product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MFG-E8 Antibody
catalog :
MAB27671
quantity :
100 ug (also 25 ug)
price :
489 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
278918
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 5
Reference
Sokolova D, Ghansah S, Puletti F, Georgiades T, De Schepper S, Zheng Y, et al. Astrocyte-derived MFG-E8 facilitates microglial synapse elimination in Alzheimer's disease mouse models. bioRxiv. 2024;: pubmed publisher
Chaung W, Zhang F, Ma G, Yen H, Jacob A, Brenner M, et al. Development of human cell-expressed tag-free rhMFG-E8 as a radiation mitigator and a therapeutic for acute kidney injury. Res Sq. 2023;: pubmed publisher
Park C, Kehrl J. An integrin/MFG-E8 shuttle loads HIV-1 viral-like particles onto follicular dendritic cells in mouse lymph node. elife. 2019;8: pubmed publisher
Benedikter B, Bouwman F, Vajen T, Heinzmann A, Grauls G, Mariman E, et al. Ultrafiltration combined with size exclusion chromatography efficiently isolates extracellular vesicles from cell culture media for compositional and functional studies. Sci Rep. 2017;7:15297 pubmed publisher
Jinushi M, Nakazaki Y, Carrasco D, Draganov D, Souders N, Johnson M, et al. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res. 2008;68:8889-98 pubmed publisher
product information
master code :
MAB27671
SKU :
MAB27671
product name :
Human MFG-E8 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human MFG-E8 Antibody from R&D Systems is a mouse monoclonal antibody to MFG-E8. This antibody reacts with human. The Human MFG-E8 Antibody has been validated for the following applications: Immunohistochemistry,Bioassay,Complex Application,Western Blot,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready.
target :
MFG-E8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
278918
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MFG-E8, Leu24-Cys387, Accession # Q08431
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human MFG-E8 in direct ELISAs and Western blots.
gene symbol :
MFGE8
top caption :
Detection of MFG-E8 antibody in Human Immature Dendritic Cells antibody by Flow Cytometry.
accessionNumbers :
Q08431
applications :
Immunohistochemistry,Bioassay,Complex Application,Western Blot,Immunohistochemistry-Paraffin,Intracellular Staining by Flow Cytometry,CyTOF-ready
USD :
489 USD
alt names :
BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, Lactahedrin, Medin, MFG1, MFGE8, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.