Human Common gamma Chain/IL-2 R gamma Antibody | R&D Systems MAB2842 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human Common gamma Chain/IL-2 R gamma Antibody

catalog :

MAB2842

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

633162

reactivity :

human

application :

neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 5

Reference
Wu W, Shiu C, Tong T, LEUNG S, Hui C. Suppression of NK Cell Activation by JAK3 Inhibition: Implication in the Treatment of Autoimmune Diseases. J Immunol Res. 2023;2023:8924603 pubmed publisher
Devocelle A, Lecru L, Francois H, Desterke C, Gallerne C, Eid P, et al. Inhibition of TGF-β1 Signaling by IL-15: A Novel Role for IL-15 in the Control of Renal Epithelial-Mesenchymal Transition: IL-15 Counteracts TGF-β1-Induced EMT in Renal Fibrosis. Int J Cell Biol. 2019;2019:9151394 pubmed publisher
Jiang J, Chen X, An H, Yang B, Zhang F, Cheng X. Enhanced immune response of MAIT cells in tuberculous pleural effusions depends on cytokine signaling. Sci Rep. 2016;6:32320 pubmed publisher
Mujib S, Jones R, Lo C, Aidarus N, Clayton K, Sakhdari A, et al. Antigen-independent induction of Tim-3 expression on human T cells by the common ?-chain cytokines IL-2, IL-7, IL-15, and IL-21 is associated with proliferation and is dependent on the phosphoinositide 3-kinase pathway. J Immunol. 2012;188:3745-56 pubmed publisher
Giron Michel J, Azzi S, Khawam K, Mortier E, Caignard A, Devocelle A, et al. Interleukin-15 plays a central role in human kidney physiology and cancer through the ?c signaling pathway. PLoS ONE. 2012;7:e31624 pubmed publisher

product information

master code :

MAB2842

SKU :

MAB2842

product name :

Human Common gamma Chain/IL-2 R gamma Antibody

unit size :

100 ug (also 25 ug)

description :

The Human Common gamma Chain/IL-2 R gamma Antibody from R&D Systems is a mouse monoclonal antibody to Common gamma Chain/IL-2 R gamma. This antibody reacts with human. The Human Common gamma Chain/IL-2 R gamma Antibody has been validated for the following applications: Immunocytochemistry,Flow Cytometry,Neutralization,CyTOF-ready.

target :

Common gamma Chain/IL-2 R gamma

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

633162

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf21- derived recombinant human Common gamma Chain/IL-2 gamma , Leu23-Asn254, Accession # P31785

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Common gamma Chain/IL-2 R gamma in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2 R alpha , rhIL-2 R▀, rhIL-15 R alpha , recombinant mouse IL-2 R gamma , or recombinant canine IL-2 R alpha is observed. In Western blots, approximately 80% cross-reactivity with recombinant human IL-2 R▀, 50% cross-reactivity with rhIL-15 R alpha and recombinant mouse IL-2 R alpha , and no cross-reactivity with rhIL-2 R alpha is observed.

gene symbol :

IL2RG

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Detection of Common ? Chain/IL-2 R? antibody in Human PBMC antibody by Flow Cytometry.

accessionNumbers :

P31785

applications :

Flow Cytometry,Neutralization,CyTOF-ready

USD :

469 USD

alt names :

CD132, CD132 antigen, CIDX, combined immunodeficiency, X-linked, common cytokine receptor gamma chain, common gamma-chain, cytokine receptor common subunit gamma, gamma(c), IL-2 R gamma, IL-2 receptor subunit gamma, IL2R gamma, IL-2R subunit gamma, IL2RG, IL-2RG, IMD4, interleukin 2 receptor, gamma, Interleukin-2 receptor subunit gamma, p64, SCIDX, SCIDX1, severe combined immunodeficiency

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage