product summary
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company name :
R&D Systems
product type :
antibody
product name :
Human ROBO4 Antibody
catalog :
MAB2454
quantity :
100 ug (also 25 ug)
price :
429 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
265703
reactivity :
human, mouse
application :
western blot, immunoprecipitation, flow cytometry
more info or order :
citations: 3
Reference
Xiao W, Pinilla Baquero A, Faulkner J, Song X, Prabhakar P, Qiu H, et al. Robo4 is constitutively shed by ADAMs from endothelial cells and the shed Robo4 functions to inhibit Slit3-induced angiogenesis. Sci Rep. 2022;12:4352 pubmed publisher
Rama N, Dubrac A, Mathivet T, Ní Chárthaigh R, Genet G, Cristofaro B, et al. Slit2 signaling through Robo1 and Robo2 is required for retinal neovascularization. Nat Med. 2015;21:483-91 pubmed publisher
Guijarro Muñoz I, Cuesta A, Alvarez Cienfuegos A, Geng J, Alvarez Vallina L, Sanz L. The axonal repellent Slit2 inhibits pericyte migration: potential implications in angiogenesis. Exp Cell Res. 2012;318:371-8 pubmed publisher
product information
master code :
MAB2454
SKU :
MAB2454
product name :
Human ROBO4 Antibody
unit size :
100 ug (also 25 ug)
description :
The Human ROBO4 Antibody from R&D Systems is a mouse monoclonal antibody to ROBO4. This antibody reacts with human,mouse. The Human ROBO4 Antibody has been validated for the following applications: Flow Cytometry,Immunoprecipitation,Western Blot,CyTOF-ready.
target :
ROBO4
category :
Primary Antibodies
buffer :
Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.
clonality :
Monoclonal
clone :
265703
concentration :
LYOPH
conjugate :
Unconjugated
host :
Mouse
immunogen :
Mouse myeloma cell line NS0-derived recombinant human ROBO4, Gln28-Arg467, Accession # Q8WZ75
isotype :
IgG2a
purity :
Protein A or G purified from hybridoma culture supernatant
species :
Human,Mouse
specificity :
Detects human ROBO4 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant rat ROBO1, recombinant human (rh) ROBO2, or rhROBO3 is observed.
gene symbol :
ROBO4
accessionNumbers :
Q8WZ75
applications :
Immunoprecipitation,Western Blot,Flow Cytometry,CyTOF-ready
USD :
429 USD
alt names :
ECSM4, FLJ20798, Magic roundabout, MGC133352, MGC133353, MRB, roundabout homolog 4, roundabout homolog 4, magic roundabout (Drosophila)
storage :
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.
more info or order :
company information
R&D Systems
614 McKinley Place N.E.
Minneapolis, MN 55413
info@RnDSystems.com
https://www.rndsystems.com
800 343-7475
headquarters: USA
R&D Systems develops and manufactures high-quality proteins and serves as a world leader in immunoassays. R&D Systems also produces quality antibodies, antibody arrays, stem cell and cell culture products, and cell selection and detection products, serving the life science and diagnostics industry.