product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Primate VEGF Antibody
catalog :
MAB293-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
509 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
26503
reactivity :
human, mouse, rat, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 113
Published Application/Species/Sample/DilutionReference
  • western blot; rat; 1:750; loading ...; fig 9d
Abu El Asrar A, Nawaz M, Ahmad A, Siddiquei M, Allegaert E, Gikandi P, et al. CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy. Invest Ophthalmol Vis Sci. 2021;62:32 pubmed publisher
Lim S, Gan S, Ong H, Ngeow Y. In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue. Biochem Biophys Rep. 2024;39:101814 pubmed publisher
Harary S xf8 ndergaard R, Drozd H xf8 jgaard L, Haack S xf8 rensen M, Hoeeg C, M xf8 nsted Johansen E, Follin B, et al. Investigating the paracrine and juxtacrine abilities of adipose-derived stromal cells in angiogenesis triple cell co-cultures. Stem Cell Res. 2024;77:103417 pubmed publisher
Dutta Gupta S, Ta M. ADAMTS13 regulates angiogenic markers via Ephrin/Eph signaling in human mesenchymal stem cells under serum-deprivation stress. Sci Rep. 2024;14:560 pubmed publisher
Urban L, Nov xe1 k x, x10c oma M, Dvo x159 xe1 nkov xe1 B, Lacina L, x160 xe1 chov xe1 J, et al. Unravelling heterogeneous effects of cancer‑associated fibroblasts on poor prognosis markers in breast cancer EM‑G3 cell line: In vitro‑targeted treatment (anti‑IL-6, anti‑VEGF-A, anti‑MFGE8) based on tr. Oncol Rep. 2024;51: pubmed publisher
Abu El Asrar A, Nawaz M, Ahmad A, Dillemans L, Siddiquei M, Allegaert E, et al. CD40 Ligand-CD40 Interaction Is an Intermediary between Inflammation and Angiogenesis in Proliferative Diabetic Retinopathy. Int J Mol Sci. 2023;24: pubmed publisher
Wong S, Tey S, Mao X, Fung H, Xiao Z, Wong D, et al. Small Extracellular Vesicle-Derived vWF Induces a Positive Feedback Loop between Tumor and Endothelial Cells to Promote Angiogenesis and Metastasis in Hepatocellular Carcinoma. Adv Sci (Weinh). 2023;10:e2302677 pubmed publisher
Gatina D, Gazizov I, Zhuravleva M, Arkhipova S, Golubenko M, Gomzikova M, et al. Induction of Angiogenesis by Genetically Modified Human Umbilical Cord Blood Mononuclear Cells. Int J Mol Sci. 2023;24: pubmed publisher
Peng N, Kang H, Feng Y, Minikes A, Jiang X. Autophagy inhibition signals through senescence to promote tumor suppression. Autophagy. 2022;:1-17 pubmed publisher
Kunimatsu R, Hiraki T, Rikitake K, Nakajima K, Putranti N, Abe T, et al. Effects of Human Deciduous Dental Pulp-Derived Mesenchymal Stem Cell-Derived Conditioned Medium on the Metabolism of HUVECs, Osteoblasts, and BMSCs. Cells. 2022;11: pubmed publisher
Weigert A, Zheng X, Nenzel A, Turkowski K, G xfc nther S, Strack E, et al. Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system. Nat Commun. 2022;13:6078 pubmed publisher
Park H, Nam K, Lee H, Kim K. Ionizing Radiation-Induced GDF15 Promotes Angiogenesis in Human Glioblastoma Models by Promoting VEGFA Expression Through p-MAPK1/SP1 Signaling. Front Oncol. 2022;12:801230 pubmed publisher
Okikawa S, Morine Y, Saito Y, Yamada S, Tokuda K, Teraoku H, et al. Inhibition of the VEGF signaling pathway attenuates tumor‑associated macrophage activity in liver cancer. Oncol Rep. 2022;47: pubmed publisher
Abu El Asrar A, Ahmad A, Nawaz M, Siddiquei M, De Zutter A, Vanbrabant L, et al. Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation. Front Physiol. 2021;12:807747 pubmed publisher
Keil V, Gielen G, Pintea B, Baumgarten P, Datsi A, Hittatiya K, et al. DCE-MRI in Glioma, Infiltration Zone and Healthy Brain to Assess Angiogenesis: A Biopsy Study. Clin Neuroradiol. 2021;31:1049-1058 pubmed publisher
Manian K, Galloway C, Dalvi S, Emanuel A, Mereness J, Black W, et al. 3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration. Cell Stem Cell. 2021;28:846-862.e8 pubmed publisher
Abu El Asrar A, Nawaz M, Ahmad A, De Zutter A, Siddiquei M, Blanter M, et al. Evaluation of Proteoforms of the Transmembrane Chemokines CXCL16 and CX3CL1, Their Receptors, and Their Processing Metalloproteinases ADAM10 and ADAM17 in Proliferative Diabetic Retinopathy. Front Immunol. 2020;11:601639 pubmed publisher
Bernatz S, Monden D, Gessler F, Radic T, Hattingen E, Senft C, et al. Influence of VEGF-A, VEGFR-1-3, and neuropilin 1-2 on progression-free: and overall survival in WHO grade II and III meningioma patients. J Mol Histol. 2021;52:233-243 pubmed publisher
Liao Z, Liang I, Li H, Wu C, Lo H, Chang D, et al. Chrysin Inhibits High Glucose-Induced Migration on Chorioretinal Endothelial Cells via VEGF and VEGFR Down-Regulation. Int J Mol Sci. 2020;21: pubmed publisher
Lee J, Tatsumi A, Tsukakoshi K, Wilson E, Abe K, Sode K, et al. Application of a Glucose Dehydrogenase-Fused with Zinc Finger Protein to Label DNA Aptamers for the Electrochemical Detection of VEGF. Sensors (Basel). 2020;20: pubmed publisher
Chang Z, Zhang Y, Liu J, Zheng Y, Li H, Kong Y, et al. Snail promotes the generation of vascular endothelium by breast cancer cells. Cell Death Dis. 2020;11:457 pubmed publisher
Oh H, Kwak J, Kim B, Jin H, Park W, Choi S, et al. Migration Inhibitory Factor in Conditioned Medium from Human Umbilical Cord Blood-Derived Mesenchymal Stromal Cells Stimulates Hair Growth. Cells. 2020;9: pubmed publisher
Perdicaro D, Rodriguez Lanzi C, Gambarte Tudela J, Miatello R, Oteiza P, Vazquez Prieto M. Quercetin attenuates adipose hypertrophy, in part through activation of adipogenesis in rats fed a high-fat diet. J Nutr Biochem. 2020;79:108352 pubmed publisher
Wang R, Ma Y, Zhan S, Zhang G, Cao L, Zhang X, et al. B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expression. Cell Death Dis. 2020;11:55 pubmed publisher
Abu El Asrar A, Ahmad A, Siddiquei M, De Zutter A, Allegaert E, Gikandi P, et al. The Proinflammatory and Proangiogenic Macrophage Migration Inhibitory Factor Is a Potential Regulator in Proliferative Diabetic Retinopathy. Front Immunol. 2019;10:2752 pubmed publisher
Ko S, Lee W, Kenny H, Dang L, Ellis L, Jonasch E, et al. Cancer-derived small extracellular vesicles promote angiogenesis by heparin-bound, bevacizumab-insensitive VEGF, independent of vesicle uptake. Commun Biol. 2019;2:386 pubmed publisher
Stassi A, Gasser F, Velázquez M, Belotti E, Gareis N, Rey F, et al. Contribution of the VEGF system to the follicular persistence associated with bovine cystic ovaries. Theriogenology. 2019;138:52-65 pubmed publisher
Little A, Pathanjeli P, Wu Z, Bao L, Goo L, Yates J, et al. IL-4/IL-13 Stimulated Macrophages Enhance Breast Cancer Invasion Via Rho-GTPase Regulation of Synergistic VEGF/CCL-18 Signaling. Front Oncol. 2019;9:456 pubmed publisher
Jia J, Zhang H, Zhang H, Du H, Liu W, Shu M. Activated androgen receptor accelerates angiogenesis in cutaneous neurofibroma by regulating VEGFA transcription. Int J Oncol. 2019;55:157-166 pubmed publisher
Ren J, Gu C, Yang Y, Xue J, Sun Y, Jian F, et al. TSP-1 is downregulated and inversely correlates with miR-449c expression in Cushing's disease. J Cell Mol Med. 2019;23:4097-4110 pubmed publisher
Sumner G, Georgaros C, Rafique A, DiCioccio T, Martin J, Papadopoulos N, et al. Anti-VEGF drug interference with VEGF quantitation in the R&D systems human quantikine VEGF ELISA kit. Bioanalysis. 2019;11:381-392 pubmed publisher
Zizza P, Dinami R, Porru M, Cingolani C, Salvati E, Rizzo A, et al. TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment. Nucleic Acids Res. 2019;47:3365-3382 pubmed publisher
Grun D, Adhikary G, Eckert R. NRP-1 interacts with GIPC1 and SYX to activate p38 MAPK signaling and cancer stem cell survival. Mol Carcinog. 2018;: pubmed publisher
Kim H, Lee S, Lee S, Oh B, Kim J, Kim J, et al. A Subset of Paracrine Factors as Efficient Biomarkers for Predicting Vascular Regenerative Efficacy of Mesenchymal Stromal/Stem Cells. Stem Cells. 2019;37:77-88 pubmed publisher
Stein J, Xu Q, Jackson K, Romm E, Wuest S, Kosa P, et al. Intrathecal B Cells in MS Have Significantly Greater Lymphangiogenic Potential Compared to B Cells Derived From Non-MS Subjects. Front Neurol. 2018;9:554 pubmed publisher
Zhao Y, Song J, Bi X, Gao J, Shen Z, Zhu J, et al. Thymosin β4 promotes endothelial progenitor cell angiogenesis via a vascular endothelial growth factor‑dependent mechanism. Mol Med Rep. 2018;18:2314-2320 pubmed publisher
Tang M, Yue P, Ip P, Huang R, Lai H, Cheung A, et al. Soluble E-cadherin promotes tumor angiogenesis and localizes to exosome surface. Nat Commun. 2018;9:2270 pubmed publisher
Rodriguez Lanzi C, Perdicaro D, Landa M, Fontana A, Antoniolli A, Miatello R, et al. Grape pomace extract induced beige cells in white adipose tissue from rats and in 3T3-L1 adipocytes. J Nutr Biochem. 2018;56:224-233 pubmed publisher
Rao L, De Veirman K, Giannico D, Saltarella I, Desantis V, Frassanito M, et al. Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin® protein MP0250: a preclinical study. Oncotarget. 2018;9:13366-13381 pubmed publisher
Xu X, Cui N, Wang E. Application of an acellular dermal matrix to a rabbit model of oral mucosal defects. Exp Ther Med. 2018;15:2450-2456 pubmed publisher
Gogalic S, Sauer U, Doppler S, Preininger C. Investigating Colorimetric Protein Array Assay Schemes for Detection of Recurrence of Bladder Cancer. Biosensors (Basel). 2018;8: pubmed publisher
Biselli Chicote P, Biselli J, Cunha B, Castro R, Maniglia J, Neto D, et al. Overexpression of Antiangiogenic Vascular Endothelial Growth Factor Isoform and Splicing Regulatory Factors in Oral, Laryngeal and Pharyngeal Squamous Cell Carcinomas. Asian Pac J Cancer Prev. 2017;18:2171-2177 pubmed
Konen J, Summerbell E, Dwivedi B, Galior K, Hou Y, Rusnak L, et al. Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion. Nat Commun. 2017;8:15078 pubmed publisher
McDonald G, Tabellini L, Storer B, Martin P, Lawler R, Rosinski S, et al. Predictive Value of Clinical Findings and Plasma Biomarkers after Fourteen Days of Prednisone Treatment for Acute Graft-versus-host Disease. Biol Blood Marrow Transplant. 2017;23:1257-1263 pubmed publisher
Strickland Marmol L, Brem S, Rojiani A, Rojiani M. Vessel morphometric parameters-correlation with histologic grade and VEGF expression in oligodendroglioma. Am J Cancer Res. 2017;7:973-981 pubmed
Wang P, Lan C, Xiong S, Zhao X, Shan Y, Hu R, et al. HIF1α regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia. Oncotarget. 2017;8:28074-28092 pubmed publisher
Katagiri W, Kawai T, Osugi M, Sugimura Wakayama Y, Sakaguchi K, Kojima T, et al. Angiogenesis in newly regenerated bone by secretomes of human mesenchymal stem cells. Maxillofac Plast Reconstr Surg. 2017;39:8 pubmed publisher
Thej C, Ramadasse B, Walvekar A, Majumdar A, Balasubramanian S. Development of a surrogate potency assay to determine the angiogenic activity of Stempeucel®, a pooled, ex-vivo expanded, allogeneic human bone marrow mesenchymal stromal cell product. Stem Cell Res Ther. 2017;8:47 pubmed publisher
Ebrahim N, Leach L. Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: Junctional dynamics and putative mechanisms. Placenta. 2016;48:87-98 pubmed publisher
Amara S, Alotaibi D, Tiriveedhi V. NFAT5/STAT3 interaction mediates synergism of high salt with IL-17 towards induction of VEGF-A expression in breast cancer cells. Oncol Lett. 2016;12:933-943 pubmed
Liu L, Jiang Y, Steinle J. Compound 49b Restores Retinal Thickness and Reduces Degenerate Capillaries in the Rat Retina following Ischemia/Reperfusion. PLoS ONE. 2016;11:e0159532 pubmed publisher
Abu El Asrar A, Alam K, Nawaz M, Mohammad G, Van den Eynde K, Siddiquei M, et al. Upregulation of Thrombin/Matrix Metalloproteinase-1/Protease-Activated Receptor-1 Chain in Proliferative Diabetic Retinopathy. Curr Eye Res. 2016;41:1590-1600 pubmed
Jinesh G, Kamat A. Endocytosis and serpentine filopodia drive blebbishield-mediated resurrection of apoptotic cancer stem cells. Cell Death Discov. 2016;2: pubmed
Zhang X, Cao J, Pei Y, Zhang J, Wang Q. Smad4 inhibits cell migration via suppression of JNK activity in human pancreatic carcinoma PANC-1 cells. Oncol Lett. 2016;11:3465-3470 pubmed
Jing Z, Xu H, Chen X, Zhong Q, Huang J, Zhang Y, et al. The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer. PLoS ONE. 2016;11:e0152789 pubmed publisher
Zhang Y, Liu J, Wang S, Luo X, Li Y, Lv Z, et al. The DEK oncogene activates VEGF expression and promotes tumor angiogenesis and growth in HIF-1α-dependent and -independent manners. Oncotarget. 2016;7:23740-56 pubmed publisher
Zhao Z, Li J, Ye R, Wu X, Gao L, Niu B. Interleukin-6 as a potential molecular target in esophageal squamous cell carcinoma. Oncol Lett. 2016;11:925-932 pubmed
Zhao L, Liu H, Wei Q, Xu G, Wu J, Xu H, et al. Contrast-Enhanced Ultrasonography Features of Breast Malignancies with Different Sizes: Correlation with Prognostic Factors. Biomed Res Int. 2015;2015:613831 pubmed publisher
Zhang Y, Liu J, Lin J, Zhou L, Song Y, Wei B, et al. The transcription factor GATA1 and the histone methyltransferase SET7 interact to promote VEGF-mediated angiogenesis and tumor growth and predict clinical outcome of breast cancer. Oncotarget. 2016;7:9859-75 pubmed publisher
Grün D, Adhikary G, Eckert R. VEGF-A acts via neuropilin-1 to enhance epidermal cancer stem cell survival and formation of aggressive and highly vascularized tumors. Oncogene. 2016;35:4379-87 pubmed publisher
Nalwoga H, Ahmed L, Arnes J, Wabinga H, Akslen L. Strong Expression of Hypoxia-Inducible Factor-1α (HIF-1α) Is Associated with Axl Expression and Features of Aggressive Tumors in African Breast Cancer. PLoS ONE. 2016;11:e0146823 pubmed publisher
