Human NKX2.5 Antibody | R&D Systems MAB2444 product information

product summary

company name :

R&D Systems

product type :

antibody

product name :

Human NKX2.5 Antibody

catalog :

MAB2444

quantity :

100 ug (also 25 ug)

price :

469 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

259416

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunocytochemistry, flow cytometry

more info or order :

R&D Systems product webpage

citations: 9

Reference
Feng W, Schriever H, Jiang S, Bais A, Wu H, Kostka D, et al. Computational profiling of hiPSC-derived heart organoids reveals chamber defects associated with NKX2-5 deficiency. Commun Biol. 2022;5:399 pubmed publisher
Liu F, Long D, Huang W, Peng W, Lan H, Zhou Y, et al. The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC. Int J Stem Cells. 2022;15:247-257 pubmed publisher
Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed publisher
Colunga T, Hayworth M, Kreß S, Reynolds D, Chen L, Nazor K, et al. Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair. Cell Rep. 2019;26:2566-2579.e10 pubmed publisher
Ranjbarvaziri S, Park S, Nguyen N, Gilmore W, Zhao P, Ardehali R. Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts. Genesis. 2017;55: pubmed publisher
Song I, Oh A, Kim J, Choi Y, Jeon Y, Ryu J, et al. The involvement of protein kinase C-Îµ in isoflurane induced preconditioning of human embryonic stem cell--derived Nkx2.5(+) cardiac progenitor cells. BMC Anesthesiol. 2016;16:13 pubmed publisher
Gregoire S, Karra R, Passer D, Deutsch M, Krane M, Feistritzer R, et al. Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation. Circ Res. 2013;112:900-10 pubmed publisher
Stefanovic S, Abboud N, Désilets S, Nury D, Cowan C, Puceat M. Interplay of Oct4 with Sox2 and Sox17: a molecular switch from stem cell pluripotency to specifying a cardiac fate. J Cell Biol. 2009;186:665-73 pubmed publisher
Jumabay M, Matsumoto T, Yokoyama S, Kano K, Kusumi Y, Masuko T, et al. Dedifferentiated fat cells convert to cardiomyocyte phenotype and repair infarcted cardiac tissue in rats. J Mol Cell Cardiol. 2009;47:565-75 pubmed publisher

product information

master code :

MAB2444

SKU :

MAB2444

product name :

Human NKX2.5 Antibody

unit size :

100 ug (also 25 ug)

description :

The Human NKX2.5 Antibody from R&D Systems is a mouse monoclonal antibody to NKX2.5. This antibody reacts with human,mouse,rat. The Human NKX2.5 Antibody has been validated for the following applications: Flow Cytometry,Immunohistochemistry,Immunocytochemistry.

target :

NKX2.5

category :

Primary Antibodies

buffer :

Lyophilized from a 0.2 ╡m filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 ╡m filtered solution in PBS.

clonality :

Monoclonal

clone :

259416

concentration :

LYOPH

conjugate :

Unconjugated

host :

Mouse

immunogen :

E. coli -derived recombinant human NKX2.5, Gln24-Arg137, Accession # P52952

isotype :

IgG1

purity :

Protein A or G purified from hybridoma culture supernatant

species :

Human,Mouse,Rat

specificity :

Detects human NKX-2.5 in direct ELISAs.

gene symbol :

NKX2-5

top caption :

NKX2 by Immunohistochemistry (IHC-P).5 antibody in Human Heart by Immunohistochemistry (IHC-P).

accessionNumbers :

P52952

applications :

Flow Cytometry,Immunohistochemistry,Immunocytochemistry

USD :

469 USD

alt names :

cardiac-specific homeo box, Cardiac-specific homeobox, cardiac-specific homeobox 1, CHNG5, CSX1, CSXFLJ97195, FLJ52202, FLJ99536, Homeobox protein CSX, Homeobox protein NK-2 homolog E, homeobox protein Nkx-2.5, NK2 transcription factor related, locus 5 (Drosophila), NKX2.5FLJ97166, NKX2-5, NKX2E, NKX2EFLJ97197, NKX4-1, tinman paralog

storage :

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 ░C as supplied. 1 month, 2 to 8 ░C under sterile conditions after reconstitution. 6 months, -20 to -70 ░C under sterile conditions after reconstitution.

more info or order :

R&D Systems product webpage