Human LIF Antibody | R&D Systems MAB250-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human LIF Antibody

catalog :

MAB250-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9824

reactivity :

human

application :

western blot, immunohistochemistry, neutralization, immunohistochemistry - frozen section

more info or order :

R&D Systems product webpage

citations: 8

Reference
Kano F, Hashimoto N, Liu Y, Xia L, Nishihara T, Oki W, et al. Therapeutic benefits of factors derived from stem cells from human exfoliated deciduous teeth for radiation-induced mouse xerostomia. Sci Rep. 2023;13:2706 pubmed publisher
Ke N, Chen L, Liu Q, Xiong H, Chen X, Zhou X. Downregulation of miR-211-5p Promotes Carboplatin Resistance in Human Retinoblastoma Y79 Cells by Affecting the GDNF-LIF Interaction. Front Oncol. 2022;12:848733 pubmed publisher
Chen X, Hausman B, Luo G, Zhou G, Murakami S, Rubin J, et al. Protein kinase inhibitor ? reciprocally regulates osteoblast and adipocyte differentiation by downregulating leukemia inhibitory factor. Stem Cells. 2013;31:2789-99 pubmed publisher
Morrison C, Mancini S, Cipollone J, Kappelhoff R, Roskelley C, Overall C. Microarray and proteomic analysis of breast cancer cell and osteoblast co-cultures: role of osteoblast matrix metalloproteinase (MMP)-13 in bone metastasis. J Biol Chem. 2011;286:34271-85 pubmed publisher
Simamura E, Shimada H, Higashi N, Uchishiba M, Otani H, Hatta T. Maternal leukemia inhibitory factor (LIF) promotes fetal neurogenesis via a LIF-ACTH-LIF signaling relay pathway. Endocrinology. 2010;151:1853-62 pubmed publisher
Duluc D, Delneste Y, Tan F, Moles M, Grimaud L, Lenoir J, et al. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood. 2007;110:4319-30 pubmed
Abir R, Fisch B, Jin S, Barnnet M, Freimann S, van den Hurk R, et al. Immunocytochemical detection and RT-PCR expression of leukaemia inhibitory factor and its receptor in human fetal and adult ovaries. Mol Hum Reprod. 2004;10:313-9 pubmed
Hess S, Rheinheimer C, Tidow F, Bartling G, Kaps C, Lauber J, et al. The reprogrammed host: Chlamydia trachomatis-induced up-regulation of glycoprotein 130 cytokines, transcription factors, and antiapoptotic genes. Arthritis Rheum. 2001;44:2392-401 pubmed

product information

master code :

MAB250

SKU :

MAB250-100

product name :

Human LIF Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human LIF Antibody from R&D Systems is a mouse monoclonal antibody to LIF. This antibody reacts with human. The Human LIF Antibody has been validated for the following applications: ELISA Development,Western Blot,Neutralization,Immunohistochemistry-Frozen,Immunohistochemistry.

target :

LIF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

9824

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human LIF

isotype :

IgG2b

purity :

Protein A or G purified from ascites

species :

Human

specificity :

Detects human LIF in ELISAs and Western blots. In sandwich immunoassays, no significant cross-reactivity or interference with recombinant human (rh) IL-1 alpha , rhIL-1▀, rhIL-2, rhIL-3, rhIL-4, rhIL-6, rhIL-7, rhIL-8, rhG-CSF, rhGM-CSF, rhOSM, rhTGF┐▀1, rhTNF-alpha , rhTNF┐▀, recombinant mouse (rm) IL-1▀, rmIL-3, rmIL-4, rmIL-5, rmIL-6, rmIL-7, rmGM-CSF, bovine (b) FGF acidic, bFGF basic, human (h) PDGF, porcine (p) PDGF, hTGF┐▀1, pTGF┐▀1.2, or pTGF┐▀2 is observed.

gene symbol :

LIF

endotoxin note :

<0.10 EU per 1 ╡g of the antibody by the LAL method.

top caption :

Cell Proliferation Induced by LIF and Neutralization by Human LIF Antibody.

applications :

ELISA Development,Western Blot,Neutralization,Immunohistochemistry-Frozen,Immunohistochemistry

USD :

469 USD

alt names :

CDF, D factor, DIA, differentiation inhibitory activity, differentiation stimulating factor, Differentiation-stimulating factor, Emfilermin, HILDA, HILDAcholinergic differentiation factor, leukemia inhibitory factor, leukemia inhibitory factor (cholinergic differentiation factor), Melanoma-derived LPL inhibitor, MLPLI

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage