Human/Mouse BMP-10 Antibody | R&D Systems MAB2926 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse BMP-10 Antibody

catalog :

MAB2926

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

462732

reactivity :

human, mouse

application :

western blot, immunohistochemistry, neutralization, blocking or activating experiments

citations: 9

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; fig 6 western blot; mouse; fig 2b	Jumabay M, Zhumabai J, Mansurov N, Niklason K, Guihard P, Cubberly M, et al. Combined effects of bone morphogenetic protein 10 and crossveinless-2 on cardiomyocyte differentiation in mouse adipocyte-derived stem cells. J Cell Physiol. 2018;233:1812-1822 pubmed publisher
blocking or activating experiments; mouse; fig 5c	Ruiz S, Chandakkar P, Zhao H, Papoin J, Chatterjee P, Christen E, et al. Tacrolimus rescues the signaling and gene expression signature of endothelial ALK1 loss-of-function and improves HHT vascular pathology. Hum Mol Genet. 2017;26:4786-4798 pubmed publisher
western blot; human; loading ...; fig 6b	Jiang H, Salmon R, Upton P, Wei Z, Lawera A, Davenport A, et al. The Prodomain-bound Form of Bone Morphogenetic Protein 10 Is Biologically Active on Endothelial Cells. J Biol Chem. 2016;291:2954-66 pubmed publisher
	Owen N, Alexander G, Sen S, Bunclark K, Polwarth G, Pepke Zaba J, et al. Reduced circulating BMP10 and BMP9 and elevated endoglin are associated with disease severity, decompensation and pulmonary vascular syndromes in patients with cirrhosis. EBioMedicine. 2020;56:102794 pubmed publisher
	Tillet E, Ouarné M, Desroches Castan A, Mallet C, Subileau M, Didier R, et al. A heterodimer formed by bone morphogenetic protein 9 (BMP9) and BMP10 provides most BMP biological activity in plasma. J Biol Chem. 2018;293:10963-10974 pubmed publisher
	Ruiz S, Zhao H, Chandakkar P, Chatterjee P, Papoin J, Blanc L, et al. A mouse model of hereditary hemorrhagic telangiectasia generated by transmammary-delivered immunoblocking of BMP9 and BMP10. Sci Rep. 2016;5:37366 pubmed publisher
	Levet S, OuarnÃ© M, Ciais D, Coutton C, Subileau M, Mallet C, et al. BMP9 and BMP10 are necessary for proper closure of the ductus arteriosus. Proc Natl Acad Sci U S A. 2015;112:E3207-15 pubmed publisher
	Ricard N, Ciais D, Levet S, Subileau M, Mallet C, Zimmers T, et al. BMP9 and BMP10 are critical for postnatal retinal vascular remodeling. Blood. 2012;119:6162-71 pubmed publisher
	Kahr P, Piccini I, Fabritz L, Greber B, SchÃ¶ler H, Scheld H, et al. Systematic analysis of gene expression differences between left and right atria in different mouse strains and in human atrial tissue. PLoS ONE. 2011;6:e26389 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB2926

SKU :

MAB2926-100

product name :

Human/Mouse BMP-10 Antibody

description :

The Human/Mouse BMP-10 Antibody from R&D Systems is a mouse monoclonal antibody to BMP-10. This antibody reacts with human, mouse. The Human/Mouse BMP-10 Antibody has been validated for the following applications: Western Blot, Neutralization.

target :

BMP-10

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

462732

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human BMP-10, Asn317-Arg424, Accession # O95393

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human, Mouse

specificity :

Detects human BMP-10 in direct ELISAs and Western blots. In Western blots, no cross-reactivity with recombinant human (rh) BMP-1.1, 2, 3, 3b, 4, 5, 6, 7, 9, 15, or the pro region of rhBMP-10 is observed. In direct ELISAs, approximately 90% cross-reactivity with recombinant mouse BMP-10 is observed.

gene symbol :

BMP10

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB2926

accessionNumbers :

O95393

applications :

Western Blot, Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

BMP10, BMP-10, bone morphogenetic protein 10, MGC126783

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.