This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human CCL3/CCL4 Antibody
catalog :
MAB270
quantity :
100 ug (also 25 ug, 500 ug)
price :
359 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
93321
reactivity :
human
application :
western blot, immunocytochemistry, neutralization, other
citations: 9
Published Application/Species/Sample/DilutionReference
  • other; human; fig s1
Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
Sun W, Meednu N, Rosenberg A, Rangel Moreno J, Wang V, Glanzman J, et al. B cells inhibit bone formation in rheumatoid arthritis by suppressing osteoblast differentiation. Nat Commun. 2018;9:5127 pubmed publisher
Auclair S, Liu F, Niu Q, Hou W, Churchyard G, Morgan C, et al. Distinct susceptibility of HIV vaccine vector-induced CD4 T cells to HIV infection. PLoS Pathog. 2018;14:e1006888 pubmed publisher
Rump L, Mattey D, Kehoe O, Middleton J. An initial investigation into endothelial CC chemokine expression in the human rheumatoid synovium. Cytokine. 2017;97:133-140 pubmed publisher
Baldwin H, Singh M, Codullo V, King V, Wilson H, McInnes I, et al. Elevated ACKR2 expression is a common feature of inflammatory arthropathies. Rheumatology (Oxford). 2017;56:1607-1617 pubmed publisher
Kanegasaki S, Matsushima K, Shiraishi K, Nakagawa K, Tsuchiya T. Macrophage inflammatory protein derivative ECI301 enhances the alarmin-associated abscopal benefits of tumor radiotherapy. Cancer Res. 2014;74:5070-8 pubmed publisher
Snyder Cappione J, Tincati C, Eccles James I, Cappione A, Ndhlovu L, Koth L, et al. A comprehensive ex vivo functional analysis of human NKT cells reveals production of MIP1-? and MIP1-?, a lack of IL-17, and a Th1-bias in males. PLoS ONE. 2010;5:e15412 pubmed publisher
Franciszkiewicz K, Le Floc h A, Jalil A, Vigant F, Robert T, Vergnon I, et al. Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. Cancer Res. 2009;69:6249-55 pubmed publisher
Fischer J, West J, Agochukwu N, Suire C, Hale Donze H. Induction of host chemotactic response by Encephalitozoon spp. Infect Immun. 2007;75:1619-25 pubmed
product information
brand :
R&D Systems
master code :
MAB270
SKU :
MAB270-100
product name :
Human CCL3/CCL4 Antibody
description :
The Human CCL3/CCL4 Antibody from R&D Systems is a mouse monoclonal antibody to CCL3/CCL4. This antibody reacts with human. The Human CCL3/CCL4 Antibody has been validated for the following applications: Western Blot, Neutralization, Immunocytochemistry.
target :
CCL3/CCL4
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
93321
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human CCL3/MIP-1 alpha , Ala27-Ala92, Accession # P10147
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human
specificity :
Detects human CCL3/MIP-1 alpha in direct ELISAs and Western blots. In direct ELISAs, greater than 75% cross-reactivity with recombinant human (rh) CCL4/MIP-1 beta is observed while approximately 30% cross-reactivity with recombinant mouse (rm) CCL3, rmCCL4/MIP-1 beta , and rhCCL14 is observed. No cross-reactivity with rhCCL1, 2, 5, 7, 8, 11, 13, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, rmCCL1, 2, 5, 6, 7, 9/10/MIP-1 gamma , 11, 12, 17, 19, 20, 21, 22, 24, 25, or recombinant rat CCL20 is observed.
gene symbol :
CCL3
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB270
accessionNumbers :
P10147
applications :
Western Blot, Neutralization, Immunocytochemistry
2020 USD :
339
2021 USD :
359 USD
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.