product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse CLEC4F/CLECSF13 Antibody
catalog :
MAB2784
quantity :
100 ug (also 25 ug)
price :
479 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
370901
reactivity :
mouse
application :
western blot, immunohistochemistry
more info or order :
R&D Systems product webpage
citations: 12
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:200; loading ...; fig 5b
Kucsera D, T xf3 th V, Gerg x151 D, V xf6 r xf6 s I, On xf3 di Z, G xf6 rbe A, et al. Characterization of the CDAA Diet-Induced Non-alcoholic Steatohepatitis Model: Sex-Specific Differences in Inflammation, Fibrosis, and Cholesterol Metabolism in Middle-Aged Mice. Front Physiol. 2021;12:609465 pubmed publisher
Wang X, Wang Z, Liu B, Jin R, Song Y, Fei R, et al. Characteristic gene expression in the liver monocyte-macrophage-DC system is associated with the progression of fibrosis in NASH. Front Immunol. 2023;14:1098056 pubmed publisher
Vilmundarson R, Heydarikhorneh N, Duong A, Ho T, Keyhanian K, Soheili F, et al. Savior Siblings Might Rescue Fetal Lethality But Not Adult Lymphoma in Irf2bp2-Null Mice. Front Immunol. 2022;13:868053 pubmed publisher
Guilliams M, Bonnardel J, Haest B, Vanderborght B, Wagner C, Remmerie A, et al. Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches. Cell. 2022;185:379-396.e38 pubmed publisher
Jiang Y, Tang Y, Hoover C, Kondo Y, Huang D, Restagno D, et al. Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice. Cell Death Differ. 2021;28:3009-3021 pubmed publisher
Voisin M, Shrestha E, Rollet C, Nikain C, Josefs T, Mahe M, et al. Inhibiting LXRα phosphorylation in hematopoietic cells reduces inflammation and attenuates atherosclerosis and obesity in mice. Commun Biol. 2021;4:420 pubmed publisher
Remmerie A, Martens L, Thoné T, Castoldi A, Seurinck R, Pavie B, et al. Osteopontin Expression Identifies a Subset of Recruited Macrophages Distinct from Kupffer Cells in the Fatty Liver. Immunity. 2020;53:641-657.e14 pubmed publisher
Osinski V, Bauknight D, Dasa S, Harms M, Kroon T, Marshall M, et al. In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects. Theranostics. 2020;10:585-601 pubmed publisher
Bauknight D, Osinski V, Dasa S, Nguyen A, Marshall M, Hartman J, et al. Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects. PLoS ONE. 2019;14:e0224917 pubmed publisher
Kim S, Feng D, Guillot A, Dai S, Liu F, Hwang S, et al. Adipocyte Death Preferentially Induces Liver Injury and Inflammation Through the Activation of Chemokine (C-C Motif) Receptor 2-Positive Macrophages and Lipolysis. Hepatology. 2019;69:1965-1982 pubmed publisher
van der Tuin S, Li Z, Berbée J, Verkouter I, Ringnalda L, Neele A, et al. Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80+Clec4f+Vsig4+Ly6C- Kupffer Cell Subsets. J Am Heart Assoc. 2018;7: pubmed publisher
Itoh M, Suganami T, Kato H, Kanai S, Shirakawa I, Sakai T, et al. CD11c+ resident macrophages drive hepatocyte death-triggered liver fibrosis in a murine model of nonalcoholic steatohepatitis. JCI Insight. 2017;2: pubmed publisher
product information
master code :
MAB2784
SKU :
MAB2784
product name :
Mouse CLEC4F/CLECSF13 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse CLEC4F/CLECSF13 Antibody from R&D Systems is a rat monoclonal antibody to CLEC4F/CLECSF13. This antibody reacts with mouse. The Mouse CLEC4F/CLECSF13 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot.
target :
CLEC4F/CLECSF13
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
370901
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse CLEC4F/CLECSF13, Ala65-Gly548, Accession # P70194
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse CLEC4F/CLECSF13 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) CLECSF4F, rhCLEC4D, rhCLEC4E, recombinant mouse (rm) OCIL, and rmOCIL-rp2 is observed.
gene symbol :
CLEC4F
top caption :
CLEC4F/CLECSF13 antibody in Mouse Liver by Immunohistochemistry (IHC-Fr).
accessionNumbers :
P70194
applications :
Immunohistochemistry,Western Blot
USD :
479 USD
alt names :
CLECSF13, C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 13, C-type lectin 13, C-type lectin domain family 4, member F, Galactose Particle Receptor, KCLR, KCR
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.