Human/Mouse/Primate BMP-9 Antibody | R&D Systems MAB3209 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Primate BMP-9 Antibody

catalog :

MAB3209

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

360107

reactivity :

human, mouse

application :

western blot, ELISA, neutralization, blocking or activating experiments

citations: 12

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; mouse; fig 5c	Ruiz S, Chandakkar P, Zhao H, Papoin J, Chatterjee P, Christen E, et al. Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology. Hum Mol Genet. 2017;26:4786-4798 pubmed publisher
ELISA; mouse; loading ...; fig 1b	Ruiz S, Zhao H, Chandakkar P, Chatterjee P, Papoin J, Blanc L, et al. A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10. Sci Rep. 2016;5:37366 pubmed publisher
	Owen N, Alexander G, Sen S, Bunclark K, Polwarth G, Pepke Zaba J, et al. Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. EBioMedicine. 2020;56:102794 pubmed publisher
	Desroches Castan A, Tillet E, Ricard N, Ouarné M, Mallet C, Feige J, et al. Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice. Cells. 2019;8: pubmed publisher
	Graf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, et al. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nat Commun. 2018;9:1416 pubmed publisher
	Breitkopf Heinlein K, Meyer C, KÃ¶nig C, Gaitantzi H, Addante A, Thomas M, et al. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut. 2017;66:939-954 pubmed publisher
	Kienast Y, Jucknischke U, Scheiblich S, Thier M, de Wouters M, Haas A, et al. Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains. J Biol Chem. 2016;291:3395-410 pubmed publisher
	Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher
	Ricard N, Ciais D, Levet S, Subileau M, Mallet C, Zimmers T, et al. BMP9 and BMP10 are critical for postnatal retinal vascular remodeling. Blood. 2012;119:6162-71 pubmed publisher
	van Meeteren L, Thorikay M, Bergqvist S, Pardali E, Stampino C, Hu Lowe D, et al. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting. J Biol Chem. 2012;287:18551-61 pubmed publisher
	Yao Y, Jumabay M, Ly A, Radparvar M, Wang A, Abdmaulen R, et al. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood. 2012;119:5037-47 pubmed publisher
	Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB3209

SKU :

MAB3209-100

product name :

Human/Mouse/Primate BMP-9 Antibody

description :

The Human/Mouse/Primate BMP-9 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-9. This antibody reacts with human, mouse, primate. The Human/Mouse/Primate BMP-9 Antibody has been validated for the following applications: Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair).

target :

BMP-9

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

360107

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human BMP-9, Ser320-Arg429, Accession # Q9UK05

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse, Primate

specificity :

Detects human and primate BMP-9 in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human BMP-1, -1.1, -2, -3, -3b, -4, -5, -6, -7, -8, or -10 is observed. In direct ELISAs, approximately 80% cross-reactivity with recombinant mouse (rm) BMP-9 and 10% cross-reactivity with rmBMP-10 is observed.

gene symbol :

GDF2

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB3209

accessionNumbers :

Q9UK05

applications :

Western Blot, Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

BMP9, BMP9BMP-9Bone morphogenetic protein 9, GDF2, GDF-2, growth differentiation factor 2, growth/differentiation factor 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.