product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human Granzyme B Antibody
catalog :
MAB2906
quantity :
100 ug (also 25 ug)
price :
449 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
351927
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
more info or order :
citations: 4
Reference
Jamann H, Cui Q, Desu H, Pernin F, Tastet O, Halaweh A, et al. Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes. Front Immunol. 2022;13:850616 pubmed publisher
Jacob F, Salinas R, Zhang D, Nguyen P, Schnoll J, Wong S, et al. A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. Cell. 2020;180:188-204.e22 pubmed publisher
Zhang M, Chen L, Li Y, Kong D. PD‑L1/PD‑1 axis serves an important role in natural killer cell‑induced cytotoxicity in osteosarcoma. Oncol Rep. 2019;42:2049-2056 pubmed publisher
Paidipally P, Tripathi D, Van A, Radhakrishnan R, Dhiman R, Venkatasubramanian S, et al. Interleukin-21 Regulates Natural Killer Cell Responses During Mycobacterium tuberculosis Infection. J Infect Dis. 2018;217:1323-1333 pubmed publisher
product information
master code :
MAB2906
SKU :
MAB2906
product name :
Human Granzyme B Antibody
unit size :
100 ug (also 25 ug)
description :
The Human Granzyme B Antibody from R&D Systems is a mouse monoclonal antibody to Granzyme B. This antibody reacts with human. The Human Granzyme B Antibody has been validated for the following applications: Immunocytochemistry,Immunohistochemistry,Western Blot,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
Granzyme B
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
351927
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human Granzyme B, Gly19-Tyr247, Accession # P10144
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human Granzyme B in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) Granzyme A, rhGranzyme H, recombinant mouse (rm) Granzyme B, rmGranzyme C, rmGranzyme D, or rmGranzyme G.
gene symbol :
GZMB
top caption :
Detection of Human Granzyme B antibody by Western Blot.
accessionNumbers :
P10144
applications :
Immunocytochemistry,Immunohistochemistry,Western Blot,Simple Western,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
449 USD
alt names :
C11, CCPI, CGL1, CGL-1, CSPB, CSP-B, CTLA1, CTLA-1, CTSGL1, Fragmentin-2, granzyme B, Granzyme-2, GranzymeB, GRB, GrzB, GZMB, HLP, SECT
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.