Human/Mouse FGF-23 Antibody | R&D Systems MAB2629 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse FGF-23 Antibody

catalog :

MAB2629

quantity :

100 ug (also 25 ug)

price :

439 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

283511

reactivity :

human, mouse

application :

western blot, immunohistochemistry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Kishimoto H, Nakano T, Torisu K, Tokumoto M, Uchida Y, Yamada S, et al. Indoxyl sulfate induces left ventricular hypertrophy via the AhR-FGF23-FGFR4 signaling pathway. Front Cardiovasc Med. 2023;10:990422 pubmed publisher
Quarto N, Shailendra S, Meyer N, Menon S, Renda A, Longaker M. Twist1-Haploinsufficiency Selectively Enhances the Osteoskeletal Capacity of Mesoderm-Derived Parietal Bone Through Downregulation of Fgf23. Front Physiol. 2018;9:1426 pubmed publisher
Smith E, Tan S, Holt S, Hewitson T. FGF23 is synthesised locally by renal tubules and activates injury-primed fibroblasts. Sci Rep. 2017;7:3345 pubmed publisher
Xiao Z, Riccardi D, Velazquez H, Chin A, Yates C, Carrick J, et al. A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia. Sci Signal. 2016;9:ra113 pubmed
Xiao Z, Huang J, Cao L, Liang Y, Han X, Quarles L. Osteocyte-specific deletion of Fgfr1 suppresses FGF23. PLoS ONE. 2014;9:e104154 pubmed publisher
Takaiwa M, Aya K, Miyai T, Hasegawa K, Yokoyama M, Kondo Y, et al. Fibroblast growth factor 23 concentrations in healthy term infants during the early postpartum period. Bone. 2010;47:256-62 pubmed

product information

master code :

MAB2629

SKU :

MAB2629

product name :

Human/Mouse FGF-23 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human/Mouse FGF-23 Antibody from R&D Systems is a rat monoclonal antibody to FGF-23. This antibody reacts with human,mouse. The Human/Mouse FGF-23 Antibody has been validated for the following applications: Co-Immunoprecipitation,Western Blot,Immunohistochemistry.

target :

FGF-23

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

283511

concentration :

LYOPH

conjugate :

Unconjugated

host :

Rat

immunogen :

Mouse myeloma cell line NS0-derived recombinant mouse FGF-23, Tyr25-Val251 (Arg179Gln), Accession # Q9EPC2

isotype :

IgG2b

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse FGF-23 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) FGF acidic, rhFGF basic, rhFGF-3, -4, -5, -6, -7, -9, -10, -11, -12, -13, -16, -17, -18, -19, -20, -21, recombinant mouse (rm) FGF-8b, rmFGF-8c, or rmFGF-15.

gene symbol :

FGF23

top caption :

Detection of Mouse FGF-23 by Western Blot

accessionNumbers :

Q9EPC2

applications :

Co-Immunoprecipitation,Western Blot,Immunohistochemistry

USD :

439 USD

alt names :

ADHR, FGF23, FGF-23, fibroblast growth factor 23, HPDR2, HYPF, Phosphatonin, PHPTC, tumor-derived hypophosphatemia inducing factor, Tumor-derived hypophosphatemia-inducing factor

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage