product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human MFG-E8 Antibody
catalog :
MAB2767
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
278901
reactivity :
human
application :
western blot
more info or order :
citations: 6
Reference
Huang F, Dai Z, Yu J, Wang K, Chen C, Chen D, et al. RBM7 deficiency promotes breast cancer metastasis by coordinating MFGE8 splicing switch and NF-kB pathway. elife. 2024;13: pubmed publisher
Kilinc S, Paisner R, Camarda R, Gupta S, Momcilovic O, Kohnz R, et al. Oncogene-regulated release of extracellular vesicles. Dev Cell. 2021;56:1989-2006.e6 pubmed publisher
Temoche Diaz M, Shurtleff M, Schekman R. Buoyant Density Fractionation of Small Extracellular Vesicle Sub-populations Derived from Mammalian Cells. Bio Protoc. 2020;10:e3706 pubmed publisher
Temoche Diaz M, Shurtleff M, Nottingham R, Yao J, Fadadu R, Lambowitz A, et al. Distinct mechanisms of microRNA sorting into cancer cell-derived extracellular vesicle subtypes. elife. 2019;8: pubmed publisher
Wang M, Fu Z, Wu J, Zhang J, Jiang L, Khazan B, et al. MFG-E8 activates proliferation of vascular smooth muscle cells via integrin signaling. Aging Cell. 2012;11:500-8 pubmed publisher
Lin Y, Hsu M, Chiou Y, Hsu H, Tsai H, Peng Y, et al. Comparative proteomic analysis of rat aorta in a subtotal nephrectomy model. Proteomics. 2010;10:2429-43 pubmed publisher
product information
master code :
MAB2767
SKU :
MAB2767
product name :
Human MFG-E8 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human MFG-E8 Antibody from R&D Systems is a mouse monoclonal antibody to MFG-E8. This antibody reacts with human. The Human MFG-E8 Antibody has been validated for the following applications: Western Blot,ELISA Development,Simple Western.
target :
MFG-E8
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
278901
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human MFG-E8, Leu24-Cys387, Accession # Q08431
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human MFG-E8 in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) C1r, rhC1s, rhC2, or rmMFG-E8.
gene symbol :
MFGE8
top caption :
Detection of Human MFG-E8 antibody by Western Blot.
accessionNumbers :
Q08431
applications :
Western Blot,ELISA Development,Simple Western
USD :
469 USD
alt names :
BA46, Breast epithelial antigen BA46, EDIL1, hP47, HsT19888, lactadherin, Lactahedrin, Medin, MFG1, MFGE8, MFG-E8, MFGM, Milk fat globule-EGF factor 8, milk fat globule-EGF factor 8 protein, O-acetyl disialoganglioside synthase, OAcGD3S, SED1, SPAG10, sperm associated antigen 10, sperm surface protein hP47
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.