product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ROBO2 Antibody
catalog :
MAB3147
quantity :
100 ug (also 25 ug)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
356001
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry
more info or order :
citations: 6
Reference
Li Q, Cui S, Ma Q, Liu Y, Yu H, Geng G, et al. Disruption of Robo2-Baiap2 integrated signaling drives cystic disease. JCI Insight. 2019;4: pubmed publisher
Johnson V, Junge H, Chen Z. Temporal regulation of axonal repulsion by alternative splicing of a conserved microexon in mammalian Robo1 and Robo2. elife. 2019;8: pubmed publisher
Fan X, Yang H, Kumar S, Tumelty K, Pisarek Horowitz A, Rasouly H, et al. SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016;1:e86934 pubmed publisher
Xie X, Tsai S, Tsai M. COUP-TFII regulates satellite cell function and muscular dystrophy. J Clin Invest. 2016;126:3929-3941 pubmed publisher
Xu F, Wu L, Chang C, He Q, Zhang Z, Liu L, et al. Whole-exome and targeted sequencing identify ROBO1 and ROBO2 mutations as progression-related drivers in myelodysplastic syndromes. Nat Commun. 2015;6:8806 pubmed publisher
Guijarro Muñoz I, Cuesta A, Alvarez Cienfuegos A, Geng J, Alvarez Vallina L, Sanz L. The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis. Exp Cell Res. 2012;318:371-8 pubmed publisher
product information
brand :
R&D Systems
master code :
MAB3147
SKU :
MAB3147
product name :
Human ROBO2 Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human ROBO2 Antibody from R&D Systems is a mouse monoclonal antibody to ROBO2. This antibody reacts with human,mouse. The Human ROBO2 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Immunohistochemistry,Western Blot,CyTOF-ready.
target :
ROBO2
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
356001
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, CyTOF-ready
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ROBO2 isoform 1, Ser22-Pro859, Accession # Q9HCK4.2
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human ROBO2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ROBO1, rhROBO3, or rhROBO4 is observed.
gene symbol :
ROBO2
top caption :
Detection of ROBO2 antibody in HEK293 Human Cell Line transfected with Human ROBO2 and eGFP antibody by Flow Cytometry.
accessionNumbers :
Q9HCK4.2
applications :
Western Blot,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Immunoprecipitation
USD :
429 USD
alt names :
Drosophila) homolog 2, roundabout, axon guidance receptor, homolog 2 (Drosophila), SAX3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.