CD155/PVR Antibody | R&D Systems MAB25301 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

CD155/PVR Antibody

catalog :

MAB25301

quantity :

100 ug (also 25 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

300907

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Joung J, Kirchgatterer P, Singh A, Cho J, Nety S, Larson R, et al. CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity. Nat Commun. 2022;13:1606 pubmed publisher
Reches A, Ophir Y, Stein N, Kol I, Isaacson B, Charpak Amikam Y, et al. Nectin4 is a novel TIGIT ligand which combines checkpoint inhibition and tumor specificity. J Immunother Cancer. 2020;8: pubmed publisher
Cuce M, Gallo Cantafio M, Siciliano M, Riillo C, Caracciolo D, Scionti F, et al. Trabectedin triggers direct and NK-mediated cytotoxicity in multiple myeloma. J Hematol Oncol. 2019;12:32 pubmed publisher
Costa D, Vené R, Benelli R, Romairone E, Scabini S, Catellani S, et al. Targeting the Epidermal Growth Factor Receptor Can Counteract the Inhibition of Natural Killer Cell Function Exerted by Colorectal Tumor-Associated Fibroblasts. Front Immunol. 2018;9:1150 pubmed publisher
Gur C, Ibrahim Y, Isaacson B, Yamin R, Abed J, Gamliel M, et al. Binding of the Fap2 protein of Fusobacterium nucleatum to human inhibitory receptor TIGIT protects tumors from immune cell attack. Immunity. 2015;42:344-355 pubmed publisher
Stanietsky N, Rovis T, Glasner A, Seidel E, Tsukerman P, Yamin R, et al. Mouse TIGIT inhibits NK-cell cytotoxicity upon interaction with PVR. Eur J Immunol. 2013;43:2138-50 pubmed publisher
MADRID A, Ganem D. Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44. J Virol. 2012;86:8693-704 pubmed publisher
Dupuy S, Lambert M, Zucman D, Choukem S, Tognarelli S, Pagès C, et al. Human Herpesvirus 8 (HHV8) sequentially shapes the NK cell repertoire during the course of asymptomatic infection and Kaposi sarcoma. PLoS Pathog. 2012;8:e1002486 pubmed publisher
Perier A, Fregni G, Wittnebel S, Gad S, Allard M, Gervois N, et al. Mutations of the von Hippel-Lindau gene confer increased susceptibility to natural killer cells of clear-cell renal cell carcinoma. Oncogene. 2011;30:2622-32 pubmed publisher

image

image 1 :

Detection of CD155/PVR antibody in U937 Human Cell Line antibody by Flow Cytometry.

product information

brand :

R&D Systems, a Bio-Techne brand

catalog number base :

MAB25301

SKU :

MAB25301

product name :

CD155/PVR Antibody

description :

The Human CD155/PVR Antibody from R&D Systems is a mouse monoclonal antibody to CD155/PVR. This antibody reacts with human. The Human CD155/PVR Antibody has been validated for the following applications: Immunocytochemistry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot.

target :

CD155/PVR

unit size :

100 ug (also 25 ug)

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

300907

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

Mouse myeloma cell line NS0-derived recombinant human CD155/PVR, Gly27-Asn343, Accession # AAH15542

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human CD155/PVR in direct ELISAs and Western blots.

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

gene symbol :

PVR

accessionNumbers :

AAH15542

applications :

Immunocytochemistry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot

product keywords :

MAB25301, hCD155 Mab Cl 300907, Mouse Anti-Human CD155/PVR Monoclonal Antibody, Anti-CD155, Anti-PVR, Mouse Anti Human CD155/PVR Monoclonal Antibody, Anti-hCD155, MAB253O1, immunechecktargets, Nectin-like family, nectin, necl, necl-5, Poliovirus Receptor, nectinandnectin-likereceptorsligands

USD :

469

USD 2025 :

489 USD

alt names :

CD155, CD155 antigen, HVED, Necl-5, NECL5, nectin-like 5, Nectin-like protein 5, poliovirus receptor, PVR, PVS, PVSFLJ25946, Tage4

more info or order :

R&D Systems product webpage