Human/Mouse Pax3/Pax7 Antibody | R&D Systems MAB2457 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human/Mouse Pax3/Pax7 Antibody

catalog :

MAB2457

quantity :

100 ug (also 25 ug)

price :

479 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

274212

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 19

Reference
Chauhan S, Lian E, Habib I, Liu Q, Anders N, Bugg M, et al. Entinostat as a combinatorial therapeutic for rhabdomyosarcoma. Sci Rep. 2024;14:18936 pubmed publisher
Azzag K, Bosnakovski D, Tungtur S, Salama P, Kyba M, Perlingeiro R. Transplantation of PSC-derived myogenic progenitors counteracts disease phenotypes in FSHD mice. NPJ Regen Med. 2022;7:43 pubmed publisher
Ramirez M, Badayeva Y, Yeung J, Wu J, Abdalla Wyse A, Yang E, et al. Temporal analysis of enhancers during mouse cerebellar development reveals dynamic and novel regulatory functions. elife. 2022;11: pubmed publisher
Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed publisher
Crawford K, Berlow N, Tsay J, Lazich M, Mancini M, Noakes C, et al. Case report for an adolescent with germline RET mutation and alveolar rhabdomyosarcoma. Cold Spring Harb Mol Case Stud. 2020;6: pubmed publisher
Stone O, Stainier D. Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. Dev Cell. 2019;: pubmed publisher
Bharathy N, Berlow N, Wang E, Abraham J, Settelmeyer T, Hooper J, et al. The HDAC3-SMARCA4-miR-27a axis promotes expression of the PAX3:FOXO1 fusion oncogene in rhabdomyosarcoma. Sci Signal. 2018;11: pubmed publisher
McBride M, Pulice J, Beird H, Ingram D, D Avino A, Shern J, et al. The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma. Cancer Cell. 2018;33:1128-1141.e7 pubmed publisher
Sahakyan V, Pozzo E, Duelen R, Deprest J, Sampaolesi M. Methotrexate and Valproic Acid Affect Early Neurogenesis of Human Amniotic Fluid Stem Cells from Myelomeningocele. Stem Cells Int. 2017;2017:6101609 pubmed publisher
Quattrocelli M, Swinnen M, Giacomazzi G, Camps J, BarthÃ©lemy I, Ceccarelli G, et al. Mesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscle. J Clin Invest. 2015;125:4463-82 pubmed publisher
Arts N, CanÃ© S, Hennequart M, Lamy J, Bommer G, Van den Eynde B, et al. microRNA-155, induced by interleukin-1ÃŸ, represses the expression of microphthalmia-associated transcription factor (MITF-M) in melanoma cells. PLoS ONE. 2015;10:e0122517 pubmed publisher
Shelton M, Metz J, Liu J, Carpenedo R, Demers S, Stanford W, et al. Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells. Stem Cell Reports. 2014;3:516-29 pubmed publisher
Abraham J, Núñez Álvarez Y, Hettmer S, Carrió E, Chen H, Nishijo K, et al. Lineage of origin in rhabdomyosarcoma informs pharmacological response. Genes Dev. 2014;28:1578-91 pubmed publisher
Kikuchi K, Hettmer S, Aslam M, Michalek J, Laub W, Wilky B, et al. Cell-cycle dependent expression of a translocation-mediated fusion oncogene mediates checkpoint adaptation in rhabdomyosarcoma. PLoS Genet. 2014;10:e1004107 pubmed publisher
Plouhinec J, Roche D, Pegoraro C, Figueiredo A, Maczkowiak F, Brunet L, et al. Pax3 and Zic1 trigger the early neural crest gene regulatory network by the direct activation of multiple key neural crest specifiers. Dev Biol. 2014;386:461-72 pubmed publisher
Awaya T, Kato T, Mizuno Y, Chang H, Niwa A, Umeda K, et al. Selective development of myogenic mesenchymal cells from human embryonic and induced pluripotent stem cells. PLoS ONE. 2012;7:e51638 pubmed publisher
Magli A, Schnettler E, Rinaldi F, Bremer P, Perlingeiro R. Functional dissection of Pax3 in paraxial mesoderm development and myogenesis. Stem Cells. 2013;31:59-70 pubmed publisher
Gianakopoulos P, Mehta V, Voronova A, Cao Y, Yao Z, Coutu J, et al. MyoD directly up-regulates premyogenic mesoderm factors during induction of skeletal myogenesis in stem cells. J Biol Chem. 2011;286:2517-25 pubmed publisher
Gang E, Bosnakovski D, Simsek T, To K, Perlingeiro R. Pax3 activation promotes the differentiation of mesenchymal stem cells toward the myogenic lineage. Exp Cell Res. 2008;314:1721-33 pubmed publisher

product information

brand :

R&D Systems

master code :

MAB2457

SKU :

MAB2457

product name :

Human/Mouse Pax3/Pax7 Antibody

unit size :

100 ug (also 25 ug)

seo description :

The Human/Mouse Pax3/Pax7 Antibody from R&D Systems is a mouse monoclonal antibody to Pax3/Pax7. This antibody reacts with human,mouse. The Human/Mouse Pax3/Pax7 Antibody has been validated for the following applications: Western Blot,Flow Cytometry,Functional Assay,Immunohistochemistry,Immunocytochemistry,Intracellular Staining by Flow Cytometry,CyTOF-ready.

target :

Pax3/Pax7

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

274212

concentration :

LYOPH

conjugate :

Unconjugated

dilution :

Western Blot 1 ug/mL, Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells, Immunocytochemistry 8-25 ug/mL, CyTOF-ready

host :

Mouse

immunogen :

E. coli -derived recombinant human Pax3 (isoform Pax3a), Met1-Ser215, Accession # NP_000429

isotype :

IgG2a

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse

specificity :

Detects human and mouse Pax3 and Pax7 in direct ELISAs and Western blots. In direct ELISAs, approximately 20% cross-reactivity with recombinant human (rh) Pax1 is observed, approximately 10% with rhPax6, and less than 2% with rhPax2, rhPax4, rhPax5, and rhPax9.

gene symbol :

PAX3

top caption :

Pax3 antibody in B16-F1 Mouse Cell Line by Immunocytochemistry (ICC).

accessionNumbers :

NP_000429

applications :

Intracellular Staining by Flow Cytometry,CyTOF-ready,Flow Cytometry,Immunohistochemistry,Western Blot,Immunocytochemistry,Functional Assay

USD :

479 USD

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage