product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NT-3 Antibody
catalog :
MAB267-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
41512
reactivity :
human
application :
ELISA, immunocytochemistry, neutralization
more info or order :
R&D Systems product webpage
citations: 4
Reference
Sahenk Z, Galloway G, Clark K, Malik V, Rodino Klapac L, Kaspar B, et al. AAV1.NT-3 gene therapy for charcot-marie-tooth neuropathy. Mol Ther. 2014;22:511-521 pubmed publisher
Bouzas Rodriguez J, Cabrera J, Delloye Bourgeois C, Ichim G, Delcros J, Raquin M, et al. Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis. J Clin Invest. 2010;120:850-8 pubmed publisher
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed publisher
Nassenstein C, Braun A, Erpenbeck V, Lommatzsch M, Schmidt S, Krug N, et al. The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma. J Exp Med. 2003;198:455-67 pubmed
product information
brand :
R&D Systems
master code :
MAB267
SKU :
MAB267-100
product name :
Human NT-3 Antibody
unit size :
100 ug (also 25 ug, 500 ug)
seo description :
The Human NT-3 Antibody from R&D Systems is a mouse monoclonal antibody to NT-3. This antibody reacts with human. The Human NT-3 Antibody has been validated for the following applications: ELISA Development,ELISA Development (Capture),Neutralization,Immunocytochemistry,ELISA Capture (Matched Antibody Pair).
target :
NT-3
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
41512
conjugate :
Unconjugated
dilution :
Neutralization 0.1-0.5 ug/mL, ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human NT-3, Tyr139-Thr257, Accession # P20783
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human NT-3 in ELISAs. In sandwich immunoassays, no cross-reactivity with recombinant human (rh) BDNF, rhCNTF, rhGDNF, rh▀-NGF, and rhNT-4 is observed.
gene symbol :
NTF3
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by NT-3 and Neutralization by Human NT-3 Antibody.
accessionNumbers :
P20783
applications :
ELISA Capture (Matched Antibody Pair),ELISA Development,ELISA Development (Capture),Neutralization,Immunocytochemistry
USD :
469 USD
alt names :
HDNF, MGC129711, Nerve growth factor 2, Neurotrophic factor, neurotrophin 3, neurotrophin-3, NGF2, NGF-2, NT3, NT-3, NTF3
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
R&D Systems product webpage
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.