product summary
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company name :
R&D Systems
product type :
antibody
product name :
Mouse ULBP-1/MULT-1 Antibody
catalog :
MAB2588
quantity :
100 ug (also 25 ug)
price :
439 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
237104
reactivity :
mouse
application :
western blot, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 18
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 7d
Sauer M, Schuldner M, Hoffmann N, Cetintas A, Reiners K, Shatnyeva O, et al. CBP/p300 acetyltransferases regulate the expression of NKG2D ligands on tumor cells. Oncogene. 2017;36:933-941 pubmed publisher
  • flow cytometry; mouse
Jung H, Hsiung B, Pestal K, Procyk E, Raulet D. RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry. J Exp Med. 2012;209:2409-22 pubmed publisher
  • flow cytometry; mouse
Lundqvist A, Yokoyama H, Smith A, Berg M, Childs R. Bortezomib treatment and regulatory T-cell depletion enhance the antitumor effects of adoptively infused NK cells. Blood. 2009;113:6120-7 pubmed publisher
  • flow cytometry; mouse
Kotturi H, Li J, Branham O Connor M, Stickel S, Yu X, Wagner T, et al. Tumor cells expressing a fusion protein of MULT1 and Fas are rejected in vivo by apoptosis and NK cell activation. Gene Ther. 2008;15:1302-10 pubmed publisher
  • flow cytometry; mouse
Vilarinho S, Ogasawara K, Nishimura S, Lanier L, Baron J. Blockade of NKG2D on NKT cells prevents hepatitis and the acute immune response to hepatitis B virus. Proc Natl Acad Sci U S A. 2007;104:18187-92 pubmed
Zhang H, Tang Q, Miao Y, Wang J, Yuan Z, Huang X, et al. Group 1 innate lymphoid cell activation via recognition of NKG2D and liver resident macrophage MULT-1: Collaborated roles in triptolide induced hepatic immunotoxicity in mice. Ecotoxicol Environ Saf. 2024;272:116072 pubmed publisher
D Alessandro G, Antonangeli F, Marrocco F, Porzia A, Lauro C, Santoni A, et al. Gut microbiota alterations affect glioma growth and innate immune cells involved in tumor immunosurveillance in mice. Eur J Immunol. 2020;50:705-711 pubmed publisher
Nakamura Y, Miyagawa S, Yoshida S, Sasawatari S, Toyofuku T, Toda K, et al. Natural killer cells impede the engraftment of cardiomyocytes derived from induced pluripotent stem cells in syngeneic mouse model. Sci Rep. 2019;9:10840 pubmed publisher
Alvarez M, Simonetta F, Baker J, Pierini A, Wenokur A, Morrison A, et al. Regulation of murine NK cell exhaustion through the activation of the DNA damage repair pathway. JCI Insight. 2019;5: pubmed publisher
Ma L, Han M, Keyoumu Z, Wang H, Keyoumu S. Immunotherapy of Dual-Function Vector with Both Immunostimulatory and B-Cell Lymphoma 2 (Bcl-2)-Silencing Effects on Gastric Carcinoma. Med Sci Monit. 2017;23:1980-1991 pubmed
Hua L, Fang M, Dong B, Guo S, Cui C, Liu J, et al. Attribution of NKG2DL to the inhibition of early stage allogeneic tumors in mice. Oncotarget. 2016;7:82369-82383 pubmed publisher
Luci C, Bekri S, Bihl F, Pini J, Bourdely P, Nouhen K, et al. NKp46+ Innate Lymphoid Cells Dampen Vaginal CD8 T Cell Responses following Local Immunization with a Cholera Toxin-Based Vaccine. PLoS ONE. 2015;10:e0143224 pubmed publisher
Nielsen M, Dyring Andersen B, Schmidt J, Witherden D, Lovato P, Woetmann A, et al. NKG2D-dependent activation of dendritic epidermal T cells in contact hypersensitivity. J Invest Dermatol. 2015;135:1311-1319 pubmed publisher
Tietje A, Li J, Yu X, Wei Y. MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation. Gene Ther. 2014;21:468-75 pubmed publisher
Paolino M, Choidas A, Wallner S, Pranjic B, Uribesalgo I, Loeser S, et al. The E3 ligase Cbl-b and TAM receptors regulate cancer metastasis via natural killer cells. Nature. 2014;507:508-12 pubmed publisher
Yoshida S, Mohamed R, Kajikawa M, Koizumi J, Tanaka M, Fugo K, et al. Involvement of an NKG2D ligand H60c in epidermal dendritic T cell-mediated wound repair. J Immunol. 2012;188:3972-9 pubmed publisher
Nice T, Coscoy L, Raulet D. Posttranslational regulation of the NKG2D ligand Mult1 in response to cell stress. J Exp Med. 2009;206:287-98 pubmed publisher
Dressel R, Schindehütte J, Kuhlmann T, Elsner L, Novota P, Baier P, et al. The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response. PLoS ONE. 2008;3:e2622 pubmed publisher
product information
master code :
MAB2588
SKU :
MAB2588
product name :
Mouse ULBP-1/MULT-1 Antibody
unit size :
100 ug (also 25 ug)
description :
The Mouse ULBP-1/MULT-1 Antibody from R&D Systems is a rat monoclonal antibody to ULBP-1. This antibody reacts with mouse. The Mouse ULBP-1/MULT-1 Antibody has been validated for the following applications: Flow Cytometry,ELISA Development,Western Blot,Functional Assay,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready.
target :
ULBP-1
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
237104
concentration :
LYOPH
conjugate :
Unconjugated
host :
Rat
immunogen :
BaF3 mouse pro-B cell line transfected with mouse ULBP-1/MULT-1
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Mouse
specificity :
Detects mouse ULBP-1/MULT-1.
gene symbol :
ULBP1
applications :
Flow Cytometry,ELISA Development,Western Blot,Functional Assay,Immunohistochemistry-Frozen,Immunocytochemistry,CyTOF-ready
USD :
439 USD
alt names :
ALCAN-beta, MULT-1, N2DL1, N2DL-1, NKG2D ligand 1, NKG2DL, NKG2DL1, RAET1I, RAET1Ialcan-beta, Retinoic acid early transcript 1I, UL16 binding protein 1, UL16-binding protein 1, ULBP1
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.