product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse TLR4 Antibody
catalog :
MAB2759
quantity :
100 ug (also 25 ug)
price :
469 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
267518
reactivity :
mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Mussalem J, Squaiella Baptistão C, Teixeira D, Yendo T, Thies F, Popi A, et al. Adjuvant effect of killed Propionibacterium acnes on mouse peritoneal B-1 lymphocytes and their early phagocyte differentiation. PLoS ONE. 2012;7:e33955 pubmed publisher
  • western blot; mouse; fig 7a
Xu L, Jin L, Zhang B, Akerlund L, Shu H, Cambier J. VISA is required for B cell expression of TLR7. J Immunol. 2012;188:248-58 pubmed publisher
  • western blot; mouse
Li Y, Xiang M, Yuan Y, Xiao G, Zhang J, Jiang Y, et al. Hemorrhagic shock augments lung endothelial cell activation: role of temporal alterations of TLR4 and TLR2. Am J Physiol Regul Integr Comp Physiol. 2009;297:R1670-80 pubmed publisher
Yu F, Tian W, Dong J. Anagliptin prevents lipopolysaccharide (LPS)- induced inflammation and activation of macrophages. Int Immunopharmacol. 2022;104:108514 pubmed publisher
Stojanović B, Jovanovic I, Stojanovic B, Stojanovic M, Gajovic N, Radosavljevic G, et al. Deletion of Galectin-3 attenuates acute pancreatitis in mice by affecting activation of innate inflammatory cells. Eur J Immunol. 2019;49:940-946 pubmed publisher
Lee J, Lee J, Phipps S, Noakes P, Woodruff T. Absence of toll-like receptor 4 (TLR4) extends survival in the hSOD1 G93A mouse model of amyotrophic lateral sclerosis. J Neuroinflammation. 2015;12:90 pubmed publisher
Yano J, Palmer G, Eberle K, Peters B, Vogl T, McKenzie A, et al. Vaginal epithelial cell-derived S100 alarmins induced by Candida albicans via pattern recognition receptor interactions are sufficient but not necessary for the acute neutrophil response during experimental vaginal candidiasis. Infect Immun. 2014;82:783-92 pubmed publisher
Chen J, John R, Richardson J, Shelton J, Zhou X, Wang Y, et al. Toll-like receptor 4 regulates early endothelial activation during ischemic acute kidney injury. Kidney Int. 2011;79:288-99 pubmed publisher
product information
master code :
MAB2759
SKU :
MAB2759
product name :
Mouse TLR4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse TLR4 Antibody from R&D Systems is a rat monoclonal antibody to TLR4. This antibody reacts with mouse. The Mouse TLR4 Antibody has been validated for the following applications: Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.
target :
TLR4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
267518
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
Mouse myeloma cell line NS0-derived recombinant mouse TLR4, Asn26-Lys629, Accession # Q9QUK6
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse TLR4 in direct ELISAs. In direct ELISAs, does not cross-react with recombinant mouse TLR1, 2, 3, 6, or recombinant human TLR4.
gene symbol :
TLR4
top caption :
TLR4 antibody in RAW 264 by Immunocytochemistry (ICC).7 Mouse Monocyte/Macrophage Cell Line by Immunocytochemistry (ICC).
accessionNumbers :
Q9QUK6
applications :
Flow Cytometry,Western Blot,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready
USD :
469 USD
alt names :
ARMD10, CD_antigen: CD284, CD284, CD284 antigen, EC 3.2.2.6, EC:3.2.2.6, homolog of Drosophila toll, hToll, TLR4, TLR-4, TOLL, toll like receptor 4 protein, toll-like receptor 4
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.