Human CCL11/Eotaxin Antibody | R&D Systems MAB320-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL11/Eotaxin Antibody

catalog :

MAB320-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

43911

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Rump L, Mattey D, Kehoe O, Middleton J. An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine. 2017;97:133-140 pubmed publisher
Villeda S, Luo J, Mosher K, Zou B, Britschgi M, Bieri G, et al. The ageing systemic milieu negatively regulates neurogenesis and cognitive function. Nature. 2011;477:90-4 pubmed publisher
Miyagaki T, Sugaya M, Fujita H, Ohmatsu H, Kakinuma T, Kadono T, et al. Eotaxins and CCR3 interaction regulates the Th2 environment of cutaneous T-cell lymphoma. J Invest Dermatol. 2010;130:2304-11 pubmed publisher
Uller L, Emanuelsson C, Andersson M, Erjefalt J, Greiff L, Persson C. Early phase resolution of mucosal eosinophilic inflammation in allergic rhinitis. Respir Res. 2010;11:54 pubmed publisher
Osei Kumah A, Smith R, Clifton V. Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine. 2008;43:187-93 pubmed publisher
Miller M, Ramsdell J, Friedman P, Cho J, Renvall M, Broide D. Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J Allergy Clin Immunol. 2007;120:1118-25 pubmed
Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
Puxeddu I, Bader R, Piliponsky A, Reich R, Levi Schaffer F, Berkman N. The CC chemokine eotaxin/CCL11 has a selective profibrogenic effect on human lung fibroblasts. J Allergy Clin Immunol. 2006;117:103-10 pubmed
Hajnicka V, Vancova I, Kocakova P, Slovak M, Gasperík J, Slavikova M, et al. Manipulation of host cytokine network by ticks: a potential gateway for pathogen transmission. Parasitology. 2005;130:333-42 pubmed
Böttcher M, Jenmalm M, Bjorksten B, Garofalo R. Chemoattractant factors in breast milk from allergic and nonallergic mothers. Pediatr Res. 2000;47:592-7 pubmed

product information

brand :

R&D Systems

master code :

MAB320

SKU :

MAB320-100

product name :

Human CCL11/Eotaxin Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human CCL11/Eotaxin Antibody from R&D Systems is a mouse monoclonal antibody to CCL11/Eotaxin. This antibody reacts with human,mouse. The Human CCL11/Eotaxin Antibody has been validated for the following applications: ELISA Development,Neutralization,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunohistochemistry,Western Blot,ELISA Capture (Matched Antibody Pair),Dual RNAscope ISH-IHC Compatible.

target :

CCL11/Eotaxin

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS and NaCl with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

43911

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL, Neutralization 1-5 ug/mL, Dual RNAscope ISH-IHC 3-25 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL11/Eotaxin, Gly24-Pro97, Accession # P51671

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human CCL11/Eotaxin in ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant human CCL1, 2, 3, 4, 5, 7, 8, 9/10/MIP-1 gamma , 14, 17, 19, 20, 21, 25, recombinant mouse CCL2, 3, 4, 5,6, 7, 9/10/MIP-1 gamma , 11, 21, or 25.

gene symbol :

CCL11

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

CCL11/Eotaxin antibody in Human Colon by Immunohistochemistry (IHC-P).

accessionNumbers :

P51671

applications :

Immunohistochemistry,Western Blot,ELISA Capture (Matched Antibody Pair),Dual RNAscope ISH-IHC Compatible,ELISA Development,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization

USD :

469 USD

alt names :

C-C motif chemokine 11, chemokine (C-C motif) ligand 11, Eosinophil chemotactic protein, Eotaxin, eotaxin-1, MGC22554, SCYA11Small-inducible cytokine A11, small inducible cytokine subfamily A (Cys-Cys), member 11 (eotaxin)

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage