Human IFN-gamma Antibody | R&D Systems MAB285 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IFN-gamma Antibody

catalog :

MAB285

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25718

reactivity :

human

application :

immunocytochemistry, neutralization, blocking or activating experiments

citations: 20

Published Application/Species/Sample/Dilution	Reference
blocking or activating experiments; human; loading ...; fig 3	Schiavano G, Dominici S, Rinaldi L, Cangiano A, Brandi G, Magnani M. Modulation of Stat-1 in Human Macrophages Infected with Different Species of Intracellular Pathogenic Bacteria. J Immunol Res. 2016;2016:5086928 pubmed publisher
	Szabo P, Levitin H, Miron M, Snyder M, Senda T, Yuan J, et al. Single-cell transcriptomics of human T cells reveals tissue and activation signatures in health and disease. Nat Commun. 2019;10:4706 pubmed publisher
	Zhang F, Liu G, Li D, Wei C, Hao J. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway. J Immunol. 2018;200:1618-1626 pubmed publisher
	Liu Y, Qu L, Liu Y, Roizman B, Zhou G. PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. Proc Natl Acad Sci U S A. 2017;114:E6902-E6911 pubmed publisher
	Longhi M, Vuerich M, Kalbasi A, Kenison J, Yeste A, Csizmadia E, et al. Bilirubin suppresses Th17 immunity in colitis by upregulating CD39. JCI Insight. 2017;2: pubmed publisher
	Paquin Proulx D, Gibbs A, Bachle S, Checa A, Introini A, Leeansyah E, et al. Innate Invariant NKT Cell Recognition of HIV-1-Infected Dendritic Cells Is an Early Detection Mechanism Targeted by Viral Immune Evasion. J Immunol. 2016;197:1843-51 pubmed publisher
	Arterbery A, Osafo Addo A, Avitzur Y, Ciarleglio M, Deng Y, Lobritto S, et al. Production of Proinflammatory Cytokines by Monocytes in Liver-Transplanted Recipients with De Novo Autoimmune Hepatitis Is Enhanced and Induces TH1-like Regulatory T Cells. J Immunol. 2016;196:4040-51 pubmed publisher
	Ranzani V, Rossetti G, Panzeri I, Arrigoni A, Bonnal R, Curti S, et al. The long intergenic noncoding RNA landscape of human lymphocytes highlights the regulation of T cell differentiation by linc-MAF-4. Nat Immunol. 2015;16:318-325 pubmed publisher
	Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE. 2014;9:e96695 pubmed publisher
	Chang H, Sehra S, Goswami R, Yao W, Yu Q, Stritesky G, et al. The transcription factor PU.1 is required for the development of IL-9-producing T cells and allergic inflammation. Nat Immunol. 2010;11:527-34 pubmed publisher
	Chang H, Han L, Goswami R, Nguyen E, Pelloso D, Robertson M, et al. Impaired development of human Th1 cells in patients with deficient expression of STAT4. Blood. 2009;113:5887-90 pubmed publisher
	Seshasayee D, Lee W, Zhou M, Shu J, Suto E, Zhang J, et al. In vivo blockade of OX40 ligand inhibits thymic stromal lymphopoietin driven atopic inflammation. J Clin Invest. 2007;117:3868-78 pubmed
	Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos G, et al. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia. Exp Hematol. 2006;34:1312-22 pubmed
	Ebert E, Mehta V. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription. Cell Immunol. 2006;241:7-13 pubmed
	Methe H, Wiegand D, Welsch U, Krombach F, Meiser B, Nabauer M, et al. Peripheral expansion of circulating T-helper 1 cells predicts coronary endothelial dysfunction after cardiac transplantation. J Heart Lung Transplant. 2005;24:833-40 pubmed
	Miranda Carús M, Balsa A, Benito Miguel M, Pérez de Ayala C, Martin Mola E. IL-15 and the initiation of cell contact-dependent synovial fibroblast-T lymphocyte cross-talk in rheumatoid arthritis: effect of methotrexate. J Immunol. 2004;173:1463-76 pubmed
	Herrero C, Hu X, Li W, Samuels S, Sharif M, Kotenko S, et al. Reprogramming of IL-10 activity and signaling by IFN-gamma. J Immunol. 2003;171:5034-41 pubmed
	Durali D, de Goër de Herve M, Giron Michel J, Azzarone B, Delfraissy J, Taoufik Y. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment. Blood. 2003;102:4084-9 pubmed
	Wolk K, Kunz S, Asadullah K, Sabat R. Cutting edge: immune cells as sources and targets of the IL-10 family members?. J Immunol. 2002;168:5397-402 pubmed
	Ong P, Hamid Q, Travers J, Strickland I, Al Kerithy M, Boguniewicz M, et al. Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. J Immunol. 2002;168:505-10 pubmed

product information

brand :

R&D Systems

master code :

MAB285

SKU :

MAB285-100

product name :

Human IFN-gamma Antibody

description :

The Human IFN-gamma Antibody from R&D Systems is a mouse monoclonal antibody to IFN-gamma. This antibody reacts with human. The Human IFN-gamma Antibody has been validated for the following applications: Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry.

target :

IFN-gamma

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

25718

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human IFN-gamma , Gln24-Gln166, Accession # AAP20098.1

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IFN-gamma .

gene symbol :

IFNG

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB285

accessionNumbers :

AAP20098.1

applications :

Neutralization, Intracellular Staining by Flow Cytometry, Immunocytochemistry

2020 USD :

339

2021 USD :

369 USD

alt names :

IFG, IFI, IFNG, IFNgamma, IFN-gamma, Immune interferon, interferon gamma, interferon, gamma

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.