product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human NG2/MCSP Antibody
catalog :
MAB2585
quantity :
100 ug (also 25 ug)
price :
459 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
LHM-2
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, mass cytometry
more info or order :
citations: 16
Published Application/Species/Sample/DilutionReference
  • mass cytometry; human; loading ...; fig 4a
van der Heide V, Jangra S, Cohen P, Rathnasinghe R, Aslam S, Aydillo T, et al. Limited extent and consequences of pancreatic SARS-CoV-2 infection. Cell Rep. 2022;38:110508 pubmed publisher
Valente S, Villacampa Lahoz M, Vasuri F, Pasquinelli G. Immunohistochemical and Ultrastructural Characterization of Telocytes in Normal and Diabetic Human Kidneys. Biomolecules. 2024;14: pubmed publisher
Larabee J, Doyle D, Ahmed U, Shadid T, Sharp R, Jones K, et al. Discovery of Hippo signaling as a regulator of CSPG4 expression and as a therapeutic target for Clostridioides difficile disease. PLoS Pathog. 2023;19:e1011272 pubmed publisher
Wang J, Wuethrich A, Sina A, Lane R, Lin L, Wang Y, et al. Tracking extracellular vesicle phenotypic changes enables treatment monitoring in melanoma. Sci Adv. 2020;6:eaax3223 pubmed publisher
Kumamoto J, Nakanishi S, Makita M, Uesaka M, Yasugahira Y, Kobayashi Y, et al. Mathematical-model-guided development of full-thickness epidermal equivalent. Sci Rep. 2018;8:17999 pubmed publisher
Schultz N, Brannstrom K, Byman E, Moussaud S, Nielsen H, Olofsson A, et al. Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro. Aging Cell. 2018;17:e12728 pubmed publisher
Esteves C, Sheldrake T, Mesquita S, Pesántez J, Menghini T, Dawson L, et al. Isolation and characterization of equine native MSC populations. Stem Cell Res Ther. 2017;8:80 pubmed publisher
Esteves C, Sheldrake T, Dawson L, Menghini T, Rink B, Amilon K, et al. Equine Mesenchymal Stromal Cells Retain a Pericyte-Like Phenotype. Stem Cells Dev. 2017;26:964-972 pubmed publisher
Tsao S, Vaidyanathan R, Dey S, Carrascosa L, Christophi C, Cebon J, et al. Capture and On-chip analysis of Melanoma Cells Using Tunable Surface Shear forces. Sci Rep. 2016;6:19709 pubmed publisher
Higgins S, Fillmore H, Ashkan K, Butt A, Pilkington G. Dual targeting NG2 and GD3A using Mab-Zap immunotoxin results in reduced glioma cell viability in vitro. Anticancer Res. 2015;35:77-84 pubmed
Higgins S, Bolteus A, Donovan L, Hasegawa H, Doey L, Al Sarraj S, et al. Expression of the chondroitin sulphate proteoglycan, NG2, in paediatric brain tumors. Anticancer Res. 2014;34:6919-24 pubmed
Davaine J, Quillard T, Brion R, Lapérine O, Guyomarch B, Merlini T, et al. Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE. 2014;9:e107642 pubmed publisher
Keleg S, Titov A, Heller A, Giese T, Tjaden C, Ahmad S, et al. Chondroitin sulfate proteoglycan CSPG4 as a novel hypoxia-sensitive marker in pancreatic tumors. PLoS ONE. 2014;9:e100178 pubmed publisher
Corcoran R, ROTHENBERG S, Hata A, Faber A, Piris A, Nazarian R, et al. TORC1 suppression predicts responsiveness to RAF and MEK inhibition in BRAF-mutant melanoma. Sci Transl Med. 2013;5:196ra98 pubmed publisher
Benner E, Luciano D, Jo R, Abdi K, Paez Gonzalez P, Sheng H, et al. Protective astrogenesis from the SVZ niche after injury is controlled by Notch modulator Thbs4. Nature. 2013;497:369-73 pubmed publisher
Yao X, Qian C, Zhang Z, Tan M, Kort E, Yang X, et al. Two distinct types of blood vessels in clear cell renal cell carcinoma have contrasting prognostic implications. Clin Cancer Res. 2007;13:161-9 pubmed
product information
brand :
R&D Systems
master code :
MAB2585
SKU :
MAB2585
product name :
Human NG2/MCSP Antibody
unit size :
100 ug (also 25 ug)
seo description :
The Human NG2/MCSP Antibody from R&D Systems is a mouse monoclonal antibody to NG2/MCSP. This antibody reacts with equine,human,mouse. The Human NG2/MCSP Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry,CyTOF-ready.
target :
NG2/MCSP
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. See Certificate of Analysis for details. *Small pack size (-SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
LHM-2
concentration :
LYOPH
conjugate :
Unconjugated
dilution :
Western Blot 1 ug/mL, Flow Cytometry 0.25 ug/10^6 cells, Immunohistochemistry 8-25 ug/mL, CyTOF-ready
host :
Mouse
immunogen :
Human melanoma cells
isotype :
IgG1
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Equine,Human,Mouse
specificity :
Detects human NG2/MCSP in Western blots.
gene symbol :
CSPG4
top caption :
Detection of Human NG2/MCSP antibody by Western Blot.
applications :
CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunocytochemistry
USD :
459 USD
alt names :
AN2, chondroitin sulfate proteoglycan 4, chondroitin sulfate proteoglycan 4 (melanoma-associated), CSPG4, EC 3.6.3, HMW-MAA, MCSP, MCSPChondroitin sulfate proteoglycan NG2, MCSPG, MCSPGMelanoma chondroitin sulfate proteoglycan, MEL-CSPG, MSK16Melanoma-associated chondroitin sulfate proteoglycan, NG2EC 2.7.8
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.