This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human IL-3R alpha/CD123 Antibody
catalog :
MAB301
quantity :
100 ug (also 25 ug, 500 ug)
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32703
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry
citations: 6
Reference
Chen J, Kao Y, Sun D, Todorova T, Reynolds D, Narayanagari S, et al. Myelodysplastic syndrome progression to acute myeloid leukemia at the stem cell level. Nat Med. 2019;25:103-110 pubmed publisher
Broughton S, Hercus T, Nero T, Kan W, Barry E, Dottore M, et al. A dual role for the N-terminal domain of the IL-3 receptor in cell signalling. Nat Commun. 2018;9:386 pubmed publisher
Barhanpurkar Naik A, Mhaske S, Pote S, Singh K, Wani M. Interleukin-3 enhances the migration of human mesenchymal stem cells by regulating expression of CXCR4. Stem Cell Res Ther. 2017;8:168 pubmed publisher
Dijkstra D, Meyer Bahlburg A. Human Basophils Modulate Plasma Cell Differentiation and Maturation. J Immunol. 2017;198:229-238 pubmed
Leskela S, Serrano A, de la Fuente H, Rodríguez Muñoz A, Ramos Levi A, Sampedro Nuñez M, et al. Graves' disease is associated with a defective expression of the immune regulatory molecule galectin-9 in antigen-presenting dendritic cells. PLoS ONE. 2015;10:e0123938 pubmed publisher
Bovolenta C, Pilotti E, Mauri M, Turci M, Ciancianaini P, Fisicaro P, et al. Human T-cell leukemia virus type 2 induces survival and proliferation of CD34(+) TF-1 cells through activation of STAT1 and STAT5 by secretion of interferon-gamma and granulocyte macrophage-colony-stimulating factor. Blood. 2002;99:224-31 pubmed
product information
brand :
R&D Systems
master code :
MAB301
SKU :
MAB301-100
product name :
Human IL-3R alpha/CD123 Antibody
description :
The Human IL-3R alpha/CD123 Antibody from R&D Systems is a mouse monoclonal antibody to IL-3R alpha/CD123. This antibody reacts with human. The Human IL-3R alpha/CD123 Antibody has been validated for the following applications: Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready.
target :
IL-3R alpha/CD123
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
32703
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-3 R alpha/CD123, Lys20-Arg305, predicted, Accession # P26951
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human IL-3 R alpha/CD123 in direct ELISAs and Western blots.
gene symbol :
IL3RA
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB301
accessionNumbers :
P26951
applications :
Western Blot, Flow Cytometry, Immunohistochemistry, Neutralization, Immunocytochemistry, CyTOF-ready
2020 USD :
339
2021 USD :
369 USD
alt names :
CD123, CD123 antigen, hIL3Ra, hIL-3Ra, IL-3 R alpha, IL-3 receptor subunit alpha, IL3R, IL3R alpha, IL-3R subunit alpha, IL3RA, IL-3RA, IL-3R-alpha, IL3RAY, IL3RX, IL3RY, interleukin 3 receptor, alpha (low affinity), interleukin-3 receptor subunit alpha, MGC34174
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.