Gao Y, Wu K, Chen Y, Zhou J, Du C, Shi Q, et al. Beyond proliferation: KLF5 promotes angiogenesis of bladder cancer through directly regulating VEGFA transcription. Oncotarget. 2015;6:43791-805 pubmed publisher
Mar A, Chu C, Lee H, Chien C, Cheng J, Yang S, et al. Interleukin-1 Receptor Type 2 Acts with c-Fos to Enhance the Expression of Interleukin-6 and Vascular Endothelial Growth Factor A in Colon Cancer Cells and Induce Angiogenesis. J Biol Chem. 2015;290:22212-24 pubmed publisher
Bai Y, Zhu X, Chao J, Zhang Y, Qian C, Li P, et al. Pericytes contribute to the disruption of the cerebral endothelial barrier via increasing VEGF expression: implications for stroke. PLoS ONE. 2015;10:e0124362 pubmed publisher
Cai H, Xue Y, Li Z, Hu Y, Wang Z, Liu W, et al. Roundabout4 suppresses glioma-induced endothelial cell proliferation, migration and tube formation in vitro by inhibiting VEGR2-mediated PI3K/AKT and FAK signaling pathways. Cell Physiol Biochem. 2015;35:1689-705 pubmed publisher
Yuan F, Shi H, Ji J, Cai Q, Chen X, Yu Y, et al. Capecitabine metronomic chemotherapy inhibits the proliferation of gastric cancer cells through anti-angiogenesis. Oncol Rep. 2015;33:1753-62 pubmed publisher
Fernández J, Rodríguez D, Valenzuela M, Calderon C, Urzúa U, Munroe D, et al. Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription. Mol Cancer. 2014;13:209 pubmed publisher
Lee E, Fertig E, Jin K, Sukumar S, Pandey N, Popel A. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nat Commun. 2014;5:4715 pubmed publisher
Aderhold C, Grobschmidt G, Sauter A, Faber A, Hormann K, Schultz J. Interleukin 4, interleukin 6 and osteopontin-serological markers of head and neck malignancy in primary diagnostics: A pilot study. Oncol Lett. 2014;8:1112-1118 pubmed
Raimondi L, Amodio N, Di Martino M, Altomare E, Leotta M, Caracciolo D, et al. Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: in vitro and in vivo anti-tumor activity. Oncotarget. 2014;5:3039-54 pubmed
Etulain J, Negrotto S, Tribulatti M, Croci D, Carabelli J, Campetella O, et al. Control of angiogenesis by galectins involves the release of platelet-derived proangiogenic factors. PLoS ONE. 2014;9:e96402 pubmed publisher
He S, Wu Q, Gong C, Luo S, Zhang S, Li M, et al. Enhanced efficacy of combination therapy with adeno?associated virus-delivered pigment epithelium-derived factor and cisplatin in a mouse model of Lewis lung carcinoma. Mol Med Rep. 2014;9:2069-76 pubmed publisher
Smith A, Bowers S, Stratman A, Davis G. Hematopoietic stem cell cytokines and fibroblast growth factor-2 stimulate human endothelial cell-pericyte tube co-assembly in 3D fibrin matrices under serum-free defined conditions. PLoS ONE. 2013;8:e85147 pubmed publisher
Townsend K, Spowart J, Huwait H, Eshragh S, West N, Elrick M, et al. Markers of T cell infiltration and function associate with favorable outcome in vascularized high-grade serous ovarian carcinoma. PLoS ONE. 2013;8:e82406 pubmed publisher
Ma X, Hibbert B, McNulty M, Hu T, Zhao X, Ramirez F, et al. Heat shock protein 27 attenuates neointima formation and accelerates reendothelialization after arterial injury and stent implantation: importance of vascular endothelial growth factor up-regulation. FASEB J. 2014;28:594-602 pubmed publisher
Tan J, Prosser H, Vanags L, Monger S, Ng M, Bursill C. High-density lipoproteins augment hypoxia-induced angiogenesis via regulation of post-translational modulation of hypoxia-inducible factor 1?. FASEB J. 2014;28:206-17 pubmed publisher
