:140-50 pubmed publisher
Nonomura K, Yamaguchi Y, Hamachi M, Koike M, Uchiyama Y, Nakazato K, et al. Local apoptosis modulates early mammalian brain development through the elimination of morphogen-producing cells. Dev Cell. 2013;27:621-34 pubmed publisher
Wang C, Xia C, Bian W, Liu L, Lin W, Chen Y, et al. Cell aggregation-induced FGF8 elevation is essential for P19 cell neural differentiation. Mol Biol Cell. 2006;17:3075-84 pubmed
Alsan B, Schultheiss T. Regulation of avian cardiogenesis by Fgf8 signaling. Development. 2002;129:1935-43 pubmed

product information

master code :

MAB323

SKU :

MAB323-100

product name :

Human/Mouse FGF-8 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human/Mouse FGF-8 Antibody from R&D Systems is a mouse monoclonal antibody to FGF-8. This antibody reacts with avian - chicken,human,mouse. The Human/Mouse FGF-8 Antibody has been validated for the following applications: Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,In ovo assay,Immunocytochemistry,Neutralization.

target :

FGF-8

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

47109

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant mouse FGF-8b, Gln23-Arg215, Accession # NP_001159834

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Avian - Chicken,Human,Mouse

specificity :

Detects human and mouse FGF-8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human (rh) FGF-5, rhFGF-7, and rhFGF-9 is observed.

gene symbol :

FGF8

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by FGF-8 and Neutralization by Human and Mouse FGF-8 Antibody.

accessionNumbers :

NP_001159834

applications :

Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,In ovo assay,Immunocytochemistry,Neutralization

USD :

469 USD

alt names :

AIGF, AIGFKAL6, Androgen-induced growth factor, FGF8, FGF-8, fibroblast growth factor 8, fibroblast growth factor 8 (androgen-induced), HBGF-8, Heparin-binding growth factor 8, MGC149376

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage