product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse S100A8 Antibody
catalog :
MAB3059
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
335806
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 13
Reference
Lindquist K, Shein S, Hovhannisyan A, Mecklenburg J, Zou Y, Lai Z, et al. Associations of tissue damage induced inflammatory plasticity in masseter muscle with the resolution of chronic myalgia. Sci Rep. 2023;13:22057 pubmed publisher
Zhao N, Kabotyanski E, Saltzman A, Malovannaya A, Yuan X, Reineke L, et al. Targeting EIF4A triggers an interferon response to synergize with chemotherapy and suppress triple-negative breast cancer. bioRxiv. 2023;: pubmed publisher
Pavlenko D, Todurga Seven Z, Bystrom L, Markan A, Verpile R, Ishida H, et al. Crisaborole Inhibits Itch and Pain by Preventing Neutrophil Infiltration in a Mouse Model of Atopic Dermatitis. Acta Derm Venereol. 2023;103:adv13382 pubmed publisher
Janghorban M, Yang Y, Zhao N, Hamor C, Nguyen T, Zhang X, et al. Single-Cell Analysis Unveils the Role of the Tumor Immune Microenvironment and Notch Signaling in Dormant Minimal Residual Disease. Cancer Res. 2022;82:885-899 pubmed publisher
Shi Z, Mori Akiyama Y, Du W, Fultz R, Zhao Y, Ruan W, et al. Loss of H2R Signaling Disrupts Neutrophil Homeostasis and Promotes Inflammation-Associated Colonic Tumorigenesis in Mice. Cell Mol Gastroenterol Hepatol. 2022;13:717-737 pubmed publisher
Sinha V, Rinkenbaugh A, Xu M, Zhou X, Zhang X, Jeter Jones S, et al. Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast. Nat Commun. 2021;12:5024 pubmed publisher
Davison L, Alberto A, Dand H, Keller E, Patt M, Khan A, et al. S100a9 Protects Male Lupus-Prone NZBWF1 Mice From Disease Development. Front Immunol. 2021;12:681503 pubmed publisher
Kim S, García Recio S, Creighton C, Perou C, Rosen J. Alterations in Wnt- and/or STAT3 signaling pathways and the immune microenvironment during metastatic progression. Oncogene. 2019;38:5942-5958 pubmed publisher
Makthal N, Nguyen K, Do H, Gavagan M, Chandrangsu P, Helmann J, et al. A Critical Role of Zinc Importer AdcABC in Group A Streptococcus-Host Interactions During Infection and Its Implications for Vaccine Development. EBioMedicine. 2017;21:131-141 pubmed publisher
Sekimoto R, Fukuda S, Maeda N, Tsushima Y, Matsuda K, Mori T, et al. Visualized macrophage dynamics and significance of S100A8 in obese fat. Proc Natl Acad Sci U S A. 2015;112:E2058-66 pubmed publisher
Dessing M, Tammaro A, Pulskens W, Teske G, Butter L, Claessen N, et al. The calcium-binding protein complex S100A8/A9 has a crucial role in controlling macrophage-mediated renal repair following ischemia/reperfusion. Kidney Int. 2015;87:85-94 pubmed publisher
Yano J, Kolls J, Happel K, WORMLEY F, Wozniak K, Fidel P. The acute neutrophil response mediated by S100 alarmins during vaginal Candida infections is independent of the Th17-pathway. PLoS ONE. 2012;7:e46311 pubmed publisher
Dessing M, Butter L, Teske G, Claessen N, van der Loos C, Vogl T, et al. S100A8/A9 is not involved in host defense against murine urinary tract infection. PLoS ONE. 2010;5:e13394 pubmed publisher
product information
master code :
MAB3059
SKU :
MAB3059
product name :
Mouse S100A8 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse S100A8 Antibody from R&D Systems is a rat monoclonal antibody to S100A8. This antibody reacts with human,mouse,transgenic mouse. The Mouse S100A8 Antibody has been validated for the following applications: Immunohistochemistry,ELISA Development,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
S100A8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
335806
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
E. coli -derived recombinant mouse S100A8, Met1-Glu89 (predicted), Accession # P27005
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Transgenic Mouse
specificity :
Detects mouse S100A8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 40% cross-reactivity with recombinant human (rh) S100A8 is observed and no cross-reactivity with recombinant mouse (rm) S100A4, rmS100A9, rmS100A10, rmS100A11, rhS100B, or rhS100P is observed.
gene symbol :
S100A8
top caption :
Detection of S100A8 Rat antibody by Western Blot.
accessionNumbers :
P27005
applications :
Immunohistochemistry,ELISA Development,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry
USD :
479 USD
alt names :
60B8AG, CAGACP-10, calgranulin A, Calgranulin-A, Calprotectin L1L subunit, CFAG, CFAGL1Ag, CGLA, Cystic fibrosis antigen, Leukocyte L1 complex light chain, MA387, MIF, Migration inhibitory factor-related protein 8, MRP8, MRP-8, MRP8S100 calcium binding protein A8 (calgranulin A), NIF, P8, protein S100-A8, S100 calcium binding protein A8, S100 calcium-binding protein A8, S100 calcium-binding protein A8 (calgranulin A), Urinary stone protein band A
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.