product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human IL-1 RII Antibody
catalog :
MAB263
quantity :
500 ug (also 25 ug)
price :
559 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
32437
reactivity :
human
application :
western blot, immunocytochemistry, neutralization, immunohistochemistry - frozen section
more info or order :
citations: 3
Reference
Kim D, Kim H, Cho S, Yoo S, Kim W, Yeon H, et al. Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells. elife. 2021;10: pubmed publisher
Takao T, Asanoma K, Kato K, Fukushima K, Tsunematsu R, Hirakawa T, et al. Isolation and characterization of human trophoblast side-population (SP) cells in primary villous cytotrophoblasts and HTR-8/SVneo cell line. PLoS ONE. 2011;6:e21990 pubmed publisher
Grundtman C, Salomonsson S, Dorph C, Bruton J, Andersson U, Lundberg I. Immunolocalization of interleukin-1 receptors in the sarcolemma and nuclei of skeletal muscle in patients with idiopathic inflammatory myopathies. Arthritis Rheum. 2007;56:674-87 pubmed
product information
master code :
MAB263
SKU :
MAB263
product name :
Human IL-1 RII Antibody
unit size :
500 ug (also 25 ug)
description :
The Human IL-1 RII Antibody from R&D Systems is a mouse monoclonal antibody to IL-1 RII. This antibody reacts with human. The Human IL-1 RII Antibody has been validated for the following applications: Neutralization,Western Blot,Cell Selection,Immunohistochemistry-Frozen,Immunocytochemistry.
target :
IL-1 RII
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
32437
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IL-1 RII, Phe14-Glu343 (Glu297Gly), Accession # P27930
isotype :
IgG2a
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human IL-1 RII in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-1 RI, rhIL-18 R, and recombinant mouse IL-18 R is observed.
gene symbol :
IL1R2
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
IL-1 RII Inhibition of IL-1ss/IL-1F2-dependent Cell Proliferation and Neutralization by Human IL-1 RII Antibody.
accessionNumbers :
P27930
applications :
Western Blot,Cell Selection,Immunohistochemistry-Frozen,Immunocytochemistry,Neutralization
USD :
559 USD
alt names :
beta, CD121b, CD121b antigen, IL-1 R beta, IL1R2, IL1RBCD121 antigen-like family member B, IL-1R-beta, IL1RII, IL-1RII, IL-1RT2, IL-1RT-2, interleukin 1 receptor, type II, Interleukin-1 receptor beta, MGC47725
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.