Human CD27 Ligand/TNFSF7 Antibody | R&D Systems MAB2738 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CD27 Ligand/TNFSF7 Antibody

catalog :

MAB2738

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

301731

reactivity :

human, mouse

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

R&D Systems product webpage

citations: 9

Reference
Acharya S, Basar R, Daher M, Rafei H, Li P, Uprety N, et al. CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis. Cancer Discov. 2024;14:1879-1900 pubmed publisher
Van den Eynde A, Gehrcken L, Verhezen T, Lau H, Hermans C, Lambrechts H, et al. IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts. J Hematol Oncol. 2024;17:8 pubmed publisher
Huang R, Chen Z, Kroeger N, Pantuck A, Said J, Kluger H, et al. CD70 is Consistently Expressed in Primary and Metastatic Clear Cell Renal Cell Carcinoma. Clin Genitourin Cancer. 2024;22:347-353 pubmed publisher
Nie M, Ren W, Ye X, Berglund M, Wang X, Fjord xe9 n K, et al. The dual role of CD70 in B-cell lymphomagenesis. Clin Transl Med. 2022;12:e1118 pubmed publisher
Tourigny D, Zucker M, Kim M, Russo P, Coleman J, Lee C, et al. Molecular Characterization of the Tumor Microenvironment in Renal Medullary Carcinoma. Front Oncol. 2022;12:910147 pubmed publisher
Shiomi M, Matsuzaki S, Serada S, Matsuo K, Mizuta Odani C, Jitsumori M, et al. CD70 antibody-drug conjugate: A potential novel therapeutic agent for ovarian cancer. Cancer Sci. 2021;112:3655-3668 pubmed publisher
Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, et al. CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma. Am J Obstet Gynecol. 2021;224:197.e1-197.e23 pubmed publisher
Flieswasser T, Camara Clayette V, Danu A, Bosq J, Ribrag V, Zabrocki P, et al. Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method. Cancers (Basel). 2019;11: pubmed publisher
Miikkulainen P, Högel H, Rantanen K, Suomi T, Kouvonen P, Elo L, et al. HIF prolyl hydroxylase PHD3 regulates translational machinery and glucose metabolism in clear cell renal cell carcinoma. Cancer Metab. 2017;5:5 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB2738

SKU :

MAB2738

product name :

Human CD27 Ligand/TNFSF7 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human CD27 Ligand/TNFSF7 Antibody from R&D Systems is a mouse monoclonal antibody to CD27 Ligand/TNFSF7/CD70. This antibody reacts with human,mouse. The Human CD27 Ligand/TNFSF7 Antibody has been validated for the following applications: Immunohistochemistry,Immunohistochemistry-Paraffin,Flow Cytometry.

target :

CD27 Ligand/TNFSF7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

301731

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Flow Cytometry 0.25 ug/10^6 cells

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CD27 Ligand/TNFSF7, Gln45-Pro193, Accession # AAA36175

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human CD27 Ligand/TNFSF7 in direct ELISAs.

gene symbol :

CD70

top caption :

Detection of CD27Ligand/TNFSF7 antibody in HEK293 Human Cell Line Transfected with Human CD27 Ligand/TNFSF7 antibody by Flow Cytometry.

accessionNumbers :

AAA36175

applications :

Flow Cytometry,Immunohistochemistry,Immunohistochemistry-Paraffin

USD :

489 USD

alt names :

CD27-L, CD27LCD27 ligand, CD27LG, CD70, CD70 molecule, Ki-24 antigen, surface antigen CD70, TNFSF7, TNFSF7CD70 antigen, tumor necrosis factor (ligand) superfamily, member 7, Tumor necrosis factor ligand superfamily member 7

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage