This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
R&D Systems
product type :
antibody
product name :
Human IL-15 Antibody
catalog :
MAB2471
quantity :
100 ug (also 25 ug, 500 ug)
price :
369 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
34559
reactivity :
human
application :
western blot, neutralization, flow cytometry
citations: 12
Published Application/Species/Sample/DilutionReference
  • flow cytometry; human; loading ...; fig 3a
Gorvel L, Korenfeld D, Tung T, Klechevsky E. Dendritic Cell-Derived IL-32?: A Novel Inhibitory Cytokine of NK Cell Function. J Immunol. 2017;199:1290-1300 pubmed publisher
  • flow cytometry; human; loading ...; fig 2a
Pangrazzi L, Meryk A, Naismith E, Koziel R, Lair J, Krismer M, et al. "Inflamm-aging" influences immune cell survival factors in human bone marrow. Eur J Immunol. 2017;47:481-492 pubmed publisher
Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, et al. Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis. J Neuroinflammation. 2018;15:114 pubmed publisher
Du Y, Tu G, Yang G, Li G, Yang D, Lang L, et al. MiR-205/YAP1 in Activated Fibroblasts of Breast Tumor Promotes VEGF-independent Angiogenesis through STAT3 Signaling. Theranostics. 2017;7:3972-3988 pubmed publisher
Van den Bergh J, Smits E, Versteven M, De Reu H, Berneman Z, Van Tendeloo V, et al. Characterization of Interleukin-15-Transpresenting Dendritic Cells for Clinical Use. J Immunol Res. 2017;2017:1975902 pubmed publisher
Ciccocioppo R, Gallia A, Avanzini M, Betti E, Picone C, Vanoli A, et al. A Refractory Celiac Patient Successfully Treated With Mesenchymal Stem Cell Infusions. Mayo Clin Proc. 2016;91:812-9 pubmed publisher
Anguille S, Van Acker H, Van den Bergh J, Willemen Y, Goossens H, Van Tendeloo V, et al. Interleukin-15 Dendritic Cells Harness NK Cell Cytotoxic Effector Function in a Contact- and IL-15-Dependent Manner. PLoS ONE. 2015;10:e0123340 pubmed publisher
Tsai C, Liong K, Gunalan M, Li N, Lim D, Fisher D, et al. Type I IFNs and IL-18 regulate the antiviral response of primary human γδ T cells against dendritic cells infected with Dengue virus. J Immunol. 2015;194:3890-900 pubmed publisher
Marra P, Mathew S, Grigoriadis A, Wu Y, Kyle Cezar F, Watkins J, et al. IL15RA drives antagonistic mechanisms of cancer development and immune control in lymphocyte-enriched triple-negative breast cancers. Cancer Res. 2014;74:4908-21 pubmed publisher
Muntasell A, Magri G, Pende D, Angulo A, Lopez Botet M. Inhibition of NKG2D expression in NK cells by cytokines secreted in response to human cytomegalovirus infection. Blood. 2010;115:5170-9 pubmed publisher
Tsukamoto K, Huang Y, Dorsey W, Carns B, Sharma V. Juxtacrine function of interleukin-15/interleukin-15 receptor system in tumour derived human B-cell lines. Clin Exp Immunol. 2006;146:559-66 pubmed
Ong P, Hamid Q, Travers J, Strickland I, Al Kerithy M, Boguniewicz M, et al. Decreased IL-15 may contribute to elevated IgE and acute inflammation in atopic dermatitis. J Immunol. 2002;168:505-10 pubmed
product information
brand :
R&D Systems
master code :
MAB2471
SKU :
MAB2471-100
product name :
Human IL-15 Antibody
description :
The Human IL-15 Antibody from R&D Systems is a mouse monoclonal antibody to IL-15. This antibody reacts with human. The Human IL-15 Antibody has been validated for the following applications: Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready.
target :
IL-15
category :
Primary Antibodies
unit size :
100 ug (also 25 ug, 500 ug)
buffer :
Lyophilized from a 0.2 µm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
clonality :
Monoclonal
clone :
34559
conjugate :
Unconjugated
host :
Mouse
immunogen :
E. coli -derived recombinant human IL-15, Asn49-Ser162, Accession # P40933
isotype :
IgG1
purity :
Protein A or G purified from ascites
species :
Human
specificity :
Detects human IL-15 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) IL-2, recombinant mouse IL-15, or rhIL-21 is observed.
gene symbol :
IL15
details of functionality :
ActivityAssaywCitation not found None None None
endotoxin note :
<0.10 EU per 1 µg of the antibody by the LAL method.
catalog number base :
MAB2471
accessionNumbers :
P40933
applications :
Western Blot, Neutralization, Intracellular Staining by Flow Cytometry, CyTOF-ready
2020 USD :
339
2021 USD :
369 USD
alt names :
IL15, IL-15MGC9721, interleukin 15, interleukin-15
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.