Human beta-NGF Antibody | R&D Systems MAB256 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human beta-NGF Antibody

catalog :

MAB256

quantity :

100 ug (also 25 ug, 500 ug)

price :

359 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

25623

reactivity :

human

application :

neutralization

citations: 7

Published Application/Species/Sample/Dilution	Reference
ELISA; human; loading ...; fig 2	Oddone F, Roberti G, Micera A, Busanello A, Bonini S, Quaranta L, et al. Exploring Serum Levels of Brain Derived Neurotrophic Factor and Nerve Growth Factor Across Glaucoma Stages. PLoS ONE. 2017;12:e0168565 pubmed publisher
	Kolli S, Bojic S, Ghareeb A, Kurzawa Akanbi M, Figueiredo F, Lako M. The Role of Nerve Growth Factor in Maintaining Proliferative Capacity, Colony-Forming Efficiency, and the Limbal Stem Cell Phenotype. Stem Cells. 2019;37:139-149 pubmed publisher
	Kisiswa L, Fernández Suárez D, Sergaki M, Ibanez C. RIP2 Gates TRAF6 Interaction with Death Receptor p75NTR to Regulate Cerebellar Granule Neuron Survival. Cell Rep. 2018;24:1013-1024 pubmed publisher
	Malerba F, Paoletti F, Bruni Ercole B, Materazzi S, Nassini R, Coppi E, et al. Functional Characterization of Human ProNGF and NGF Mutants: Identification of NGF P61SR100E as a "Painless" Lead Investigational Candidate for Therapeutic Applications. PLoS ONE. 2015;10:e0136425 pubmed publisher
	Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed publisher
	Quarcoo D, Schulte Herbrüggen O, Lommatzsch M, Schierhorn K, Hoyle G, Renz H, et al. Nerve growth factor induces increased airway inflammation via a neuropeptide-dependent mechanism in a transgenic animal model of allergic airway inflammation. Clin Exp Allergy. 2004;34:1146-51 pubmed
	Dollé L, El Yazidi Belkoura I, Adriaenssens E, Nurcombe V, Hondermarck H. Nerve growth factor overexpression and autocrine loop in breast cancer cells. Oncogene. 2003;22:5592-601 pubmed

product information

brand :

R&D Systems

master code :

MAB256

SKU :

MAB256-100

product name :

Human beta-NGF Antibody

description :

The Human beta-NGF Antibody from R&D Systems is a mouse monoclonal antibody to beta-NGF. This antibody reacts with human. The Human beta-NGF Antibody has been validated for the following applications: Neutralization, ELISA Capture (Matched Antibody Pair).

target :

beta-NGF

category :

Primary Antibodies

unit size :

100 ug (also 25 ug, 500 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

25623

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human beta-NGF, Ser122-Ala241, Accession # CAA36832

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human beta-NGF in ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant mouse (rm) beta-NGF and recombinant rat (rr) beta-NGF is observed and less than 5% cross-reactivity with recombinant human (rh) BDNF, rhNT-3, and rhNT-4 is observed. This antibody neutralizes the bioactivity of rh beta-NGF, rm beta-NGF, and rr beta-NGF.

gene symbol :

NGF

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

catalog number base :

MAB256

accessionNumbers :

CAA36832

applications :

Neutralization, ELISA Capture (Matched Antibody Pair)

2020 USD :

339

2021 USD :

359 USD

alt names :

Beta nerve growth factor precursor, beta-nerve growth factor, betaNGF, Beta-NGF, HSAN5, MGC161426, nerve growth factor (beta polypeptide), nerve growth factor, beta subunit, NGFB, NGFBMGC161428

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.