Mouse FGF-23 Antibody | R&D Systems MAB26291 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Mouse FGF-23 Antibody

catalog :

MAB26291

quantity :

100 ug (also 25 ug)

price :

429 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

283507

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 23

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; loading ...; fig 1f western blot; mouse; loading ...; fig 1e	Radhakrishnan K, Kim Y, Jung Y, Kim D, Na S, Lim D, et al. Orphan nuclear receptor ERR-γ regulates hepatic FGF23 production in acute kidney injury. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
	Aobulikasimu A, Liu T, Piao J, Sato S, Ochi H, Okawa A, et al. SIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption. Sci Rep. 2023;13:7991 pubmed publisher
	Hasegawa T, Tokunaga S, Yamamoto T, Sakai M, Hongo H, Kawata T, et al. Evocalcet Rescues Secondary Hyperparathyroidism-driven Cortical Porosity in CKD Male Rats. Endocrinology. 2023;164: pubmed publisher
	Hurley M, Coffin J, Doetschman T, Valera C, Clarke K, Xiao L. FGF receptor inhibitor BGJ398 partially rescues osteoarthritis-like phenotype in older high molecular weight FGF2 transgenic mice via multiple mechanisms. Sci Rep. 2022;12:15968 pubmed publisher
	Millington G, Joseph J, Xiao L, Vijaykumar A, Mina M, Hurley M. Fibroblast Growth Factor 2 High Molecular Weight Isoforms in Dentoalveolar Mineralization. Calcif Tissue Int. 2022;110:93-103 pubmed publisher
	Dixit M, Duran Ortiz S, Yildirim G, Poudel S, Louis L, Bartke A, et al. Induction of somatopause in adult mice compromises bone morphology and exacerbates bone loss during aging. Aging Cell. 2021;20:e13505 pubmed publisher
	Ursem S, Diepenbroek C, Bacic V, Unmehopa U, Eggels L, Maya Monteiro C, et al. Localization of fibroblast growth factor 23 protein in the rat hypothalamus. Eur J Neurosci. 2021;54:5261-5271 pubmed publisher
	Kawai M, Kinoshita S, Ozono K, Michigami T. Lack of PTEN in osteocytes increases circulating phosphate concentrations by decreasing intact fibroblast growth factor 23 levels. Sci Rep. 2020;10:21501 pubmed publisher
	Laszczyk A, Nettles D, Pollock T, Fox S, Garcia M, Wang J, et al. FGF-23 Deficiency Impairs Hippocampal-Dependent Cognitive Function. Eneuro. 2019;6: pubmed publisher
	Burt P, Xiao L, Doetschman T, Hurley M. Ablation of low-molecular-weight FGF2 isoform accelerates murine osteoarthritis while loss of high-molecular-weight FGF2 isoforms offers protection. J Cell Physiol. 2019;234:4418-4431 pubmed publisher
	Sugiura H, Matsushita A, Futaya M, Teraoka A, Akiyama K, Usui N, et al. Fibroblast growth factor 23 is upregulated in the kidney in a chronic kidney disease rat model. PLoS ONE. 2018;13:e0191706 pubmed publisher
	Sakurai A, Hasegawa T, Kudo A, Shen Z, Nagai T, Abe M, et al. Chronological immunolocalization of sclerostin and FGF23 in the mouse metaphyseal trabecular and cortical bone. Biomed Res. 2017;38:257-267 pubmed publisher
	Fischer V, Haffner Luntzer M, Prystaz K, vom Scheidt A, Busse B, Schinke T, et al. Calcium and vitamin-D deficiency marginally impairs fracture healing but aggravates posttraumatic bone loss in osteoporotic mice. Sci Rep. 2017;7:7223 pubmed publisher
	Kamiya N, Yamaguchi R, Aruwajoye O, Kim A, Kuroyanagi G, Phipps M, et al. Targeted Disruption of NF1 in Osteocytes Increases FGF23 and Osteoid With Osteomalacia-like Bone Phenotype. J Bone Miner Res. 2017;32:1716-1726 pubmed publisher
	Liu Y, Dutra E, REICHENBERGER E, Chen I. Dietary phosphate supplement does not rescue skeletal phenotype in a mouse model for craniometaphyseal dysplasia. J Negat Results Biomed. 2016;15:18 pubmed
	Liu Z, Yamamoto T, Hasegawa T, Hongo H, Tsuboi K, Tsuchiya E, et al. Immunolocalization of osteocyte-derived molecules during bone fracture healing of mouse ribs. Biomed Res. 2016;37:141-51 pubmed publisher
	Paloian N, Leaf E, Giachelli C. Osteopontin protects against high phosphate-induced nephrocalcinosis and vascular calcification. Kidney Int. 2016;89:1027-1036 pubmed publisher
	Bai X, Miao D, Xiao S, Qiu D, St Arnaud R, Petkovich M, et al. CYP24 inhibition as a therapeutic target in FGF23-mediated renal phosphate wasting disorders. J Clin Invest. 2016;126:667-80 pubmed publisher
	Yamamoto H, Ramos Molina B, Lick A, Prideaux M, Albornoz V, Bonewald L, et al. Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition. Bone. 2016;84:120-130 pubmed publisher
	Fang Y, Ginsberg C, Seifert M, Agapova O, Sugatani T, Register T, et al. CKD-induced wingless/integration1 inhibitors and phosphorus cause the CKD-mineral and bone disorder. J Am Soc Nephrol. 2014;25:1760-73 pubmed publisher
	Spichtig D, Zhang H, Mohebbi N, Pavik I, Petzold K, Stange G, et al. Renal expression of FGF23 and peripheral resistance to elevated FGF23 in rodent models of polycystic kidney disease. Kidney Int. 2014;85:1340-50 pubmed publisher
	Fang Y, Ginsberg C, Sugatani T, Monier Faugere M, Malluche H, Hruska K. Early chronic kidney disease-mineral bone disorder stimulates vascular calcification. Kidney Int. 2014;85:142-50 pubmed publisher
	Gore M, Welch B, Geng W, Kabbani W, Maalouf N, Zerwekh J, et al. Renal phosphate wasting due to tumor-induced osteomalacia: a frequently delayed diagnosis. Kidney Int. 2009;76:342-7 pubmed publisher

product information

master code :

MAB26291

SKU :

MAB26291

product name :

Mouse FGF-23 Antibody

unit size :

100 ug (also 25 ug)

description :

The Mouse FGF-23 Antibody from R&D Systems is a rat monoclonal antibody to FGF-23. This antibody reacts with human,mouse,rat,transgenic mouse. The Mouse FGF-23 Antibody has been validated for the following applications: Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

FGF-23

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

283507

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse FGF-23, Tyr25-Val251 (Arg179Gln), Accession # Q9EPC2

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects mouse FGF-23 in direct ELISAs and Western blots. In direct ELISAs, this antibody shows approximately 50% cross-reactivity with recombinant human (rh) FGF-23. In Western blots, this antibody does not cross-react with rhFGF-3, -4, -5, -7, -9, -10, -11, -12, -13, -16, -17, -18, -19, acidic, basic, rmFGF-8b, -8c, -15, or -21.

gene symbol :

Fgf23

top caption :

FGF-23 antibody in Mouse Brain by Immunohistochemistry (IHC-P) by Immunohistochemistry (IHC-Fr).

accessionNumbers :

Q9EPC2

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry

USD :

429 USD

alt names :

ADHR, FGF23, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage