Human VEGFR1/Flt-1 Antibody | R&D Systems MAB321 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGFR1/Flt-1 Antibody

catalog :

MAB321

quantity :

100 ug (also 25 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

49560

reactivity :

human

application :

western blot, flow cytometry

citations: 10

Reference
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed publisher
Jarajapu Y, Hazra S, Segal M, Li Calzi S, LiCalzi S, Jadhao C, et al. Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms. PLoS ONE. 2014;9:e93965 pubmed publisher
Facciabene A, Peng X, Hagemann I, Balint K, Barchetti A, Wang L, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature. 2011;475:226-30 pubmed publisher
Brave S, Eberlein C, Shibuya M, Wedge S, Barry S. Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model. Angiogenesis. 2010;13:337-47 pubmed publisher
Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J. Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells. Cancer Res. 2009;69:1976-84 pubmed publisher
Riccioni R, Senese M, Diverio D, Riti V, Mariani G, Boe A, et al. Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels. Leuk Res. 2008;32:1244-58 pubmed publisher
Lin Y, Liang Y, Chiang B. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J Leukoc Biol. 2007;82:1473-80 pubmed
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, et al. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells. 2007;25:1862-71 pubmed
Caldas H, Fangusaro J, Boue D, Holloway M, Altura R. Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis. Blood. 2007;109:1479-89 pubmed
Caine G, Blann A, Stonelake P, Ryan P, Lip G. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1. Eur J Clin Invest. 2003;33:883-90 pubmed

product information

brand :

R&D Systems

master code :

MAB321

SKU :

MAB321-100

product name :

Human VEGFR1/Flt-1 Antibody

description :

The Human VEGFR1/Flt-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR1/Flt-1. This antibody reacts with human. The Human VEGFR1/Flt-1 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, CyTOF-ready.

target :

VEGFR1/Flt-1

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

49560

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR1/Flt-1, Ser27-His687, Accession # NP_001153392

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human VEGFR1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGFR1, recombinant human (rh) VEGFR2, rhVEGFR3, or rhVEGFR4.

gene symbol :

FLT1

details of functionality :

ActivityAssaywCitation not found None None

catalog number base :

MAB321

accessionNumbers :

NP_001153392

applications :

Western Blot, Flow Cytometry, CyTOF-ready

2020 USD :

349

2021 USD :

369 USD

alt names :

EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.