Human/Mouse/Primate BMP-9 Antibody | R&D Systems MAB3209-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse/Primate BMP-9 Antibody

catalog :

MAB3209-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

360107

reactivity :

human, mouse

application :

western blot, ELISA, neutralization, immunoprecipitation

more info or order :

R&D Systems product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig s7d	Ozawa T, Morikawa M, Morishita Y, Ogikubo K, Itoh F, Koinuma D, et al. Systemic administration of monovalent follistatin-like 3-Fc-fusion protein increases muscle mass in mice. iScience. 2021;24:102488 pubmed publisher
	Zhao C, Inada Y, Motoike S, Kamiya D, Hino K, Ikeya M. BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling. EMBO Mol Med. 2025;17:112-128 pubmed publisher
	Dinakaran S, Zhao H, Tang Y, Wang Z, Ruiz S, Nomura Kitabayashi A, et al. CDK6-mediated endothelial cell cycle acceleration drives arteriovenous malformations in hereditary hemorrhagic telangiectasia. bioRxiv. 2023;: pubmed publisher
	Owen N, Alexander G, Sen S, Bunclark K, Polwarth G, Pepke Zaba J, et al. Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. EBioMedicine. 2020;56:102794 pubmed publisher
	Desroches Castan A, Tillet E, Ricard N, Ouarné M, Mallet C, Feige J, et al. Differential Consequences of Bmp9 Deletion on Sinusoidal Endothelial Cell Differentiation and Liver Fibrosis in 129/Ola and C57BL/6 Mice. Cells. 2019;8: pubmed publisher
	Graf S, Haimel M, Bleda M, Hadinnapola C, Southgate L, Li W, et al. Identification of rare sequence variation underlying heritable pulmonary arterial hypertension. Nat Commun. 2018;9:1416 pubmed publisher
	Breitkopf Heinlein K, Meyer C, KÃ¶nig C, Gaitantzi H, Addante A, Thomas M, et al. BMP-9 interferes with liver regeneration and promotes liver fibrosis. Gut. 2017;66:939-954 pubmed publisher
	Ruiz S, Zhao H, Chandakkar P, Chatterjee P, Papoin J, Blanc L, et al. A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10. Sci Rep. 2016;5:37366 pubmed publisher
	Yoon B, Chung Y, Yoo S, Kawara K, Kim J, Yoo I, et al. Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis. J Biol Chem. 2016;291:4048-57 pubmed publisher
	Kienast Y, Jucknischke U, Scheiblich S, Thier M, de Wouters M, Haas A, et al. Rapid Activation of Bone Morphogenic Protein 9 by Receptor-mediated Displacement of Pro-domains. J Biol Chem. 2016;291:3395-410 pubmed publisher
	Chen J, Liu H, Liu J, Qi J, Wei B, Yang J, et al. H3K9 methylation is a barrier during somatic cell reprogramming into iPSCs. Nat Genet. 2013;45:34-42 pubmed publisher
	Ricard N, Ciais D, Levet S, Subileau M, Mallet C, Zimmers T, et al. BMP9 and BMP10 are critical for postnatal retinal vascular remodeling. Blood. 2012;119:6162-71 pubmed publisher
	van Meeteren L, Thorikay M, Bergqvist S, Pardali E, Stampino C, Hu Lowe D, et al. Anti-human activin receptor-like kinase 1 (ALK1) antibody attenuates bone morphogenetic protein 9 (BMP9)-induced ALK1 signaling and interferes with endothelial cell sprouting. J Biol Chem. 2012;287:18551-61 pubmed publisher
	Yao Y, Jumabay M, Ly A, Radparvar M, Wang A, Abdmaulen R, et al. Crossveinless 2 regulates bone morphogenetic protein 9 in human and mouse vascular endothelium. Blood. 2012;119:5037-47 pubmed publisher
	Herrera B, Inman G. A rapid and sensitive bioassay for the simultaneous measurement of multiple bone morphogenetic proteins. Identification and quantification of BMP4, BMP6 and BMP9 in bovine and human serum. BMC Cell Biol. 2009;10:20 pubmed publisher

product information

master code :

MAB3209

SKU :

MAB3209-100

product name :

Human/Mouse/Primate BMP-9 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human/Mouse/Primate BMP-9 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-9. This antibody reacts with human,mouse,primate,transgenic mouse. The Human/Mouse/Primate BMP-9 Antibody has been validated for the following applications: Neutralization,Western Blot,ELISA (detection),ELISA Development (Capture),ELISA Development (Detection),Immunoprecipitation,ELISA Capture,ELISA Capture (Matched Antibody Pair).

target :

BMP-9

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

360107

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human BMP-9, Ser320-Arg429, Accession # Q9UK05

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Primate,Transgenic Mouse

specificity :

Detects human and primate BMP-9 in ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human BMP-1, -1.1, -2, -3, -3b, -4, -5, -6, -7, -8, or -10 is observed. In direct ELISAs, approximately 80% cross-reactivity with recombinant mouse (rm) BMP-9 and 10% cross-reactivity with rmBMP-10 is observed.

gene symbol :

GDF2

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Alkaline Phosphatase Production Induced by BMP-9 and Neutralization by Human BMP-9 Antibody.

accessionNumbers :

Q9UK05

applications :

Neutralization,Western Blot,ELISA (detection),ELISA Development (Capture),ELISA Development (Detection),Immunoprecipitation,ELISA Capture,ELISA Capture (Matched Antibody Pair)

USD :

479 USD

alt names :

BMP9, BMP9BMP-9Bone morphogenetic protein 9, GDF2, GDF-2, growth differentiation factor 2, growth/differentiation factor 2

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage