Human IL-22 R alpha 1 Antibody | R&D Systems MAB2770 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IL-22 R alpha 1 Antibody

catalog :

MAB2770

quantity :

100 ug (also 25 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

305405

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 11

Reference
Dayton J, Yuan Y, Pacumio L, Dorflinger B, Yoo S, Olson M, et al. Expression of IL-20 Receptor Subunit β Is Linked to EAE Neuropathology and CNS Neuroinflammation. Front Cell Neurosci. 2021;15:683687 pubmed publisher
Chiu Y, Hsing C, Li C, Lee C, Hsu Y, Chang M. Anti-IL-20 monoclonal antibody inhibited tumor growth in hepatocellular carcinoma. Sci Rep. 2017;7:17609 pubmed publisher
Treerat P, Prince O, Cruz Lagunas A, Muñoz Torrico M, Salazar Lezama M, Selman M, et al. Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection. Mucosal Immunol. 2017;10:1069-1081 pubmed publisher
El Zayadi A, Jones E, Churchman S, Baboolal T, Cuthbert R, El Jawhari J, et al. Interleukin-22 drives the proliferation, migration and osteogenic differentiation of mesenchymal stem cells: a novel cytokine that could contribute to new bone formation in spondyloarthropathies. Rheumatology (Oxford). 2017;56:488-493 pubmed publisher
Ma Q, Jin B, Zhang Y, Shi Y, Zhang C, Luo D, et al. Secreted recombinant human IL-24 protein inhibits the proliferation of esophageal squamous cell carcinoma Eca-109 cells in vitro and in vivo. Oncol Rep. 2016;35:2681-90 pubmed publisher
Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, et al. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes. J Neuroinflammation. 2015;12:119 pubmed publisher
Ma Q, Deng X, Jin B, Zhang Y, Luo D, Song H, et al. A novel human interleukin-24 peptide created by computer-guided design contributes to suppression of proliferation in esophageal squamous cell carcinoma Eca-109 cells. Oncol Rep. 2015;33:193-200 pubmed publisher
Lerman G, Sharon M, Leibowitz Amit R, Sidi Y, Avni D. The crosstalk between IL-22 signaling and miR-197 in human keratinocytes. PLoS ONE. 2014;9:e107467 pubmed publisher
Dash R, Bhoopathi P, Das S, Sarkar S, Emdad L, Dasgupta S, et al. Novel mechanism of MDA-7/IL-24 cancer-specific apoptosis through SARI induction. Cancer Res. 2014;74:563-74 pubmed publisher
Zhang F, Shang D, Zhang Y, Tian Y. Interleukin-22 suppresses the growth of A498 renal cell carcinoma cells via regulation of STAT1 pathway. PLoS ONE. 2011;6:e20382 pubmed publisher
Chang Y, Al Alwan L, Risse P, Roussel L, Rousseau S, Halayko A, et al. TH17 cytokines induce human airway smooth muscle cell migration. J Allergy Clin Immunol. 2011;127:1046-53.e1-2 pubmed publisher

product information

master code :

MAB2770

SKU :

MAB2770

product name :

Human IL-22 R alpha 1 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human IL-22 R alpha 1 Antibody from R&D Systems is a mouse monoclonal antibody to IL-22R alpha 1. This antibody reacts with human,mouse. The Human IL-22 R alpha 1 Antibody has been validated for the following applications: Neutralization,Immunocytochemistry,Flow Cytometry,Western Blot,Immunohistochemistry,CyTOF-ready.

target :

IL-22 R alpha 1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

305405

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Chinese hamster ovary cell line CHO-derived recombinant human IL-22 R alpha 1, Pro18-Thr228, Accession # Q8N6P7

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human IL-22 R alpha 1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-10, rhIL-22BP or rhIL-20 R alpha is observed.

gene symbol :

IL22RA1

top caption :

Detection of IL-22 Ra1 antibody in COLO 205 Human Cell Line antibody by Flow Cytometry.

accessionNumbers :

Q8N6P7

applications :

Immunocytochemistry,Flow Cytometry,Western Blot,Neutralization,Immunohistochemistry,CyTOF-ready

USD :

459 USD

alt names :

CRF2-9, CRF2-9interleukin 22 receptor, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL22R, IL22R alpha 1, IL22R1, IL22RA1, IL-22RA1, IL-22R-alpha-1, IL-TIF-R1, interleukin 22 receptor, alpha 1, interleukin-22 receptor subunit alpha-1, zcytoR11

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage