product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human/Rat SOX10 Antibody
catalog :
MAB2864
quantity :
100 ug (also 25 ug)
price :
509 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
20B7
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation
more info or order :
R&D Systems product webpage
citations: 22
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; mouse; 1:100; fig 5g
Di Luca M, Fitzpatrick E, Burtenshaw D, Liu W, Helt J, Hakimjavadi R, et al. The calcium binding protein S100β marks hedgehog-responsive resident vascular stem cells within vascular lesions. NPJ Regen Med. 2021;6:10 pubmed publisher
Guillemot Legris O, Girmahun G, Shipley R, Phillips J. Local Administration of Minocycline Improves Nerve Regeneration in Two Rat Nerve Injury Models. Int J Mol Sci. 2023;24: pubmed publisher
Ye D, Qu S, Yang Y, Wang Z, Wang Q, Liu W, et al. Intrauterine desensitization enables long term survival of human oligodendrocyte progenitor cells without immunosuppression. iScience. 2023;26:106647 pubmed publisher
Ye D, Wang Q, Yang Y, Chen B, Zhang F, Wang Z, et al. Identifying Genes that Affect Differentiation of Human Neural Stem Cells and Myelination of Mature Oligodendrocytes. Cell Mol Neurobiol. 2023;43:2337-2358 pubmed publisher
Reschke R, Yu J, Flood B, Higgs E, Hatogai K, Gajewski T. Immune cell and tumor cell-derived CXCL10 is indicative of immunotherapy response in metastatic melanoma. J Immunother Cancer. 2021;9: pubmed publisher
Laberthonnière C, Novoa Del Toro E, Chevalier R, Broucqsault N, Rao V, Trani J, et al. AKT Signaling Modifies the Balance between Cell Proliferation and Migration in Neural Crest Cells from Patients Affected with Bosma Arhinia and Microphthalmia Syndrome. Biomedicines. 2021;9: pubmed publisher
Fu A, Lui K, Tang C, Ng R, Lai F, Lau S, et al. Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease. Genome Res. 2020;30:1618-1632 pubmed publisher
Ching R, Wiberg M, Kingham P. Schwann cell-like differentiated adipose stem cells promote neurite outgrowth via secreted exosomes and RNA transfer. Stem Cell Res Ther. 2018;9:266 pubmed publisher
Ly P, Stewart C, Pallen C. PTP? is required for laminin-2-induced Fyn-Akt signaling to drive oligodendrocyte differentiation. J Cell Sci. 2018;131: pubmed publisher
Janardhan K, Jensen H, Clayton N, Herbert R. Immunohistochemistry in Investigative and Toxicologic Pathology. Toxicol Pathol. 2018;46:488-510 pubmed publisher
Cronin J, Loftus S, Baxter L, Swatkoski S, Gucek M, Pavan W. Identification and functional analysis of SOX10 phosphorylation sites in melanoma. PLoS ONE. 2018;13:e0190834 pubmed publisher
Toyoshima M, Akamatsu W, Okada Y, Ohnishi T, Balan S, Hisano Y, et al. Analysis of induced pluripotent stem cells carrying 22q11.2 deletion. Transl Psychiatry. 2016;6:e934 pubmed publisher
Lankford L, Selby T, Becker J, Ryzhuk V, Long C, Farmer D, et al. Early gestation chorionic villi-derived stromal cells for fetal tissue engineering. World J Stem Cells. 2015;7:195-207 pubmed publisher
Göttle P, Sabo J, Heinen A, Venables G, Torres K, Tzekova N, et al. Oligodendroglial maturation is dependent on intracellular protein shuttling. J Neurosci. 2015;35:906-19 pubmed publisher
Coquenlorge S, Duchalais E, Chevalier J, Cossais F, Rolli Derkinderen M, Neunlist M. Modulation of lipopolysaccharide-induced neuronal response by activation of the enteric nervous system. J Neuroinflammation. 2014;11:202 pubmed publisher
Xu W, Sun Y, Zhang J, Xu K, Pan L, He L, et al. Perivascular-derived stem cells with neural crest characteristics are involved in tendon repair. Stem Cells Dev. 2015;24:857-68 pubmed publisher
Jacob C, Lötscher P, Engler S, Baggiolini A, Varum Tavares S, Brügger V, et al. HDAC1 and HDAC2 control the specification of neural crest cells into peripheral glia. J Neurosci. 2014;34:6112-22 pubmed publisher
Cronin J, Watkins Chow D, Incao A, Hasskamp J, Schönewolf N, Aoude L, et al. SOX10 ablation arrests cell cycle, induces senescence, and suppresses melanomagenesis. Cancer Res. 2013;73:5709-18 pubmed publisher
Gordon J, Sariyer I, de la Fuente Granada M, Augelli B, Otte J, Azizi S, et al. Neural Crest Cells Isolated from the Bone Marrow of Transgenic Mice Express JCV T-Antigen. PLoS ONE. 2013;8:e65947 pubmed publisher
Jacob C, Christen C, Pereira J, Somandin C, Baggiolini A, Lötscher P, et al. HDAC1 and HDAC2 control the transcriptional program of myelination and the survival of Schwann cells. Nat Neurosci. 2011;14:429-36 pubmed publisher
Hunt D, Sajic M, Phillips H, Henderson D, Compston A, Smith K, et al. Origins of gliogenic stem cell populations within adult skin and bone marrow. Stem Cells Dev. 2010;19:1055-65 pubmed publisher
Hunt D, Morris P, Sterling J, Anderson J, Joannides A, Jahoda C, et al. A highly enriched niche of precursor cells with neuronal and glial potential within the hair follicle dermal papilla of adult skin. Stem Cells. 2008;26:163-72 pubmed
product information
master code :
MAB2864
SKU :
MAB2864
product name :
Human/Rat SOX10 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human/Rat SOX10 Antibody from R&D Systems is a mouse monoclonal antibody to SOX10. This antibody reacts with human,mouse,rat. The Human/Rat SOX10 Antibody has been validated for the following applications: Immunohistochemistry,Immunoprecipitation,Western Blot,Immunocytochemistry.
target :
SOX10
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
20B7
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant rat SOX10, aa 1-118
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse,Rat
specificity :
Detects human and rat SOX10. Epitope-mapping experiments indicated that clone 20B7 recognizes a determinant in the first 65 amino acids, which contains sequences unique to SOX10 (1).
gene symbol :
SOX10
top caption :
SOX10 antibody in BG01V Human Embryonic Stem Cells by Immunocytochemistry (ICC).
applications :
Immunohistochemistry,Immunoprecipitation,Western Blot,Immunocytochemistry
USD :
509 USD
alt names :
DOM, MGC15649, PCWH, SRY (sex determining region Y)-box 10, SRY-related HMG-box gene 10, transcription factor SOX-10, WS4, WS4C, WS4mouse, human homolog of
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.