Human VEGFR1/Flt-1 Antibody | R&D Systems MAB321-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human VEGFR1/Flt-1 Antibody

catalog :

MAB321-100

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

49560

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 14

Reference
Schulz A, Drost C, Hesse B, Beul K, Brand M, Di Marco G. The Soluble Fms-like Tyrosine Kinase-1 Contributes to Structural and Functional Changes in Endothelial Cells in Chronic Kidney Disease. Int J Mol Sci. 2022;23: pubmed publisher
Wei S, Huang Y, Hsieh M, Lin Y, Shyu W, Chen H, et al. Atypical chemokine receptor ACKR3/CXCR7 controls postnatal vasculogenesis and arterial specification by mesenchymal stem cells via Notch signaling. Cell Death Dis. 2020;11:307 pubmed publisher
Odent Grigorescu G, Rosca A, Preda M, Tutuianu R, Simionescu M, Burlacu A. Synergic effects of VEGF-A and SDF-1 on the angiogenic properties of endothelial progenitor cells. J Tissue Eng Regen Med. 2017;11:3241-3252 pubmed publisher
Palmer K, Kaitu u Lino T, Hastie R, Hannan N, Ye L, Binder N, et al. Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity. Hypertension. 2015;66:1251-9 pubmed publisher
Jarajapu Y, Hazra S, Segal M, Li Calzi S, LiCalzi S, Jadhao C, et al. Vasoreparative dysfunction of CD34+ cells in diabetic individuals involves hypoxic desensitization and impaired autocrine/paracrine mechanisms. PLoS ONE. 2014;9:e93965 pubmed publisher
Facciabene A, Peng X, Hagemann I, Balint K, Barchetti A, Wang L, et al. Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and T(reg) cells. Nature. 2011;475:226-30 pubmed publisher
Brave S, Eberlein C, Shibuya M, Wedge S, Barry S. Placental growth factor neutralising antibodies give limited anti-angiogenic effects in an in vitro organotypic angiogenesis model. Angiogenesis. 2010;13:337-47 pubmed publisher
Xu L, Hausmann M, Dietmaier W, Kellermeier S, Pesch T, Stieber Gunckel M, et al. Expression of growth factor receptors and targeting of EGFR in cholangiocarcinoma cell lines. BMC Cancer. 2010;10:302 pubmed publisher
Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J. Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells. Cancer Res. 2009;69:1976-84 pubmed publisher
Riccioni R, Senese M, Diverio D, Riti V, Mariani G, Boe A, et al. Resistance of acute myeloid leukemic cells to the triterpenoid CDDO-Imidazolide is associated with low caspase-8 and FADD levels. Leuk Res. 2008;32:1244-58 pubmed publisher
Lin Y, Liang Y, Chiang B. Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells. J Leukoc Biol. 2007;82:1473-80 pubmed
Riccioni R, Diverio D, Mariani G, Buffolino S, Riti V, Saulle E, et al. Expression of Tie-2 and other receptors for endothelial growth factors in acute myeloid leukemias is associated with monocytic features of leukemic blasts. Stem Cells. 2007;25:1862-71 pubmed
Caldas H, Fangusaro J, Boue D, Holloway M, Altura R. Dissecting the role of endothelial SURVIVIN DeltaEx3 in angiogenesis. Blood. 2007;109:1479-89 pubmed
Caine G, Blann A, Stonelake P, Ryan P, Lip G. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1. Eur J Clin Invest. 2003;33:883-90 pubmed

product information

master code :

MAB321

SKU :

MAB321-100

product name :

Human VEGFR1/Flt-1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human VEGFR1/Flt-1 Antibody from R&D Systems is a mouse monoclonal antibody to VEGFR1/Flt-1. This antibody reacts with human. The Human VEGFR1/Flt-1 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Flow Cytometry,Western Blot,Neutralization,Cell Culture,CyTOF-ready.

target :

VEGFR1/Flt-1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

49560

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human VEGFR1/Flt-1, Ser27-His687, Accession # NP_001153392

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human VEGFR1/Flt-1 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse VEGFR1, recombinant human (rh) VEGFR2, rhVEGFR3, or rhVEGFR4.

gene symbol :

FLT1

top caption :

Detection of VEGFR1/Flt-1 antibody in HUVEC Human Cells antibody by Flow Cytometry.

accessionNumbers :

NP_001153392

applications :

Immunohistochemistry,ELISA Development,Flow Cytometry,Western Blot,Neutralization,Cell Culture,CyTOF-ready

USD :

489 USD

alt names :

EC 2.7.10, EC 2.7.10.1, FLT, FLT1, FLT-1, Fms-like tyrosine kinase 1, fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascularpermeability factor receptor), FRT, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, vascular endothelial growth factor receptor 1, Vascular permeability factor receptor, VEGF R1, VEGFR1, VEGFR-1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage