Human Tie-2 Antibody | R&D Systems MAB313 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Tie-2 Antibody

catalog :

MAB313

quantity :

500 ug (also 25 ug)

price :

499 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

83711

reactivity :

human

application :

western blot

more info or order :

R&D Systems product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human	Meissner M, Reichenbach G, Stein M, Hrgovic I, Kaufmann R, Gille J. Down-regulation of vascular endothelial growth factor receptor 2 is a major molecular determinant of proteasome inhibitor-mediated antiangiogenic action in endothelial cells. Cancer Res. 2009;69:1976-84 pubmed publisher
western blot; human	Giuliani N, Colla S, Lazzaretti M, Sala R, Roti G, Mancini C, et al. Proangiogenic properties of human myeloma cells: production of angiopoietin-1 and its potential relationship to myeloma-induced angiogenesis. Blood. 2003;102:638-45 pubmed
	Faes S, Uldry E, Planche A, Santoro T, Pythoud C, Demartines N, et al. Acidic pH reduces VEGF-mediated endothelial cell responses by downregulation of VEGFR-2; relevance for anti-angiogenic therapies. Oncotarget. 2016;7:86026-86038 pubmed publisher
	Shi E, Fury W, Li W, Mikulka W, Aldrich T, Rafique A, et al. Monoclonal antibody classification based on epitope-binding using differential antigen disruption. J Immunol Methods. 2006;314:9-20 pubmed

product information

master code :

MAB313

SKU :

MAB313

product name :

Human Tie-2 Antibody

unit size :

500 ug (also 25 ug)

description :

The Human Tie-2 Antibody from R&D Systems is a mouse monoclonal antibody to Tie-2. This antibody reacts with human. The Human Tie-2 Antibody has been validated for the following applications: Biacore Binding Assay,Epitope Mapping,Western Blot.

target :

Tie-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

83711

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human Tie-2, Ala23-Lys745, Accession # AAA61139

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human Tie-2 in direct ELISAs and Western blots. Shows approximately 15% cross-reactivity with recombinant mouse Tie-2 and less than 1% cross-reactivity with recombinant human Tie-1.

gene symbol :

TEK

accessionNumbers :

AAA61139

applications :

Biacore Binding Assay,Epitope Mapping,Western Blot

USD :

499 USD

alt names :

angiopoietin-1 receptor, CD202B, CD202b antigen, EC 2.7.10, EC 2.7.10.1, hTIE2, p140 TEK, soluble TIE2 variant 1, soluble TIE2 variant 2, TEK, TEK tyrosine kinase, endothelial, Tie2, TIE-2, TIE2CD202b, Tunica interna endothelial cell kinase, Tyrosine-protein kinase receptor TEK, Tyrosine-protein kinase receptor TIE-2, venous malformations, multiple cutaneous and mucosal, VMCM, VMCM1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage