product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human HB-EGF Antibody
catalog :
MAB2591-100
quantity :
100 ug (also 25 ug, 500 ug)
price :
469 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
406316
reactivity :
human, rat
application :
western blot, neutralization
more info or order :
citations: 3
Reference
Bauer L, Edwards J, Heil A, Dewitt S, Biebermann H, Aeschlimann D, et al. Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) Signalling. Int J Mol Sci. 2024;25: pubmed publisher
Müller Deubert S, Seefried L, Krug M, Jakob F, Ebert R. Epidermal growth factor as a mechanosensitizer in human bone marrow stromal cells. Stem Cell Res. 2017;24:69-76 pubmed publisher
Casas González P, García Sáinz J. Role of epidermal growth factor receptor transactivation in alpha1B-adrenoceptor phosphorylation. Eur J Pharmacol. 2006;542:31-6 pubmed
product information
master code :
MAB2591
SKU :
MAB2591-100
product name :
Human HB-EGF Antibody
unit size :
100 ug (also 25 ug, 500 ug)
description :
The Human HB-EGF Antibody from R&D Systems is a mouse monoclonal antibody to HB-EGF. This antibody reacts with human,rat. The Human HB-EGF Antibody has been validated for the following applications: Neutralization,Functional Assay,Western Blot.
target :
HB-EGF
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
406316
conjugate :
Unconjugated
host :
Mouse
immunogen :
S. frugiperda insect ovarian cell line Sf 21-derived recombinant human HB-EGF, Asp63-Leu148, Accession # Q53H93
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Rat
specificity :
Detects human HB-EGF in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody does not cross-react with recombinant human (rh) Amphiregulin, rhBTC, rhHRG-alpha , rhHRG┐▀, rhEGF, rhTGF-alpha , recombinant mouse (rm) Epigen, or rmEpiregulin.
gene symbol :
HBEGF
endotoxin note :
<0.10 EU per 1 ╡g of the antibody by the LAL method.
top caption :
Cell Proliferation Induced by HB-EGF and Neutralization by Human HB-EGF Antibody.
accessionNumbers :
Q53H93
applications :
Neutralization,Functional Assay,Western Blot
USD :
469 USD
alt names :
diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor), Dtr, DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor), Dts, DTSF, HBEGF, Hegfl, heparin-binding EGF-like growth factor, heparin-binding epidermal growth factor, proheparin-binding EGF-like growth factor
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.