Human CXCL10/IP-10/CRG-2 Antibody | R&D Systems MAB266 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human CXCL10/IP-10/CRG-2 Antibody

catalog :

MAB266

quantity :

100 ug (also 25 ug, 500 ug)

price :

369 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

33036

reactivity :

human

application :

neutralization, other

citations: 32

Published Application/Species/Sample/Dilution	Reference
ELISA; human; loading ...; tbl s7	Bouhaddou M, Memon D, Meyer B, White K, Rezelj V, Correa Marrero M, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020;182:685-712.e19 pubmed publisher
other; human; loading ...; fig s1	Shah F, Stepan A, O Mahony A, Velichko S, Folias A, Houle C, et al. Mechanisms of Skin Toxicity Associated with Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators. Cell Chem Biol. 2017;24:858-869.e5 pubmed publisher
	Nishina S, Yamauchi A, Kawaguchi T, Kaku K, Goto M, Sasaki K, et al. Dipeptidyl Peptidase 4 Inhibitors Reduce Hepatocellular Carcinoma by Activating Lymphocyte Chemotaxis in Mice. Cell Mol Gastroenterol Hepatol. 2019;7:115-134 pubmed publisher
	Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
	Connelly K, Kandane Rathnayake R, Hoi A, Nikpour M, Morand E. Association of MIF, but not type I interferon-induced chemokines, with increased disease activity in Asian patients with systemic lupus erythematosus. Sci Rep. 2016;6:29909 pubmed publisher
	Schutte K, Fisher D, Burdick M, Mehrad B, Mathers A, Mann B, et al. Escherichia coli Pyruvate Dehydrogenase Complex Is an Important Component of CXCL10-Mediated Antimicrobial Activity. Infect Immun. 2016;84:320-8 pubmed publisher
	Pinto S, Martinez Romero A, O Connor J, Gil Benso R, San Miguel T, Terrádez L, et al. Intracellular coexpression of CXC- and CC- chemokine receptors and their ligands in human melanoma cell lines and dynamic variations after xenotransplantation. BMC Cancer. 2014;14:118 pubmed publisher
	Karta M, Wickert L, Curran C, Gavala M, Denlinger L, Gern J, et al. Allergen challenge in vivo alters rhinovirus-induced chemokine secretion from human airway macrophages. J Allergy Clin Immunol. 2014;133:1227-1230.e4 pubmed publisher
	Zaheer R, Wiehler S, Hudy M, Traves S, Pelikan J, Leigh R, et al. Human rhinovirus-induced ISG15 selectively modulates epithelial antiviral immunity. Mucosal Immunol. 2014;7:1127-38 pubmed publisher
	Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, et al. Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients. Clin Cancer Res. 2013;19:1858-72 pubmed publisher
	Nakajima N, Van Tin N, Sato Y, Thach H, Katano H, Diep P, et al. Pathological study of archival lung tissues from five fatal cases of avian H5N1 influenza in Vietnam. Mod Pathol. 2013;26:357-69 pubmed publisher
	Xu W, Joo H, Clayton S, Dullaers M, Herve M, Blankenship D, et al. Macrophages induce differentiation of plasma cells through CXCL10/IP-10. J Exp Med. 2012;209:1813-23, S1-2 pubmed
	Zahn S, Rehkämper C, Kummerer B, Ferring Schmidt S, Bieber T, Tüting T, et al. Evidence for a pathophysiological role of keratinocyte-derived type III interferon (IFN?) in cutaneous lupus erythematosus. J Invest Dermatol. 2011;131:133-40 pubmed publisher
	Oo Y, Weston C, Lalor P, Curbishley S, Withers D, Reynolds G, et al. Distinct roles for CCR4 and CXCR3 in the recruitment and positioning of regulatory T cells in the inflamed human liver. J Immunol. 2010;184:2886-98 pubmed publisher
	Yoon K, Park C, You I, Choi H, Lee K, Im S, et al. Expression of CXCL9, -10, -11, and CXCR3 in the tear film and ocular surface of patients with dry eye syndrome. Invest Ophthalmol Vis Sci. 2010;51:643-50 pubmed publisher
	Franciszkiewicz K, Le Floc h A, Jalil A, Vigant F, Robert T, Vergnon I, et al. Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. Cancer Res. 2009;69:6249-55 pubmed publisher
	Biancotto A, Iglehart S, Lisco A, Vanpouille C, Grivel J, Lurain N, et al. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res Hum Retroviruses. 2008;24:453-62 pubmed publisher
	Qui H, Ferrell E, Nolan N, Phelps B, Tabibiazar R, Whitney D, et al. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines. Clin Chem. 2007;53:2010-2 pubmed
	Pfleger C, Schloot N, ter Veld F. Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J Immunol Methods. 2008;329:214-8 pubmed
	Cheadle E, Riyad K, Subar D, Rothwell D, Ashton G, Batha H, et al. Eotaxin-2 and colorectal cancer: a potential target for immune therapy. Clin Cancer Res. 2007;13:5719-28 pubmed
	Liu L, Bates M, Jarjour N, Busse W, Bertics P, Kelly E. Generation of Th1 and Th2 chemokines by human eosinophils: evidence for a critical role of TNF-alpha. J Immunol. 2007;179:4840-8 pubmed
	Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, et al. Down-modulation of CXCR3 surface expression and function in CD8+ T cells from cutaneous T cell lymphoma patients. J Immunol. 2007;179:4272-82 pubmed
	Grivel J, Elliott J, Lisco A, Biancotto A, Condack C, Shattock R, et al. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1. AIDS. 2007;21:1263-72 pubmed
	Biancotto A, Grivel J, Iglehart S, Vanpouille C, Lisco A, Sieg S, et al. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood. 2007;109:4272-9 pubmed
	Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck L, et al. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines. Clin Immunol. 2006;120:220-31 pubmed
	Edwards M, Johnson M, Johnston S. Combination therapy: Synergistic suppression of virus-induced chemokines in airway epithelial cells. Am J Respir Cell Mol Biol. 2006;34:616-24 pubmed
	Wenzel J, Wörenkämper E, Freutel S, Henze S, Haller O, Bieber T, et al. Enhanced type I interferon signalling promotes Th1-biased inflammation in cutaneous lupus erythematosus. J Pathol. 2005;205:435-42 pubmed
	Sui Y, Li S, Pinson D, Adany I, Li Z, Villinger F, et al. Simian human immunodeficiency virus-associated pneumonia correlates with increased expression of MCP-1, CXCL10, and viral RNA in the lungs of rhesus macaques. Am J Pathol. 2005;166:355-65 pubmed
	Kohrgruber N, Groger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, et al. Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. J Immunol. 2004;173:6592-602 pubmed
	Øynebråten I, Bakke O, Brandtzaeg P, Johansen F, Haraldsen G. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments. Blood. 2004;104:314-20 pubmed
	Hurst S, McLoughlin R, Monslow J, Owens S, Morgan L, Fuller G, et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol. 2002;169:5244-51 pubmed
	Lauw F, Dekkers P, te Velde A, Speelman P, Levi M, Kurimoto M, et al. Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees. J Infect Dis. 1999;179:646-52 pubmed

product information

brand :

R&D Systems

master code :

MAB266

SKU :

MAB266-100

product name :

Human CXCL10/IP-10/CRG-2 Antibody

description :

The Human CXCL10/IP-10/CRG-2 Antibody from R&D Systems is a mouse monoclonal antibody to CXCL10/IP-10/CRG-2. This antibody reacts with human. The Human CXCL10/IP-10/CRG-2 Antibody has been validated for the following applications: Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair).

target :

CXCL10/IP-10/CRG-2

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

33036

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human CXCL10/IP-10/CRG-2, Val22-Pro98, Accession # P02778.2

isotype :

IgG1

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human CXCL10/IP-10/CRG-2 in ELISAs.

gene symbol :

CXCL10

details of functionality :

ActivityAssaywCitation not found None None None

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB266

accessionNumbers :

P02778.2

applications :

Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

369 USD

alt names :

C7, chemokine (C-X-C motif) ligand 10, crg-2, CRG2, gIP-10, IFI10, INP10, IP-10, mob-1, SCYB10

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.