Human BDNF Antibody | R&D Systems MAB248-100 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human BDNF Antibody

catalog :

MAB248-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

35928

reactivity :

human, mouse, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, neutralization, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 12

Reference
Papp T, Ferenczi Z, Szilagyi B, Petro M, Varga A, K xf3 kai E, et al. Ultrasound Used for Diagnostic Imaging Facilitates Dendritic Branching of Developing Neurons in the Mouse Cortex. Front Neurosci. 2022;16:803356 pubmed publisher
Sun W, Cheng H, Yang Y, Tang D, Li X, An L. Requirements of Postnatal proBDNF in the Hippocampus for Spatial Memory Consolidation and Neural Function. Front Cell Dev Biol. 2021;9:678182 pubmed publisher
Baptista J, Traynelis V, Liberti E, Fontes R. Expression of degenerative markers in intervertebral discs of young and elderly asymptomatic individuals. PLoS ONE. 2020;15:e0228155 pubmed publisher
Rudyk C, Dwyer Z, Hayley S. Leucine-rich repeat kinase-2 (LRRK2) modulates paraquat-induced inflammatory sickness and stress phenotype. J Neuroinflammation. 2019;16:120 pubmed publisher
Todoroki K, Ogasawara S, Akiba J, Nakayama M, Naito Y, Seki N, et al. CD44v3+/CD24- cells possess cancer stem cell-like properties in human oral squamous cell carcinoma. Int J Oncol. 2016;48:99-109 pubmed publisher
Vanhecke E, Adriaenssens E, Verbeke S, Meignan S, Germain E, Berteaux N, et al. Brain-derived neurotrophic factor and neurotrophin-4/5 are expressed in breast cancer and can be targeted to inhibit tumor cell survival. Clin Cancer Res. 2011;17:1741-52 pubmed publisher
Diekmann H, Anichtchik O, Fleming A, Futter M, Goldsmith P, Roach A, et al. Decreased BDNF levels are a major contributor to the embryonic phenotype of huntingtin knockdown zebrafish. J Neurosci. 2009;29:1343-9 pubmed publisher
Sung S, Hsieh C, Law A, Zhau H, Pathak S, Multani A, et al. Coevolution of prostate cancer and bone stroma in three-dimensional coculture: implications for cancer growth and metastasis. Cancer Res. 2008;68:9996-10003 pubmed publisher
Tang S, Machaalani R, Waters K. Brain-derived neurotrophic factor (BDNF) and TrkB in the piglet brainstem after post-natal nicotine and intermittent hypercapnic hypoxia. Brain Res. 2008;1232:195-205 pubmed publisher
Berzi A, Ayata C, Cavalcante P, Falcone C, Candiago E, Motta T, et al. BDNF and its receptors in human myasthenic thymus: implications for cell fate in thymic pathology. J Neuroimmunol. 2008;197:128-39 pubmed publisher
Samah B, Porcheray F, Gras G. Neurotrophins modulate monocyte chemotaxis without affecting macrophage function. Clin Exp Immunol. 2008;151:476-86 pubmed publisher
Peiris T, Machaalani R, Waters K. Brain-derived neurotrophic factor mRNA and protein in the piglet brainstem and effects of Intermittent Hypercapnic Hypoxia. Brain Res. 2004;1029:11-23 pubmed

product information

brand :

R&D Systems

master code :

MAB248

SKU :

MAB248-100

product name :

Human BDNF Antibody

unit size :

100 ug (also 25 ug, 500 ug)

seo description :

The Human BDNF Antibody from R&D Systems is a mouse monoclonal antibody to BDNF. This antibody reacts with human,mouse,porcine,transgenic mouse,fish - danio rerio (zebrafish). The Human BDNF Antibody has been validated for the following applications: Western Blot,Neutralization,Immunohistochemistry,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Immunocytochemistry.

target :

BDNF

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

35928

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Immunohistochemistry 8-25 ug/mL

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human BDNF, Arg128-Arg247, Accession # P23560

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Porcine,Transgenic Mouse,Fish - Danio rerio (Zebrafish)

specificity :

Detects human BDNF in direct ELISAs and Western blots. In direct ELISAs and Western blots, this antibody shows approximately 5% cross-reactivity with recombinant human (rh) ▀-NGF and rr▀-NGF.

gene symbol :

BDNF

top caption :

BDNF antibody in Human Spinal Cord by Immunohistochemistry (IHC-P).

accessionNumbers :

P23560

applications :

Immunohistochemistry,Western Blot,Immunohistochemistry-Paraffin,Immunohistochemistry-Frozen,Neutralization,Immunocytochemistry

USD :

479 USD

alt names :

abrineurin, ANON2, brain-derived neurotrophic factor, BULN2, MGC34632, neurotrophin

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.