Human IFN-alpha/▀ R1 Antibody | R&D Systems MAB245-100 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human IFN-alpha/▀ R1 Antibody

catalog :

MAB245-100

quantity :

100 ug (also 25 ug, 500 ug)

price :

489 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

85228

reactivity :

human

application :

western blot, neutralization, flow cytometry

more info or order :

R&D Systems product webpage

citations: 6

Reference
Chandler F, Reddy P, Bhutda S, Ross R, Datta A, Walden M, et al. Molecular glues that inhibit deubiquitylase activity and inflammatory signalling. bioRxiv. 2024;: pubmed publisher
Zhao L, He S, Liu Y, Zhao P, Bian Z, Qi Z. Inhibition of STAT Pathway Impairs Anti-Hepatitis C Virus Effect of Interferon Alpha. Cell Physiol Biochem. 2016;40:77-90 pubmed
He S, Wang W, Ren H, Zhao L, Qi Z. Interferon alpha and ribavirin collaboratively regulate p38 mitogen-activated protein kinase signaling in hepatoma cells. Cytokine. 2013;61:801-7 pubmed publisher
MADRID A, Ganem D. Kaposi's sarcoma-associated herpesvirus ORF54/dUTPase downregulates a ligand for the NK activating receptor NKp44. J Virol. 2012;86:8693-704 pubmed publisher
Konishi H, Okamoto K, Ohmori Y, Yoshino H, Ohmori H, Ashihara M, et al. An orally available, small-molecule interferon inhibits viral replication. Sci Rep. 2012;2:259 pubmed publisher
Zhou J, Huang J, Poon V, Chen D, Chan C, Ng F, et al. Functional dissection of an IFN-alpha/beta receptor 1 promoter variant that confers higher risk to chronic hepatitis B virus infection. J Hepatol. 2009;51:322-32 pubmed publisher

product information

master code :

MAB245

SKU :

MAB245-100

product name :

Human IFN-alpha/▀ R1 Antibody

unit size :

100 ug (also 25 ug, 500 ug)

description :

The Human IFN-alpha/ß R1 Antibody from R&D Systems is a mouse monoclonal antibody to IFN-alpha/beta R1. This antibody reacts with human. The Human IFN-alpha/ß R1 Antibody has been validated for the following applications: Flow Cytometry,Neutralization,Functional Assay,Western Blot,CyTOF-ready.

target :

IFN-alpha/beta R1

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

85228

conjugate :

Unconjugated

host :

Mouse

immunogen :

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human IFN-alpha/▀ R1, Lys28-Lys436, Accession # AAA52730

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human

specificity :

Detects human IFN-alpha/▀ R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha/▀ R2, rhIL-10 R▀, rhIL-10 R alpha , or rhIL-20 R▀.

gene symbol :

IFNAR1

accessionNumbers :

AAA52730

applications :

Flow Cytometry,Neutralization,Functional Assay,Western Blot,CyTOF-ready

USD :

489 USD

alt names :

alpha-type antiviral protein, AVP, beta-type antiviral protein, CRF2-1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, human interferon-alpha receptor (HuIFN-alpha-Rec)10IFRC, IFN-alpha/beta receptor 1, IFN-alpha-REC, IFNAR, IFN-aR1, IFNAR1, IFNBR, IFNbR1, IFN-bR1, IFN-R-1, interferon (alpha, beta and omega) receptor 1, interferon alpha/beta receptor 1, interferon-alpha/beta receptor alpha chain, interferon-beta receptor 1, Type I interferon receptor 1

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage