Human IGF-II/IGF2 Antibody | R&D Systems MAB292 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IGF-II/IGF2 Antibody

catalog :

MAB292

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

75015

reactivity :

human

application :

neutralization

citations: 4

Reference
De Giovanni C, Nanni P, Landuzzi L, Ianzano M, Nicoletti G, Croci S, et al. Immune targeting of autocrine IGF2 hampers rhabdomyosarcoma growth and metastasis. BMC Cancer. 2019;19:126 pubmed publisher
Guan S, Lam A, Newman J, Chua K, Kok C, Chong S, et al. Matrix metalloproteinase-1 facilitates MSC migration via cleavage of IGF-2/IGFBP2 complex. FEBS Open Bio. 2018;8:15-26 pubmed publisher
Mancini M, Gariboldi M, Taiana E, Bonzi M, Craparotta I, Pagin M, et al. Co-targeting the IGF system and HIF-1 inhibits migration and invasion by (triple-negative) breast cancer cells. Br J Cancer. 2014;110:2865-73 pubmed publisher
Adkins R, Fain J, Krushkal J, Klauser C, Magann E, Morrison J. Association between paternally inherited haplotypes upstream of the insulin gene and umbilical cord IGF-II levels. Pediatr Res. 2007;62:451-5 pubmed

product information

brand :

R&D Systems

master code :

MAB292

SKU :

MAB292-100

product name :

Human IGF-II/IGF2 Antibody

description :

The Human IGF-II/IGF2 Antibody from R&D Systems is a mouse monoclonal antibody to IGF-II/IGF2. This antibody reacts with human. The Human IGF-II/IGF2 Antibody has been validated for the following applications: Neutralization.

target :

IGF-II/IGF2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

75015

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IGF-II/IGF2, Ala25-Glu91, Accession # P01344.1

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human IGF-II/IGF2 in direct ELISA and Western blots. This antibody shows 100% cross-reactivity with recombinant mouse (rm) IGF-II and no cross-reactivity with recombinant human IGF-I or rmIGF-I.

gene symbol :

IGF2

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB292

accessionNumbers :

P01344.1

applications :

Neutralization

2020 USD :

339

2021 USD :

359 USD

alt names :

C11orf43, chromosome 11 open reading frame 43, FLJ22066, FLJ44734, GRDF, IGF2, IGF-2, IGFII, IGF-II, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor II, insulin-like growth factor type 2, MSA, PEG2, PP9974, somatomedin-A

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.