Perez Lozano M, Sandoval P, Rynne Vidal A, Aguilera A, Jiménez Heffernan J, Albar Vizcaino P, et al. Functional relevance of the switch of VEGF receptors/co-receptors during peritoneal dialysis-induced mesothelial to mesenchymal transition. PLoS ONE. 2013;8:e60776 pubmed publisher
Taylor R, Kashima T, Knowles H, Athanasou N. VEGF, FLT3 ligand, PlGF and HGF can substitute for M-CSF to induce human osteoclast formation: implications for giant cell tumour pathobiology. Lab Invest. 2012;92:1398-406 pubmed publisher
Erdag B, Balcioglu B, Bahadir A, Serhatlı M, Kaçar O, Bahar A, et al. Identification of novel neutralizing single-chain antibodies against vascular endothelial growth factor receptor 2. Biotechnol Appl Biochem. 2011;58:412-22 pubmed publisher
Ikeda N, Murata S, Maruyama T, Tamura T, Nozaki R, Kawasaki T, et al. Platelet-derived adenosine 5'-triphosphate suppresses activation of human hepatic stellate cell: In vitro study. Hepatol Res. 2012;42:91-102 pubmed publisher
Marchbank T, Mahmood A, Harten S, Maxwell P, Playford R. Dimethyloxalyglycine stimulates the early stages of gastrointestinal repair processes through VEGF-dependent mechanisms. Lab Invest. 2011;91:1684-94 pubmed publisher
Liu D, Martin V, Fueyo J, Lee O, Xu J, Cortes Santiago N, et al. Tie2/TEK modulates the interaction of glioma and brain tumor stem cells with endothelial cells and promotes an invasive phenotype. Oncotarget. 2010;1:700-9 pubmed
Merdzhanova G, Gout S, Keramidas M, Edmond V, Coll J, Brambilla C, et al. The transcription factor E2F1 and the SR protein SC35 control the ratio of pro-angiogenic versus antiangiogenic isoforms of vascular endothelial growth factor-A to inhibit neovascularization in vivo. Oncogene. 2010;29:5392-403 pubmed publisher
Chen M, Tzeng C, Chen P, Lin J, Lin T, Chen W, et al. VEGF -460T ? C polymorphism and its association with VEGF expression and outcome to FOLFOX-4 treatment in patients with colorectal carcinoma. Pharmacogenomics J. 2011;11:227-36 pubmed publisher
Hua J, Spee C, Kase S, Rennel E, Magnussen A, Qiu Y, et al. Recombinant human VEGF165b inhibits experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2010;51:4282-8 pubmed publisher
Varet J, Douglas S, Gilmartin L, Medford A, Bates D, Harper S, et al. VEGF in the lung: a role for novel isoforms. Am J Physiol Lung Cell Mol Physiol. 2010;298:L768-74 pubmed publisher
Hashizume H, Falcon B, Kuroda T, Baluk P, Coxon A, Yu D, et al. Complementary actions of inhibitors of angiopoietin-2 and VEGF on tumor angiogenesis and growth. Cancer Res. 2010;70:2213-23 pubmed publisher
Srivastava R, Unterman T, Shankar S. FOXO transcription factors and VEGF neutralizing antibody enhance antiangiogenic effects of resveratrol. Mol Cell Biochem. 2010;337:201-12 pubmed publisher
Moriya J, Minamino T, Tateno K, Okada S, Uemura A, Shimizu I, et al. Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis. Circ Res. 2010;106:391-8 pubmed publisher
Margaritopoulos G, Antoniou K, Soufla G, Karagiannis K, Proklou A, Lasithiotaki I, et al. Upregulation of stromal cell derived factor-1alpha in collagen vascular diseases-associated interstitial pneumonias (CVDs-IPs). Pulm Pharmacol Ther. 2010;23:115-20 pubmed publisher
van der Loos C, Meijer Jorna L, Broekmans M, Ploegmakers H, Teeling P, de Boer O, et al. Anti-human vascular endothelial growth factor (VEGF) antibody selection for immunohistochemical staining of proliferating blood vessels. J Histochem Cytochem. 2010;58:109-18 pubmed publisher
Choudhury K, Yagle K, Swanson P, Krohn K, Rajendran J. A robust automated measure of average antibody staining in immunohistochemistry images. J Histochem Cytochem. 2010;58:95-107 pubmed publisher
Komuro A, Yashiro M, Iwata C, Morishita Y, Johansson E, Matsumoto Y, et al. Diffuse-type gastric carcinoma: progression, angiogenesis, and transforming growth factor beta signaling. J Natl Cancer Inst. 2009;101:592-604 pubmed publisher
Zhu W, Ou Y, Li Y, Xiao R, Shu M, Zhou Y, et al. A small-molecule triptolide suppresses angiogenesis and invasion of human anaplastic thyroid carcinoma cells via down-regulation of the nuclear factor-kappa B pathway. Mol Pharmacol. 2009;75:812-9 pubmed publisher
Gonzalez R, Seurynck Servoss S, Crowley S, Brown M, Omenn G, Hayes D, et al. Development and validation of sandwich ELISA microarrays with minimal assay interference. J Proteome Res. 2008;7:2406-14 pubmed publisher
Allerstorfer S, Sonvilla G, Fischer H, Spiegl Kreinecker S, Gauglhofer C, Setinek U, et al. FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities. Oncogene. 2008;27:4180-90 pubmed publisher
Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, et al. Ultrasensitive flow-based immunoassays using single-molecule counting. Clin Chem. 2007;53:1990-5 pubmed
Ball S, Shuttleworth C, Kielty C. Vascular endothelial growth factor can signal through platelet-derived growth factor receptors. J Cell Biol. 2007;177:489-500 pubmed
Cianfarani F, Zambruno G, Brogelli L, Sera F, Lacal P, Pesce M, et al. Placenta growth factor in diabetic wound healing: altered expression and therapeutic potential. Am J Pathol. 2006;169:1167-82 pubmed
Lucerna M, Zernecke A, de Nooijer R, de Jager S, Bot I, van der Lans C, et al. Vascular endothelial growth factor-A induces plaque expansion in ApoE knock-out mice by promoting de novo leukocyte recruitment. Blood. 2007;109:122-9 pubmed
Hatfield K, Ryningen A, Corbascio M, Bruserud O. Microvascular endothelial cells increase proliferation and inhibit apoptosis of native human acute myelogenous leukemia blasts. Int J Cancer. 2006;119:2313-21 pubmed
Rofstad E, Mathiesen B, Kindem K, Galappathi K. Acidic extracellular pH promotes experimental metastasis of human melanoma cells in athymic nude mice. Cancer Res. 2006;66:6699-707 pubmed
Feltis B, Wignarajah D, Zheng L, Ward C, Reid D, Harding R, et al. Increased vascular endothelial growth factor and receptors: relationship to angiogenesis in asthma. Am J Respir Crit Care Med. 2006;173:1201-7 pubmed
Bates D, MacMillan P, Manjaly J, Qiu Y, Hudson S, Bevan H, et al. The endogenous anti-angiogenic family of splice variants of VEGF, VEGFxxxb, are down-regulated in pre-eclamptic placentae at term. Clin Sci (Lond). 2006;110:575-85 pubmed
Numasaki M, Watanabe M, Suzuki T, Takahashi H, Nakamura A, McAllister F, et al. IL-17 enhances the net angiogenic activity and in vivo growth of human non-small cell lung cancer in SCID mice through promoting CXCR-2-dependent angiogenesis. J Immunol. 2005;175:6177-89 pubmed
Rodriguez Porcel M, Zhu X, Chade A, Amores Arriaga B, Caplice N, Ritman E, et al. Functional and structural remodeling of the myocardial microvasculature in early experimental hypertension. Am J Physiol Heart Circ Physiol. 2006;290:H978-84 pubmed
Li L, Lin X, Staver M, Shoemaker A, Semizarov D, Fesik S, et al. Evaluating hypoxia-inducible factor-1alpha as a cancer therapeutic target via inducible RNA interference in vivo. Cancer Res. 2005;65:7249-58 pubmed
Shikada Y, Yonemitsu Y, Koga T, Onimaru M, Nakano T, Okano S, et al. Platelet-derived growth factor-AA is an essential and autocrine regulator of vascular endothelial growth factor expression in non-small cell lung carcinomas. Cancer Res. 2005;65:7241-8 pubmed
Tamaki M, Saito R, Ogawa O, Yoshimura N, Ueda T. Possible mechanisms inducing glomerulations in interstitial cystitis: relationship between endoscopic findings and expression of angiogenic growth factors. J Urol. 2004;172:945-8 pubmed
Caine G, Blann A, Stonelake P, Ryan P, Lip G. Plasma angiopoietin-1, angiopoietin-2 and Tie-2 in breast and prostate cancer: a comparison with VEGF and Flt-1. Eur J Clin Invest. 2003;33:883-90 pubmed
Barbour A, Reeder J, Walsh M, Fawcett J, Antalis T, Gotley D. Expression of the CD44v2-10 isoform confers a metastatic phenotype: importance of the heparan sulfate attachment site CD44v3. Cancer Res. 2003;63:887-92 pubmed
Zhou Y, McMaster M, Woo K, Janatpour M, Perry J, Karpanen T, et al. Vascular endothelial growth factor ligands and receptors that regulate human cytotrophoblast survival are dysregulated in severe preeclampsia and hemolysis, elevated liver enzymes, and low platelets syndrome. Am J Pathol. 2002;160:1405-23 pubmed
Takayama K, Suzuki J, Kawauchi M, Tsukioka K, Wada Y, Zhang T, et al. Hepatocyte growth factor and vascular endothelial growth factor expression in pig-to-primate xenotransplanted hearts. Transplant Proc. 2000;32:987-9 pubmed
product information
master code :
MAB293
SKU :
MAB293-100
product name :
Human/Primate VEGF Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human/Primate VEGF Antibody from R&D Systems is a mouse monoclonal antibody to VEGF. This antibody reacts with bovine,complex species category,human,mouse,porcine,primate,primate - macaca mulatta (rhesus macaque),rat. The Human/Primate VEGF Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,ELISA Detection,Bioassay,Array Development,ELISA Development,ELISA Microarray Development,Flow Cytometry,Cell Culture,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).
target :
VEGF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
26503
conjugate :
Unconjugated
host :
Mouse
isotype :
IgG2b
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Bovine,Complex Species Category,Human,Mouse,Porcine,Primate,Primate - Macaca mulatta (Rhesus Macaque),Rat
specificity :
Detects human VEGF165 and human VEGF121 in ELISAs and Western blots. In ELISAs, approximately 10% cross-reactivity with recombinant mouse (rm) VEGF and recombinant rat (rr)VEGF and no cross-reactivity with recombinant human (rh) VEGF-D is observed.
gene symbol :
VEGFA
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Detection of Recombinant Human VEGF antibody by Western Blot.
accessionNumbers :
NP_001165097.1
applications :
ELISA Detection,Neutralization,Western Blot,Bioassay,Array Development,ELISA Development,ELISA Microarray Development,Flow Cytometry,Cell Culture,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,ELISA Capture (Matched Antibody Pair)
USD :
509 USD
alt names :
MVCD1, VAS, vascular endothelial growth factor A, Vascular permeability factor, Vasculotropin, VEGFA, VEGF-A, VEGFMGC70609, VPF, VPFvascular endothelial growth factor
storage :
Store the unopened product at -20 to -70 ░C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.