Human CXCL1/2/3/GRO Pan Specific Antibody | R&D Systems MAB276-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCL1/2/3/GRO Pan Specific Antibody

catalog :

MAB276-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

459 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

31716

reactivity :

human

application :

western blot, neutralization, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 10

Reference
Zhao M, Zhang L, Sun Z, Qiao L, Yang T, Ren Y, et al. A novel microRNA-182/Interleukin-8 regulatory axis controls osteolytic bone metastasis of lung cancer. Cell Death Dis. 2023;14:298 pubmed publisher
Li A, Zhang N, Zhao Z, Chen Y, Zhang L. Overexpression of B7-H4 promotes renal cell carcinoma progression by recruiting tumor-associated neutrophils via upregulation of CXCL8. Oncol Lett. 2020;20:1535-1544 pubmed publisher
Gril B, Paranjape A, Woditschka S, Hua E, Dolan E, Hanson J, et al. Reactive astrocytic S1P3 signaling modulates the blood-tumor barrier in brain metastases. Nat Commun. 2018;9:2705 pubmed publisher
Booth J, Duggan E, Patel V, Wu W, Burian D, Hutchings D, et al. Gene expression profiling of primary human type I alveolar epithelial cells exposed to Bacillus anthracis spores reveals induction of neutrophil and monocyte chemokines. Microb Pathog. 2018;121:9-21 pubmed publisher
Puthusseri B, Marudamuthu A, Tiwari N, Fu J, Idell S, Shetty S. Regulation of p53-mediated changes in the uPA-fibrinolytic system and in lung injury by loss of surfactant protein C expression in alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2017;312:L783-L796 pubmed publisher
Kuravi S, McGettrick H, Satchell S, Saleem M, Harper L, Williams J, et al. Podocytes regulate neutrophil recruitment by glomerular endothelial cells via IL-6-mediated crosstalk. J Immunol. 2014;193:234-43 pubmed publisher
Dong Y, Kabir S, Lee E, Son D. CXCR2-driven ovarian cancer progression involves upregulation of proinflammatory chemokines by potentiating NF-?B activation via EGFR-transactivated Akt signaling. PLoS ONE. 2013;8:e83789 pubmed publisher
Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, et al. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1{alpha}, and TNF-{alpha} Recapitulates Some Features of Psoriasis. J Immunol. 2010;184:5263-5270 pubmed publisher
Hu H, Kwun J, Aizenstein B, Knechtle S. Noninvasive detection of acute and chronic injuries in human renal transplant by elevation of multiple cytokines/chemokines in urine. Transplantation. 2009;87:1814-20 pubmed publisher
Abe Y, Fornage M, Yang C, Bui Thanh N, Wise V, Chen H, et al. L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis. 2007;192:56-66 pubmed

product information

master code :

MAB276

SKU :

MAB276-100

product name :

Human CXCL1/2/3/GRO Pan Specific Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human CXCL1/2/3/GRO Pan Specific Antibody from R&D Systems is a mouse monoclonal antibody to CXCL1/2/3/GRO. This antibody reacts with human. The Human CXCL1/2/3/GRO Pan Specific Antibody has been validated for the following applications: Western Blot,Antibody Array Development,Neutralization,Immunohistochemistry-Paraffin.

target :

CXCL1/2/3/GRO

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

31716

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CXCL2, Ala35-Asn107, Accession # P19875

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CXCL1/2/3 in direct ELISAs and Western blots.

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Chemotaxis Induced by CXCL2/GROss and Neutralization by Human CXCL1/2/3/GRO Antibody.

accessionNumbers :

P19875

applications :

Antibody Array Development,Western Blot,Neutralization,Immunohistochemistry-Paraffin

USD :

459 USD

alt names :

CINC1, CINC-1, CINC-2, CINC3, CINC-3, Dcip1, FSP, Gm1960, GRO alpha, GRO beta, GRO gamma, GRO1, GROa, KC, MGSA, MGSA-a, MGSA-alpha, MGSA-beta, MIP-2, NAP-3, SCYB1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage