Human IL-4 Antibody | R&D Systems MAB304-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-4 Antibody

catalog :

MAB304-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3007

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 12

Reference
Mehrara B, Park H, Kataru R, Bromberg J, Coriddi M, Baik J, et al. Pilot Study of Anti-Th2 Immunotherapy for the Treatment of Breast Cancer-Related Upper Extremity Lymphedema. Biology (Basel). 2021;10: pubmed publisher
Huanosta Murillo E, Alc xe1 ntara Hern xe1 ndez M, Hern xe1 ndez Rico B, Victoria Acosta G, Miranda Cruz P, Dom xed nguez G xf3 mez M, et al. NLRP3 Regulates IL-4 Expression in TOX+ CD4+ T Cells of Cutaneous T Cell Lymphoma to Potentially Promote Disease Progression. Front Immunol. 2021;12:668369 pubmed publisher
Conde E, Bertrand R, Balbino B, Bonnefoy J, Stackowicz J, Caillot N, et al. Dual vaccination against IL-4 and IL-13 protects against chronic allergic asthma in mice. Nat Commun. 2021;12:2574 pubmed publisher
Maehara T, Munemura R, Shimizu M, Kakizoe N, Kaneko N, Murakami Y, et al. Tissue-infiltrating immune cells contribute to understanding the pathogenesis of Kimura disease: A case report. Medicine (Baltimore). 2019;98:e18300 pubmed publisher
Ricciardi S, Manfrini N, Alfieri R, Calamita P, Crosti M, Gallo S, et al. The Translational Machinery of Human CD4+ T Cells Is Poised for Activation and Controls the Switch from Quiescence to Metabolic Remodeling. Cell Metab. 2018;28:895-906.e5 pubmed publisher
Maehara T, Mattoo H, Mahajan V, Murphy S, Yuen G, Ishiguro N, et al. The expansion in lymphoid organs of IL-4+ BATF+ T follicular helper cells is linked to IgG4 class switching in vivo. Life Sci Alliance. 2018;1: pubmed publisher
Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal R, Curti S, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015;16:318-325 pubmed publisher
Assirelli E, Pulsatelli L, Dolzani P, Platano D, Olivotto E, Filardo G, et al. Human osteoarthritic cartilage shows reduced in vivo expression of IL-4, a chondroprotective cytokine that differentially modulates IL-1?-stimulated production of chemokines and matrix-degrading enzymes in vitro. PLoS ONE. 2014;9:e96925 pubmed publisher
Nagy N, Adori M, Rasul A, Heuts F, Salamon D, Ujvári D, et al. Soluble factors produced by activated CD4+ T cells modulate EBV latency. Proc Natl Acad Sci U S A. 2012;109:1512-7 pubmed publisher
Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, et al. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes. J Immunol. 2010;184:4880-8 pubmed publisher
Miller M, Ramsdell J, Friedman P, Cho J, Renvall M, Broide D. Computed tomographic scan-diagnosed chronic obstructive pulmonary disease-emphysema: eotaxin-1 is associated with bronchodilator response and extent of emphysema. J Allergy Clin Immunol. 2007;120:1118-25 pubmed
Aoudjehane L, Podevin P, Scatton O, Jaffray P, Dusanter Fourt I, Feldmann G, et al. Interleukin-4 induces human hepatocyte apoptosis through a Fas-independent pathway. FASEB J. 2007;21:1433-44 pubmed

product information

brand :

R&D Systems

master code :

MAB304

SKU :

MAB304-100

product name :

Human IL-4 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human IL-4 Antibody from R&D Systems is a mouse monoclonal antibody to IL-4. This antibody reacts with human,mouse. The Human IL-4 Antibody has been validated for the following applications: Neutralization,ELISA Capture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Western Blot,Immunocytochemistry.

target :

IL-4

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

3007

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Neutralization 0.03-0.1 ug/mL, Immunocytochemistry 8-25 ug/mL

host :

Mouse

immunogen :

E. coli -derived recombinant human IL-4, His25-Ser153, Accession # P05112.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human,Mouse

specificity :

Detects human IL-4 in direct ELISAs and Western blots. In Western blots, this antibody does not cross-react with recombinant mouse IL-4.

gene symbol :

IL4

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

IL-4 antibody in Human PBMCs by Immunocytochemistry (ICC).

accessionNumbers :

P05112.1

applications :

Western Blot,Immunocytochemistry,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,ELISA Capture

USD :

489 USD

alt names :

B cell growth factor 1, BCDF, B-cell stimulatory factor 1, BCGF1, BCGF-1, binetrakin, BSF1, BSF-1, IL4, IL-4B_cell stimulatory factor 1, IL4E12, interleukin 4, interleukin-4, Lymphocyte stimulatory factor 1, MGC79402, Pitrakinra

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage