Human IL-17/IL-17A Antibody | R&D Systems MAB3171-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-17/IL-17A Antibody

catalog :

MAB3171-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

41802

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 11

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; fig 2c	Hawerkamp H, Domdey A, Radau L, Sewerin P, Oláh P, Homey B, et al. Tofacitinib downregulates antiviral immune defence in keratinocytes and reduces T cell activation. Arthritis Res Ther. 2021;23:144 pubmed publisher
	Lee A, Lee S, Choi J, Um I, Na H, Lee J, et al. Establishment of a humanized mouse model of keloid diseases following the migration of patient immune cells to the lesion: Patient-derived keloid xenograft (PDKX) model. Exp Mol Med. 2023;55:1713-1719 pubmed publisher
	Lee S, Lee A, Choi J, Lee C, Cho K, Lee J, et al. IL-17 Induces Autophagy Dysfunction to Promote Inflammatory Cell Death and Fibrosis in Keloid Fibroblasts via the STAT3 and HIF-1α Dependent Signaling Pathways. Front Immunol. 2022;13:888719 pubmed publisher
	Bolt J, van Kuijk A, Teunissen M, van der Coelen D, Aarrass S, Gerlag D, et al. Impact of Adalimumab Treatment on Interleukin-17 and Interleukin-17 Receptor Expression in Skin and Synovium of Psoriatic Arthritis Patients with Mild Psoriasis. Biomedicines. 2022;10: pubmed publisher
	Catar R, Bartosova M, Kawka E, Chen L, Marinovic I, Zhang C, et al. Angiogenic Role of Mesothelium-Derived Chemokine CXCL1 During Unfavorable Peritoneal Tissue Remodeling in Patients Receiving Peritoneal Dialysis as Renal Replacement Therapy. Front Immunol. 2022;13:821681 pubmed publisher
	Ismail M, Akefeldt S, Lourda M, Gavhed D, Gayet R, Arico M, et al. Comparison of three different ELISAs for the detection of recombinant, native and plasma IL-17A. MethodsX. 2020;7:100997 pubmed publisher
	Arampatzioglou A, Papazoglou D, Konstantinidis T, Chrysanthopoulou A, Mitsios A, Angelidou I, et al. Clarithromycin Enhances the Antibacterial Activity and Wound Healing Capacity in Type 2 Diabetes Mellitus by Increasing LL-37 Load on Neutrophil Extracellular Traps. Front Immunol. 2018;9:2064 pubmed publisher
	D Addio F, Vergani A, Potena L, Maestroni A, Usuelli V, Ben Nasr M, et al. P2X7R mutation disrupts the NLRP3-mediated Th program and predicts poor cardiac allograft outcomes. J Clin Invest. 2018;128:3490-3503 pubmed publisher
	Chan Y, Chen K, Duncan S, Lathrop K, Latoche J, Logar A, et al. Patients with cystic fibrosis have inducible IL-17+IL-22+ memory cells in lung draining lymph nodes. J Allergy Clin Immunol. 2013;131:1117-29, 1129.e1-5 pubmed publisher
	Nakashima T, Jinnin M, Yamane K, Honda N, Kajihara I, Makino T, et al. Impaired IL-17 signaling pathway contributes to the increased collagen expression in scleroderma fibroblasts. J Immunol. 2012;188:3573-83 pubmed publisher
	Coury F, Annels N, Rivollier A, Olsson S, Santoro A, Speziani C, et al. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion. Nat Med. 2008;14:81-7 pubmed

product information

master code :

MAB3171

SKU :

MAB3171-100

product name :

Human IL-17/IL-17A Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human IL-17/IL-17A Antibody from R&D Systems is a mouse monoclonal antibody to IL-17/IL-17A. This antibody reacts with human,mouse. The Human IL-17/IL-17A Antibody has been validated for the following applications: Western Blot,Immunocytochemistry,Confocal Imaging,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

IL-17/IL-17A

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

41802

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-17, Ile20-Ala155, Accession # Q16552

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human IL-17 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) IL-17A/IL-17F heterodimer is observed. No cross-reactivity with recombinant mouse IL-17, recombinant canine Il-17, rhIL-17B, rhIL-17C, rhIL-17D, rhIL-17E, or rhIL-17F is observed.

gene symbol :

IL17A

top caption :

Detection of IL-17/IL-17A Mouse antibody by Western Blot.

accessionNumbers :

Q16552

applications :

Western Blot,Immunocytochemistry,Confocal Imaging,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunoprecipitation,Intracellular Staining by Flow Cytometry,CyTOF-ready

USD :

469 USD

alt names :

CTLA8, CTLA-8, CTLA8cytotoxic T-lymphocyte-associated serine esterase 8, Cytotoxic T-lymphocyte-associated antigen 8, IL17, IL17A, IL-17A, IL-17Acytotoxic T-lymphocyte-associated protein 8, IL-17CTLA-8, IL17interleukin-17A, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8), interleukin 17A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage