Integrin alpha V beta 5 Antibody | R&D Systems MAB2528 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Integrin alpha V beta 5 Antibody

catalog :

MAB2528

quantity :

100 ug (also 25 ug)

price :

449 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

P5H9

reactivity :

human

application :

immunocytochemistry, immunoprecipitation, flow cytometry

more info or order :

R&D Systems product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s2	Jung K, Son M, Lee S, Kim J, Ko D, Yoo S, et al. Antibody-mediated delivery of a viral MHC-I epitope into the cytosol of target tumor cells repurposes virus-specific CD8+ T cells for cancer immunotherapy. Mol Cancer. 2022;21:102 pubmed publisher
	Gringhuis S, Kaptein T, Remmerswaal E, Drewniak A, Wevers B, Theelen B, et al. Fungal sensing by dectin-1 directs the non-pathogenic polarization of TH17 cells through balanced type I IFN responses in human DCs. Nat Immunol. 2022;23:1735-1748 pubmed publisher
	Shin S, Kim J, Park S, Jun S, Kweon H, Choi D, et al. Direct targeting of oncogenic RAS mutants with a tumor-specific cytosol-penetrating antibody inhibits RAS mutant-driven tumor growth. Sci Adv. 2020;6:eaay2174 pubmed publisher
	Garcia Moure M, Martinez Vélez N, Gonzalez Huarriz M, Marrodán L, Cascallo M, Alemany R, et al. The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models. Sci Rep. 2019;9:14368 pubmed publisher
	Peterman E, Gibieža P, Schafer J, Skeberdis V, Kaupinis A, Valius M, et al. The post-abscission midbody is an intracellular signaling organelle that regulates cell proliferation. Nat Commun. 2019;10:3181 pubmed publisher
	Huang H, Dong Y, Zhang Y, Ru D, Wu Z, Zhang J, et al. GSH-sensitive Pt(IV) prodrug-loaded phase-transitional nanoparticles with a hybrid lipid-polymer shell for precise theranostics against ovarian cancer. Theranostics. 2019;9:1047-1065 pubmed publisher
	Wei J, Marisetty A, Schrand B, Gabrusiewicz K, Hashimoto Y, Ott M, et al. Osteopontin mediates glioblastoma-associated macrophage infiltration and is a potential therapeutic target. J Clin Invest. 2019;129:137-149 pubmed publisher
	Gillespie S, Tedesco L, Wang L, Bernstein A. The deubiquitylase USP10 regulates integrin β1 and β5 and fibrotic wound healing. J Cell Sci. 2017;130:3481-3495 pubmed publisher
	Miyano K, Cabral H, Miura Y, Matsumoto Y, Mochida Y, Kinoh H, et al. cRGD peptide installation on cisplatin-loaded nanomedicines enhances efficacy against locally advanced head and neck squamous cell carcinoma bearing cancer stem-like cells. J Control Release. 2017;261:275-286 pubmed publisher
	Burgett M, Lathia J, Roth P, Nowacki A, Galileo D, Pugacheva E, et al. Direct contact with perivascular tumor cells enhances integrin ?v?3 signaling and migration of endothelial cells. Oncotarget. 2016;7:43852-43867 pubmed publisher
	Shen Y, Yang F, Wang H, Cai Z, Xu Y, Zhao A, et al. Arg-Gly-Asp (RGD)-Modified E1A/E1B Double Mutant Adenovirus Enhances Antitumor Activity in Prostate Cancer Cells In Vitro and in Mice. PLoS ONE. 2016;11:e0147173 pubmed publisher
	Dixon K, O Flynn J, van der Kooij S, van Kooten C. Phagocytosis of apoptotic or necrotic cells differentially regulates the transcriptional expression of IL-12 family members in dendritic cells. J Leukoc Biol. 2014;96:313-24 pubmed publisher
	Mathieu M, Iampietro M, Chuchana P, Guérit D, Djouad F, Noel D, et al. Involvement of angiopoietin-like 4 in matrix remodeling during chondrogenic differentiation of mesenchymal stem cells. J Biol Chem. 2014;289:8402-12 pubmed publisher
	Wang L, Pedroja B, Meyers E, Garcia A, Twining S, Bernstein A. Degradation of internalized ?v?5 integrin is controlled by uPAR bound uPA: effect on ?1 integrin activity and ?-SMA stress fiber assembly. PLoS ONE. 2012;7:e33915 pubmed publisher
	Cabezón R, Sintes J, Llinàs L, Benitez Ribas D. Analysis of HLDA9 mAbs on plasmacytoid dendritic cells. Immunol Lett. 2011;134:167-73 pubmed publisher

image

image 1 :

Integrin aVss5 antibody in HT1080 Human Cell Line by Immunocytochemistry (ICC).

product information

brand :

R&D Systems, a Bio-Techne Brand

catalog number base :

MAB2528

SKU :

MAB2528

product name :

Integrin alpha V beta 5 Antibody

Description :

The Human Integrin alpha V beta 5 Antibody from R&D Systems is a mouse monoclonal antibody to Integrin alpha V beta 5. This antibody reacts with human. The Human Integrin alpha V beta 5 Antibody has been validated for the following applications: Flow Cytometry, Immunoprecipitation, Adhesion Blockade, Immunocytochemistry, CyTOF-ready.

target :

Integrin alpha V beta 5

category :

Primary Antibodies

unit size :

100 ug (also 25 ug)

buffer :

Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

clonality :

Monoclonal

clone :

P5H9

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

HT1080 human fibrosarcoma cell line

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human Integrin alpha V beta 5. Recognizes the human Integrin alpha V beta 5 heterodimer and does not recognize the alpha V subunit in association with any other beta subunits.

gene symbol :

ITGAV

endotoxin note :

<0.10 EU per 1 µg of the antibody by the LAL method.

applications :

Flow Cytometry, Immunoprecipitation, Adhesion Blockade, Immunocytochemistry, CyTOF-ready

USD :

449 USD

alt names :

CD51, integrin subunit alpha V, ITGAV, ITGB5, MSK8, Vitronectin Receptor alpha, VNRA, VTNR

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage