Human CCL8/MCP-2 Antibody | R&D Systems MAB281-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CCL8/MCP-2 Antibody

catalog :

MAB281-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

35509

reactivity :

human

application :

ELISA, immunocytochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 6

Reference
Parween F, Singh S, Zhang H, Kathuria N, Otaizo Carrasquero F, Shamsaddini A, et al. Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cells. bioRxiv. 2023;: pubmed publisher
Manning L, Cutts J, Stanisic D, Laman M, Carmagnac A, Allen S, et al. A Toll-like receptor-1 variant and its characteristic cellular phenotype is associated with severe malaria in Papua New Guinean children. Genes Immun. 2016;17:52-9 pubmed publisher
Karta M, Wickert L, Curran C, Gavala M, Denlinger L, Gern J, et al. Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages. J Allergy Clin Immunol. 2014;133:1227-1230.e4 pubmed publisher
Struyf S, Proost P, Vandercappellen J, Dempe S, Noyens B, Nelissen S, et al. Synergistic up-regulation of MCP-2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti-tumoral effects. Eur J Immunol. 2009;39:843-57 pubmed publisher
Haringman J, Smeets T, Reinders Blankert P, Tak P. Chemokine and chemokine receptor expression in paired peripheral blood mononuclear cells and synovial tissue of patients with rheumatoid arthritis, osteoarthritis, and reactive arthritis. Ann Rheum Dis. 2006;65:294-300 pubmed
Tay S, McCormack A, Rose M. Effect of cognate human CD4+ T cell and endothelial cell interactions upon chemokine production. Transplantation. 2004;78:987-94 pubmed

product information

master code :

MAB281

SKU :

MAB281-100

product name :

Human CCL8/MCP-2 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CCL8/MCP-2 Antibody from R&D Systems is a mouse monoclonal antibody to CCL8/MCP-2. This antibody reacts with human. The Human CCL8/MCP-2 Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),Immunohistochemistry-Frozen,Immunocytochemistry,Neutralization,ELISA Capture (Matched Antibody Pair).

target :

CCL8/MCP-2

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

35509

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CCL8/MCP-2

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CCL8/MCP-2 in ELISAs. In ELISAs, this antibody shows less than 0.1% cross-reactivity with recombinant human (rh) CCL15 and rmCCL3.

gene symbol :

CCL8

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CCL8/MCP-2 and Neutralization by Human CCL8/MCP-2 Antibody.

applications :

ELISA Development,ELISA Development (Capture),Immunohistochemistry-Frozen,Immunocytochemistry,Neutralization,ELISA Capture (Matched Antibody Pair)

USD :

469 USD

alt names :

C-C motif chemokine 8, chemokine (C-C motif) ligand 8, HC14, MCP2, MCP-2, member 8 (monocyte chemotactic protein 2), monocyte chemoattractant protein 2, SCYA10, small-inducible cytokine A8

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage